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MMST, MBBS
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MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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5FU-Gls 500 Injection


Product introduction

5FU-Gls 500 Injection is used in the treatment of cancers of stomach, colon, rectum, breast, and lungs. It may be used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

5FU-Gls 500 Injection is used to treat severe forms of a skin disease (psoriasis) and to treat several disorders of joint disorders leading to painful swelling and redness of the joints.

Uses of 5FU-Gls Injection

Benefits of 5FU-Gls Injection

In Cancer

5FU-Gls 500 Injection helps to treat certain kinds of cancer such as cancer of the breasts, lungs, colon, rectum etc. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. 5FU-Gls 500 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of 5FU-Gls Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of 5FU-Gls

  • Nausea
  • Vomiting
  • Hair loss
  • Diarrhea
  • Bronchospasm
  • Infection
  • Myelosuppression
  • Agranulocytosis (deficiency of granulocytes in the blood)
  • General discomfort
  • Itching
  • Skin exfoliation
  • Anemia (low number of red blood cells)
  • Febrile neutropenia
  • Angina (heart related chest pain)
  • ECG changes
  • Decreased immunity

How to use 5FU-Gls Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with 5FU-Gls 500 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
5FU-Gls 500 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
5FU-Gls 500 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
5FU-Gls 500 Injection may cause side effects which could affect your ability to drive.
5FU-Gls 500 Injection can cause side effects such as nausea and can also produce adverse events on your nervous system which cause visual changes.This may affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
5FU-Gls 500 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of 5FU-Gls 500 Injection may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
5FU-Gls 500 Injection should be used with caution in patients with liver disease. Dose adjustment of 5FU-Gls 500 Injection may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
5FU-Gls 500 Injection
₹27.0/Injection
Fluracil 500mg Injection
Biochem Pharmaceutical Industries
₹24.05/injection
11% cheaper
Florac 500mg Injection
Cadila Pharmaceuticals Ltd
₹21.26/injection
21% cheaper
Kucil 500mg Injection
Khandelwal Laboratories Pvt Ltd
₹20.96/injection
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₹23/injection
15% cheaper
Fivoflu 500mg Injection
Fresenius Kabi India Pvt Ltd
₹23.07/injection
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Quick tips

  • 5FU-Gls 500 Injection helps treat cancers of stomach, colon, rectum, breast, and lungs.
  • It is given as an injection into a vein, or as a drip (infusion) into a vein or artery.
  • The dose and the number of treatment cycles needed will depend on the type and stage of cancer that is being treated.
  • It may cause dizziness and visual changes. Do not drive or do anything requiring concentration until you know how it affects you.
  • Your doctor may regularly monitor your blood cells and liver function during treatment with this medicine.

Fact Box

Chemical Class
Pyrimidine Analog
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites

Patient concerns

arrow
GE junction adenocarcinoma treated preoperatively with 3 cycles of ECF regimen 1st cycle Day 1 Epirubicin 85mg Day1, 2 Cisplatin 50mg Day 1,2,3 5FU The total WBC count has fallen to 4300 from 9500 what measures are taken in the next cycle to prevent neutropenia or reduce bone marrow suppression ? will any of the drug doses be reduced for this?
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
At this count nothing has to be doneThis is a normal blood count
How we can find out parient is CA and which report we can do for know the patient is CA
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Thr is no single test for cancerWhich cancer ur looking for
arrow

FAQs

Is fluorouracil a vesicant?

No, fluorouracil is not a vesicant (irritant).

Is fluorouracil safe?

Fluorouracil is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Is fluorouracil a steroid?

No, flurouracil is not a steroid.

Is fluorouracil cream chemotherapy?

Fluorouracil is used as chemotherapy for the treatment of cancers.

Is fluorouracil cream for warts?

Yes, fluorouracil is used for the treatment of warts.

Is fluorouracil the same as efudex?

Efudex is a brand name (trade name) for fluorouracil.

Does fluorouracil affect normal skin?

Fluorouracil has minimal effect on the surrounding healthy skin.

Does fluorouracil cause hair loss?

Yes, fluorouracil may cause temporary hair loss.

Does fluorouracil cause scarring?

No, fluorouracil is not known to cause scarring.

Does fluorouracil cause headaches?

Though headache is not a common side effect of fluorouracil, it may occur uncommonly is some people.

Why does fluorouracil cause fatigue?

As with any chemotherapy for cancer, fluorouracil causes fatigue which is attributed to be of multi-factor origin, but inflammation and anemia are thought to be the most important factors.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 946-47.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 561-63.
  3. Fluorouracil. Hurley, Maidenhead: Hospira UK Ltd.; 1985 [revised Jan. 2017]. [Accessed 29 Jan. 2019] (online) Available from:External Link
  4. Drugs.com. Fluorouracil Pregnancy and Breastfeeding Warnings. [Accesses on 27 Mar. 2019] (online) Available from:External Link
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Fluorouracil. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Marketer details

Name: GLS Pharma Ltd.
Address: R-4, Khirki Main Road, Malviya Nagar New Delhi- 110 017, (India)
Country of origin: India

MRP
27
Inclusive of all taxes
10.0 ml in 1 ampoule
SOLD OUT
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