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Endoxan N 500mg Injection
Prescription Required
Product introduction
Endoxan N 500mg Injection is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children after other treatments have not worked. It may be also used to treat other conditions, as determined by the doctor.
Endoxan N 500mg Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Endoxan N 500mg Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Endoxan N Injection
Benefits of Endoxan N Injection
In Cancer
Endoxan N 500mg Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Endoxan N 500mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Nephrotic syndrome
Nephrotic syndrome is a kidney disorder that causes your body to pass too much protein in your urine accompanied with excessive swelling over various parts of the body such as around the eyes and in the feet and ankles. Endoxan N 500mg Injection works by suppressing the immune system thereby reducing inflammation and swelling that occur in nephrotic syndrome. It reduces the protein in the urine and also helps in getting rid of the extra fluid, thereby relieving the swelling over different parts of the body. This helps to restore the normal kidney function and prevents further damage to the kidneys.
Side effects of Endoxan N Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Endoxan N
- Vomiting
- Nausea
- Hair loss
- Fever
- Blood in urine
- Diarrhea
- Decreased white blood cell count (neutrophils)
How to use Endoxan N Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Endoxan N Injection works
Endoxan N 500mg Injection is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication. This is how it works against cancer.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Endoxan N 500mg Injection.
Pregnancy
CONSULT YOUR DOCTOR
Endoxan N 500mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Endoxan N 500mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Endoxan N 500mg Injection may cause side effects which could affect your ability to drive.
Endoxan N 500mg Injection may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
Endoxan N 500mg Injection may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
Kidney
CAUTION
Endoxan N 500mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Endoxan N 500mg Injection may be needed. Please consult your doctor.
Liver
CAUTION
Endoxan N 500mg Injection should be used with caution in patients with liver disease. Dose adjustment of Endoxan N 500mg Injection may be needed. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Endoxan N 500mg Injection
₹42/Injection
₹71.92/injection
14% cheaper
Cydoxan 500mg Injection
Alkem Laboratories Ltd
₹68.4/injection
19% cheaper
Cyclocel 500mg Injection
Celon Laboratories Ltd
₹75/injection
11% cheaper
Phosmid 500mg Injection
Neon Laboratories Ltd
₹44/injection
48% cheaper
Cycram 500mg Injection
Vhb Life Sciences Inc
₹59.52/injection
29% cheaper
Quick tips
- Endoxan N 500mg Injection helps in the treatment of cancer.
- It is injected into the vein by a doctor or healthcare professional.
- Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
- Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
- You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
- Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
- Do not take Endoxan N 500mg Injection if you are pregnant or breastfeeding.
- Use effective contraception method to prevent pregnancy while taking this medicine.
Fact Box
Chemical Class
Nitrogen Mustard Compounds
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkylating agent
Patient concerns
User feedback
Patients taking Endoxan N 500mg Injection
Once A Day
33%
Twice A Week
22%
Once A Week
22%
Once A Month
22%
What are you using Endoxan N Injection for?
Others
62%
Breast cancer
25%
Non-small cel*
12%
*Non-small cell lung cancer
How much was the improvement?
Poor
100%
FAQs
Can Endoxan N 500mg Injection cause infertility?
Yes, Endoxan N 500mg Injection can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Endoxan N 500mg Injection.
Do I need to avoid sun exposure during treatment with Endoxan N 500mg Injection?
No, there is no evidence that you need to avoid sun exposure while on Endoxan N 500mg Injection. Skin and nail discoloration are reported rarely with Endoxan N 500mg Injection.
Can Endoxan N 500mg Injection cause cancer?
Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Endoxan N 500mg Injection is high in the urinary bladder. Other rare cancers that may occur with use of Endoxan N 500mg Injection include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.
Is Endoxan N 500mg Injection chemotherapy medicine?
Yes, Endoxan N 500mg Injection is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.
Can Endoxan N 500mg Injection be used for non-cancer condition?
Yes, Endoxan N 500mg Injection can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Endoxan N 500mg Injection for nephrotic syndrome has not been established.
Can Endoxan N 500mg Injection causes weight loss?
Yes, Endoxan N 500mg Injection may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 975.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 335-38.
- Cyclophosphamide monohydrate. Camberley, Surrey: Sandoz Limited; 2014 [revised 07 Jun. 2017]. [Accessed 26 Mar. 2019] (online) Available from:
- Cyclophosphamide. Baxter Health Corporation; 1959. [Accessed 26 Mar. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 26 Mar. 2019] (online) Available from:
Expires on or after: February, 2025
A licensed vendor partner from your nearest location will deliver Endoxan N 500mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Endoxan N 500mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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1 Vial
1.0 Injection in 1 vial
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