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MD (Pharmacology), MBBS
Last updated
04 Feb 2022 | 06:54 PM (IST)

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Megaplat 100mg Injection

Prescription Required

Product introduction

Megaplat 100mg Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells.

Megaplat 100mg Injection is given as an injection into vein by a qualified medical professional.  Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, fatigue, vomiting, and diarrhea are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It may cause some serious allergic reaction, inform your doctor if you notice sore lips or mouth ulcers, rash, itching and difficulty breathing. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It makes men infertile, hence men should take doctor advice about the freezing of sperm before the treatment. You must avoid driving after taking this medicine as it may cause dizziness.

Uses of Megaplat Injection

Benefits of Megaplat Injection

In Cancer of colon and rectum

Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Megaplat 100mg Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Megaplat Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Megaplat

  • Nausea
  • Fatigue
  • Anemia (low number of red blood cells)
  • Vomiting
  • Diarrhea
  • Decreased white blood cell count (neutrophils)
  • Low blood platelets
  • Increased liver enzymes
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Stomatitis (Inflammation of the mouth)

How to use Megaplat Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Megaplat Injection works

Megaplat 100mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Megaplat 100mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Megaplat 100mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Megaplat 100mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Megaplat 100mg Injection may cause side effects which could affect your ability to drive.
Oxaliplatin_name$ treatment may result in an increased risk of dizziness, nausea, and vomiting, and other neurological symptoms that affect walking and this may affect your ability to drive.
Kidney
CAUTION
Megaplat 100mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Megaplat 100mg Injection may be needed. Please consult your doctor.
Limited information is available on the use of Megaplat 100mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.
Liver
CAUTION
Megaplat 100mg Injection should be used with caution in patients with liver disease. Dose adjustment of Megaplat 100mg Injection may be needed. Please consult your doctor.

What if you forget to take Megaplat Injection?

If you miss a dose of Megaplat 100mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Megaplat 100mg Injection
₹4293.0/Injection
₹4808/injection
12% costlier
₹6322/injection
47% costlier
₹3490/injection
19% cheaper
₹3420/injection
20% cheaper
₹5000/injection
16% costlier

Quick tips

  • Megaplat 100mg Injection is given as an injection into veins under the supervision of a doctor.

Fact Box

Chemical Class
Platinum Analogs
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Platinum compounds-Anticancer

Patient concerns

arrow
Is ulcers curable G2 stage of cancer in rectum area
Dr. Pawan Rawal
Gastroenterology
Needs evaluation Please meet a Gastro surgeon
My dad is suffering from colon cancer How to get rid of it
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Surgery is main stay of treatment, which should be followed by chemotherapy.
arrow

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1689-90.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1034-35.
  4. Oxaliplatin. Hayes, UK: Ranbaxy (UK) Limited a Sun Pharmaceutical Company; 2011 [19 Apr. 2018]. [Accessed 22 Jan. 2019] (online) Available from:External Link
  5. Oxaliplatin. Bridgewater, New Jersey: sanofi-aventis U.S; 2002 [revised Oct. 2015]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:External Link
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Megaplat 100mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Get this discount by applying coupon 1MGALL on the cart. Max. coupon discount is ₹380. T&C apply.
1.0 Injection in 1 vial
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