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Nitrogine Injection
Prescription Required
Product introduction
Nitrogine Injection is used to treat and prevent heart-related chest pain (angina) and hypertension (high blood pressure) during surgery. This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart. It has a very short-lived effect.
Nitrogine Injection is used to treat chest pain and also to promote healing of skin tear in the back passage
Nitrogine Injection is used to treat chest pain and also to promote healing of skin tear in the back passage
Uses of Nitrogine Injection
Benefits of Nitrogine Injection
In Treatment of Angina (heart-related chest pain)
Nitrogine Injection helps in prevention as well as treatment of angina. Angina is a chest pain that is usually caused by narrowing of the blood vessels which supply your heart. This means your heart does not get enough oxygen. Nitrogine Injection works quickly to relax the muscles and blood vessels in your heart so more blood (and oxygen) gets to your heart. This reduces the pain and discomfort that angina causes.
You should take this medicine at the first sign of chest pain. If the first tablet does not work, you can take a second tablet after 5 minutes. However, if your chest pain does not go away after 15 minutes, you should get urgent medical attention. This could be a sign of a heart attack. Nitrogine Injection also helps prevent chest pain if taken before exercising or doing other strenuous activities.
You should take this medicine at the first sign of chest pain. If the first tablet does not work, you can take a second tablet after 5 minutes. However, if your chest pain does not go away after 15 minutes, you should get urgent medical attention. This could be a sign of a heart attack. Nitrogine Injection also helps prevent chest pain if taken before exercising or doing other strenuous activities.
In Treatment of Hypertension (high blood pressure)
Nitrogine Injection is used to treat hypertension in hypertensive emergencies. It rapidly dilates (widens) the blood vessels. This rapid vasodilation helps reduce blood pressure levels, relieving the strain on the heart and improving blood flow to vital organs. It is typically used in critical situations where immediate blood pressure reduction is necessary, such as severe high blood pressure that can lead to organ damage or other life-threatening complications.
Side effects of Nitrogine Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nitrogine
- Blurred vision
- Decreased blood pressure
- Dizziness
- Headache
- Increased heart rate
- Lightheadedness
- Paresthesia (tingling or pricking sensation)
How to use Nitrogine Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Nitrogine Injection works
Nitrogine Injection is a nitrate. It works by improving blood supply to heart and relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload, thereby preventing/treating attacks of angina (chest pain). Relaxation of blood vessels lowers blood pressure.
Safety advice
Alcohol
UNSAFE
Consuming alcohol while taking Nitrogine Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
SAFE IF PRESCRIBED
Nitrogine Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Nitrogine Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Nitrogine Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Nitrogine Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nitrogine Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Nitrogine Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Nitrogine Injection?
If you miss a dose of Nitrogine Injection, consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- It is given via a drip into a vein under the supervision of a doctor.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- Nitrogine Injection may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- Do not consume alcohol while taking Nitrogine Injection as it may cause increased dizziness.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitrogine Injection as it may cause low blood pressure.
Fact Box
Chemical Class
Nitrates {Short acting}
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
NO Donors
Patient concerns
FAQs
Does the effect of Nitrogine Injection wear off after sometime?
Yes, excessive use of Nitrogine Injection may cause tolerance which means that Nitrogine Injection may lose its effectiveness on you. Therefore, doctors usually prescribe the smallest dose required for effective relief of acute angina attacks. Also, it is usually prescribed in morning and afternoon doses to give nitrate-free interval. Take it strictly as per the dosing interval prescribed by your doctor to prevent tolerance and maintain the effectiveness of Nitrogine Injection.
What does too much Nitrogine Injection do?
Excess Nitrogine Injection may result in low blood pressure, sweating, nausea, vomiting, headache, weak and fast pulse. It may also cause weakness, lightheadedness on standing and the patient might even faint. The patient will require emergency medical treatment in such a case.
Does Nitrogine Injection stop heart attacks?
Nitrogine Injection is prescribed to prevent attacks of heart-related chest pain (angina) in patients with coronary artery disease. In this disease, the blood vessels (coronary arteries) which supply blood to the heart become narrow because of which the heart has to work harder to get enough oxygen. Nitrogine Injection prevents angina by relaxing the blood vessels so that the heart does not have to work very hard. Also, relaxation of coronary arteries increases the oxygen supply to the heart.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 747-55.
- Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 191, 195-97.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 986-88.
- Nitroglycerin [FDA Label]. Deerfield, IL: Baxter Healthcare Corporation; 2014. [Accessed 15 Nov. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Nitroglycerin. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
- Nitroglycerin Injection [Product Information]. [Accessed 02 Aug. 2023] (online) Available from:
- Nitroglycerin Injection [FDA Label]. Shirley, NY: American Regent Laboratories Inc.; 2022. [Accessed 02 Aug. 2023] (online) Available from:
Marketer details
Name: New Medicon Pharma Labs Pvt Ltd
Address: T.T.K Road, 1st Floor, Diwan Shahib Garden, Royapettah, Chennai - 600 014.
Country of origin: India
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MRP₹90 50% OFF
1.0 Injection in 1 ampoule
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