Ondosafe Oral Solution is a medicine given to children to help treat nausea and vomiting. It is mainly given to treat nausea and vomiting associated with surgery, chemotherapy, radiotherapy, and stomach/intestinal infection. It also helps treat vomiting that is caused as a side effect of medicines like painkillers.

Ondosafe Oral Solution is used to prevent and treat nausea and vomiting.

Uses of Ondosafe Oral Solution

Benefits of Ondosafe Oral Solution

In Treatment of Nausea

Chemotherapy, radiotherapy, major surgeries, and abdominal infection put your child at risk of developing severe nausea and vomiting. It happens due to the release of a chemical called serotonin. Ondosafe Oral Solution acts by blocking the effect of this chemical and prevents nausea and vomiting. It also helps your child to recover more comfortably from these treatments. Stick to the prescribed dose, time, and way, and do not increase or decrease the dose by yourself without consulting your child’s doctor as it may result in side effects.

Side effects of Ondosafe Oral Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ondosafe

Headache
Constipation
Diarrhea
Fatigue

How to use Ondosafe Oral Solution

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Ondosafe Oral Solution may be taken with or without food, but it is better to take it at a fixed time.

How Ondosafe Oral Solution works

During radiotherapy, chemotherapy, abdominal infection, or any major surgeries, the dead cells in the body start releasing a chemical called serotonin directly into the blood. Later, this stimulates special centers in the body that are responsible for inducing vomiting in your child. Giving Ondosafe Oral Solution just before the procedure helps block the effect of this chemical on vomiting centers of the brain and prevents vomiting.

Safety advice

Alcohol

SAFE

Consuming alcohol with Ondosafe Oral Solution does not cause any harmful side effects.

Pregnancy

SAFE IF PRESCRIBED

Ondosafe Oral Solution is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Ondosafe Oral Solution is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Ondosafe Oral Solution does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Ondosafe Oral Solution is safe to use in patients with kidney disease. No dose adjustment of Ondosafe Oral Solution is recommended.

Liver

CAUTION

Ondosafe Oral Solution should be used with caution in patients with liver disease. Dose adjustment of Ondosafe Oral Solution may be needed. Please consult your doctor.

What if you forget to take Ondosafe Oral Solution?

Do not panic. Give the missed dose as soon as you remember. However, you must skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Ondosafe Oral Solution

₹17.5/Oral Solution

Vomispray

₹145/oral solution

314% costlier

Domi UP Oral Spray

Lincoln Pharmaceuticals Ltd

₹127.6/oral solution

265% costlier

Ondot Oral Solution

Glorious Biotech

₹35/oral solution

same price

Onizex Drop

Zoxvina Biotech Private Limited

₹36.96/oral solution

6% costlier

Vomijet Oral Drop

Raxon Lifesciences Pvt Ltd

₹38/oral solution

9% costlier

View all substitutes

Quick tips

Ondosafe Oral Solution effectively controls nausea and bouts of vomiting reflex in children undergoing chemotherapy or radiotherapy sessions.
It is fast-acting and starts working within 30 minutes.
Practice self-care measures:
1. Give plenty of fluids to your child to avoid dehydration
2. Avoid giving fried and spicy food or heavy meals to your child.
3. Ensure that your child eats slowly and in small proportions.

Fact Box

Chemical Class

Carbazole Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin antagonists (5-HT3 antagonists)

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Monitor temperature of Patient. If Patient has fever place a cool, damp washcloth on your child's forehead. Give your Patient a lukewarm tub bath or a sponge bath. Give a sponge bath as follows: - ? Use lukewarm water [90?F (32.2?C) to 95?F (35?C)]. Do not use cold water, ice, or rubbing alcohol, which will lower the child's body temperature too quickly. ? Sponge for 20 to 30 minutes. ? Stop if the child starts to shiver. If your child doesn't like the sponge bath or doesn't feel better after the bath, there is no need to give another one. You can use paracetamol also along with above measures to control fever till you consult Dr. will determine underlying disorders by clinical examination which range from mild conditions to the most serious of bacterial and viral illnesses and will prescribe medicines accordingly. Advice given without doing clinical examination can be imperfect or some time harmful to patient.

FAQs

What is Ondosafe Oral Solution used for?

Ondosafe Oral Solution is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, your child’s doctor may ask you to give Ondosafe Oral Solution to your child to prevent vomiting post-procedure. Apart from this, Ondosafe Oral Solution is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving Ondosafe Oral Solution to your child for a few days. Stick to the dose for best results.

What if my child takes too much Ondosafe Oral Solution?

Ondosafe Oral Solution is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Ondosafe Oral Solution can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.

How should Ondosafe Oral Solution be stored?

Ondosafe Oral Solution should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.

What all medicines should my child avoid while taking Ondosafe Oral Solution?

Usually, it is advised not to give Ondosafe Oral Solution along with antidepressant medicines, apomorphine, anti-migraine medicines, painkillers, heart medicines, and antibiotics like linezolid. But, it is ideal to speak to your child’s doctor before coming to any conclusion. So, narrate your child’s complete medical history to your child’s doctor and follow their advice strictly.

In what conditions do I need to call my child’s doctor right away?

Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.

My child is having a migraine and is on medication. Can I give Ondosafe Oral Solution along with it?

Avoid combining Ondosafe Oral Solution with such medicines because concomitant use of Ondosafe Oral Solution with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Ondansetron hydrochloride [FDA Label]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 04 Jan. 2020] (online) Available from:
Children’s Minnesota. Patient & Family Education Materials: Ondansetron (Zofran). [Accessed 04 Jan. 2020] (online) Available from:

Marketer details

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The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.