Acotrexed 100 Injection is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma.

Acotrexed 100 Injection is used to treat severe forms of a skin disease (psoriasis) and to treat several disorders of joint disorders leading to painful swelling and redness of the joints.

Uses of Acotrexed Injection

Non-small cell lung cancer
Malignant pleural mesothelioma

Benefits of Acotrexed Injection

In Non-small cell lung cancer

Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Acotrexed 100 Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Malignant pleural mesothelioma

Malignant pleural mesothelioma is a form of cancer that develops in the lungs and the inner side of the ribs. It is a very aggressive form of lung cancer. Acotrexed 100 Injection is used along with some other medicines to treat this cancer. It kills the cancer cells, and prevents the further multiplication of cancer cells. This restricts the spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and consult your doctor if you have any doubts.

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Side effects of Acotrexed Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Acotrexed

Nausea
Vomiting
Sore throat
Loss of appetite
Stomatitis (Inflammation of the mouth)
Hair loss
Low blood platelets
Rash
Fatigue
Anemia (low number of red blood cells)
Diarrhea
Decreased white blood cell count (neutrophils)
Neuropathy

How to use Acotrexed Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol

SAFE

Consuming alcohol with Acotrexed 100 Injection does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Acotrexed 100 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CAUTION

Acotrexed 100 Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

UNSAFE

Acotrexed 100 Injection may cause side effects which could affect your ability to drive.
Acotrexed 100 Injection may make you feel tired and this may affect your ability to drive.

Kidney

CAUTION

Acotrexed 100 Injection should be used with caution in patients with kidney disease. Dose adjustment of Acotrexed 100 Injection may be needed. Please consult your doctor.
Use of Acotrexed 100 Injection is not recommended in patients with moderate to severe kidney disease.

Liver

SAFE IF PRESCRIBED

Acotrexed 100 Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Acotrexed 100 Injection may not be needed in these patients. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Acotrexed 100 Injection

₹1310.0/Injection

Alimta 100mg Injection

Eli Lilly and Company India Pvt Ltd

₹6000/injection

358% costlier

Pemcure 100mg Injection

Emcure Pharmaceuticals Ltd

₹1034/injection

21% cheaper

Pemmet 100mg Injection

Intas Pharmaceuticals Ltd

₹1344.18/injection

3% costlier

Pexotra 100mg Injection

Glenmark Pharmaceuticals Ltd

₹1100/injection

16% cheaper

Pemgem 100mg Injection

Dr Reddy's Laboratories Ltd

₹1378.5/injection

5% costlier

View all substitutes

Quick tips

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Fact Box

Chemical Class

Glutamic Aacid Derivatives

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

Patient concerns

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma

Dr. Vijay Sharnangat

Medical Oncology and Hematology

This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.

Good evening, my father is suffering from lung cancer naming malignant mesothelioma. The same type of cancer my grandmother have. They both died due to this cancer disease. I want to know that is this a heridatory type of cancer? Is there is any probability in future that I will suffer from this type of cancer. Actually is their any preventive type of measures that I can follow that will help me prevent in future from suffering from cancer. Is their any tests available to keep regular updates about the trace of the cancer,

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Restrain from any addiction, have regular exercise, eat healthy food.It's not hereditary, please don't get afraid.

My father in law is a lung cancer patient.He had gone through two chemo cycles.The first one led to a significant reduction of about 50% in the tumor size.He was administered gemcitabine and carboplatin.However,the 2nd one was ineffective.Please advise as to what could be the next course of action. He was a smoker and has non-small cell carcinoma.The cancer has spread to the adrenal glands.

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

U have to do a CT SCAN 3WKS AFTER 3RD CHEMOBased on that u make assessment of response

FAQs

Is Acotrexed 100 Injection a vesicant?

No. Acotrexed 100 Injection is not a vesicant.

Is Acotrexed 100 Injection safe?

Acotrexed 100 Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Does Acotrexed 100 Injection cause hair loss?

Yes. Acotrexed 100 Injection is a prescription chemotherapy medication and hair loss is one of the possible side effects.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 946.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1077.
Pemetrexed disodium. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 10 Jan. 2019]. [Accessed 28 Jan. 2019] (online) Available from:
Pemetrexed. Indianapolis, Indiana: Lilly USA; 2004 [revised Sep. 2013]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:

Marketer details

Name: Accord Pharmaceuticals

Address: 9B, 1st Floor, Chanayak Complex, Opp Murlidhar Society, Odhav, Ahmedabad.

Country of origin: India

MRP

₹1310

Inclusive of all taxes

1.0 Injection in 1 vial

SOLD OUT

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Acotrexed 100 Injection

Product introduction

Uses of Acotrexed Injection

Benefits of Acotrexed Injection

In Non-small cell lung cancer

In Malignant pleural mesothelioma

Side effects of Acotrexed Injection

Common side effects of Acotrexed

How to use Acotrexed Injection

Safety advice

All substitutes

Quick tips

Fact Box

Patient concerns

FAQs

Is Acotrexed 100 Injection a vesicant?

Is Acotrexed 100 Injection safe?

Does Acotrexed 100 Injection cause hair loss?

Want to share the information?

Disclaimer:

References

Marketer details

Lab tests offered by us