Acoxal 50 Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells.

Acoxal 50 Injection is given as an injection into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, fatigue, vomiting, and diarrhea are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. It may cause some serious allergic reaction, inform your doctor if you notice sore lips or mouth ulcers, rash, itching and difficulty breathing. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It makes men infertile, hence men should take doctor advice about the freezing of sperm before the treatment. You must avoid driving after taking this medicine as it may cause dizziness.

Uses of Acoxal Injection

Cancer of colon and rectum

Benefits of Acoxal Injection

In Cancer of colon and rectum

Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Acoxal 50 Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Acoxal Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Acoxal

Nausea
Fatigue
Anemia (low number of red blood cells)
Vomiting
Diarrhea
Decreased white blood cell count (neutrophils)
Low blood platelets
Increased liver enzymes
Peripheral neuropathy (tingling and numbness of feet and hand)
Stomatitis (Inflammation of the mouth)

How to use Acoxal Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Acoxal Injection works

Acoxal 50 Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells which stops their growth and multiplication.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Acoxal 50 Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Acoxal 50 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Acoxal 50 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Acoxal 50 Injection may cause side effects which could affect your ability to drive.
Oxaliplatin_name$ treatment may result in an increased risk of dizziness, nausea, and vomiting, and other neurological symptoms that affect walking and this may affect your ability to drive.

Kidney

CAUTION

Acoxal 50 Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Acoxal 50 Injection may be needed. Please consult your doctor.
Limited information is available on the use of Acoxal 50 Injection in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.

Liver

CAUTION

Acoxal 50 Injection should be used with caution in patients with liver disease. Dose adjustment of Acoxal 50 Injection may be needed. Please consult your doctor.

What if you forget to take Acoxal Injection?

If you miss a dose of Acoxal 50 Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Acoxal 50 Injection

₹2661.0/Injection

Oxa 50mg Injection

₹2918.4/injection

10% costlier

Dacotin 50 Injection

Dr Reddy's Laboratories Ltd

₹3375.62/injection

27% costlier

Neoxal 50mg Injection

RPG Life Sciences Ltd

₹2800/injection

5% costlier

Oxitoz 50mg Injection

Intas Pharmaceuticals Ltd

₹3215/injection

21% costlier

Oxaltor 50mg Injection

Torrent Pharmaceuticals Ltd

₹1369.04/injection

49% cheaper

View all substitutes

Quick tips

Acoxal 50 Injection is given as an injection into veins under the supervision of a doctor.

Fact Box

Chemical Class

Platinum Analogs

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Platinum compounds-Anticancer

Patient concerns

Is ulcers curable G2 stage of cancer in rectum area

Dr. Pawan Rawal

Gastroenterology

Needs evaluation Please meet a Gastro surgeon

My dad is suffering from colon cancer How to get rid of it

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Surgery is main stay of treatment, which should be followed by chemotherapy.

Related lab tests

Carcino Embryonic Antigen

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1689-90.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1034-35.
Oxaliplatin. Hayes, UK: Ranbaxy (UK) Limited a Sun Pharmaceutical Company; 2011 [19 Apr. 2018]. [Accessed 22 Jan. 2019] (online) Available from:
Oxaliplatin. Bridgewater, New Jersey: sanofi-aventis U.S; 2002 [revised Oct. 2015]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:

Country of origin: India

MRP

₹2661

Inclusive of all taxes

1.0 Injection in 1 vial

SOLD OUT

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