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ACTEMRA 400 MG INJECTION
Prescription Required
Product introduction
ACTEMRA 400 MG INJECTION is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease). It reduces swelling in these conditions by blocking TNF alpha.
ACTEMRA 400 MG INJECTION is used to treat joint diseases leading to severe painful swelling and redness of the joints that can lead to difficulty in movement.
ACTEMRA 400 MG INJECTION is used to treat joint diseases leading to severe painful swelling and redness of the joints that can lead to difficulty in movement.
Uses of Actemra Injection
Benefits of Actemra Injection
In Treatment of Ankylosing spondylitis
Ankylosing spondylitis is a condition that mainly affects the spine. It causes severe pain and stiffness from the neck to the lower back.
ACTEMRA 400 MG INJECTION acts by lowering the activity of chemicals that causes pain and swelling. ACTEMRA 400 MG INJECTION slows down any damage caused by the disease and reduces the possibility of long-term disability.
ACTEMRA 400 MG INJECTION is a slow-acting medicine so you won’t notice an immediate effect but they’re very effective over a period of time. So it is advisable to take it as prescribed by your doctor.
ACTEMRA 400 MG INJECTION acts by lowering the activity of chemicals that causes pain and swelling. ACTEMRA 400 MG INJECTION slows down any damage caused by the disease and reduces the possibility of long-term disability.
ACTEMRA 400 MG INJECTION is a slow-acting medicine so you won’t notice an immediate effect but they’re very effective over a period of time. So it is advisable to take it as prescribed by your doctor.
In Treatment of Rheumatoid arthritis
Rheumatoid arthritis or RA is an autoimmune disorder, in which the immune system starts attacking the lining of your joints. This causes pain and swelling in the joints.
ACTEMRA 400 MG INJECTION helps treat rheumatoid arthritis. It makes the immune system function normally and prevents it from attacking the body. This gives relief from the symptoms such as pain, swelling, and stiffness in the joints. This helps in easy movement and makes you do your daily activities more easily.
You may notice some relief of joint swelling, pain, and stiffness within the first 8 weeks of treatment with ACTEMRA 400 MG INJECTION.
ACTEMRA 400 MG INJECTION helps treat rheumatoid arthritis. It makes the immune system function normally and prevents it from attacking the body. This gives relief from the symptoms such as pain, swelling, and stiffness in the joints. This helps in easy movement and makes you do your daily activities more easily.
You may notice some relief of joint swelling, pain, and stiffness within the first 8 weeks of treatment with ACTEMRA 400 MG INJECTION.
In Treatment of Psoriasis
Psoriasis is a condition where the cells in the body grow too quickly and form scales and dry, itchy patches. They can grow anywhere, but most appear on the elbows, knees, scalp, and lower back. ACTEMRA 400 MG INJECTION reduces the scaly, itchy patches which may develop on different parts of the body. It also reduces dryness associated with Psoriasis and improves skin condition. This helps boost your self-confidence and improves quality of your life. It may take several months to become fully effective. Use it exactly and for as long as it is prescribed to get the most benefit.
In Treatment of Ulcerative colitis
Ulcerative colitis is a condition that causes redness and swelling in the large intestine and the rectum (lower part of large intestine). This can cause bleeding, frequent passing of stool and stomach pain. ACTEMRA 400 MG INJECTION reduces the pain and swelling and gives you relief from these symptoms. It reduces the discomfort and helps you live your life normally.
ACTEMRA 400 MG INJECTION if taken as prescribed can prevent the return of ulcerative colitis flare (return or worsening of your symptoms). Drink plenty of fluids while taking it to make sure you stay hydrated.
ACTEMRA 400 MG INJECTION if taken as prescribed can prevent the return of ulcerative colitis flare (return or worsening of your symptoms). Drink plenty of fluids while taking it to make sure you stay hydrated.
In Treatment of Crohn’s disease
Crohn's disease is a condition that causes redness and swelling in any part of the digestive system from mouth to the anus. It can cause severe stomach pain.
ACTEMRA 400 MG INJECTION works by blocking chemicals causing pain and swelling. Thereby giving relief and helping you to live a normal life. This medicine is given as an injection. You should always take it as it has been prescribed for you.
ACTEMRA 400 MG INJECTION works by blocking chemicals causing pain and swelling. Thereby giving relief and helping you to live a normal life. This medicine is given as an injection. You should always take it as it has been prescribed for you.
Side effects of Actemra Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Actemra
- Headache
- High blood pressure
- Upper respiratory tract infection
- Injection site reactions (pain, swelling, redness)
How to use Actemra Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Safety advice
Alcohol
SAFE
Consuming alcohol with ACTEMRA 400 MG INJECTION does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
ACTEMRA 400 MG INJECTION may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
ACTEMRA 400 MG INJECTION is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
ACTEMRA 400 MG INJECTION may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
ACTEMRA 400 MG INJECTION should be used with caution in patients with kidney disease. Dose adjustment of ACTEMRA 400 MG INJECTION may be needed. Please consult your doctor.
Limited information is available on the use of ACTEMRA 400 MG INJECTION in patients with moderate to severe kidney disease. No dose adjustment is required in patients with mild kidney disease.
Limited information is available on the use of ACTEMRA 400 MG INJECTION in patients with moderate to severe kidney disease. No dose adjustment is required in patients with mild kidney disease.
Liver
CAUTION
ACTEMRA 400 MG INJECTION should be used with caution in patients with liver disease. Dose adjustment of ACTEMRA 400 MG INJECTION may be needed. Please consult your doctor.
Use of ACTEMRA 400 MG INJECTION is not recommended in patients with active liver disease.
Use of ACTEMRA 400 MG INJECTION is not recommended in patients with active liver disease.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- ACTEMRA 400 MG INJECTION is given as a drip (intravenous infusion) or as an injection directly into a vein.
- You may be asked for regular blood tests to check blood counts, cholesterol level and liver functioning during the treatment.
- It might make you feel dizzy. If this happens, avoid driving or operating on machinery.
- It makes it hard to fight with an infection. Inform your doctor if you notice fever, cough or stomach pain.
- Inform your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
- Do not stop taking medicine without talking to your doctor first.
Fact Box
Chemical Class
Monoclonal antibody (mAb)
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Biologics
Patient concerns
FAQs
Who should be treated with ACTEMRA 400 MG INJECTION?
ACTEMRA 400 MG INJECTION should be given for treating patients suffering from moderate to severe Covid-19 infection who have persistent reduction in their oxygen levels (a condition called hypoxia) that continues to get worse. The hypoxia may continue to get worsened even after 24 to 48 hours of treatment with corticosteroids and supportive care.
Is ACTEMRA 400 MG INJECTION recommended for all Covid-19 patients? If not, why?
No, ACTEMRA 400 MG INJECTION is not recommended for all Covid-19 patients. This is because ACTEMRA 400 MG INJECTION has its own potential health hazards. ACTEMRA 400 MG INJECTION can lead to persistent serious infection and prolonged multiplication and shedding of the virus causing infection, so, it must be given only if the benefits outweigh the risks involved.
What are the side effects of ACTEMRA 400 MG INJECTION?
The potential side effects of ACTEMRA 400 MG INJECTION include anaphylaxis (serious allergic reaction) with infusion, transaminitis (very high levels of liver enzymes due to which they start moving into the bloodstream), leukopenia (a condition where a person has reduced white blood cells and hence increased risk for infections) and neutropenia (a condition where a person has abnormally low number of cells called neutrophils, that fight infections in our body). Some other side effects are risk of serious bacterial infections, viral infections and reactivation of tuberculosis (TB) virus.
Who should not be given ACTEMRA 400 MG INJECTION?
ACTEMRA 400 MG INJECTION should not be given to patients who have or ever had abnormal levels of liver enzymes (transaminitis), platelet counts (<50000), or if they have TB, or any active bacterial or viral infection. The use of ACTEMRA 400 MG INJECTION is contraindicated in pregnancy and breastfeeding mothers too, owing to its risk of developing serious complications.
What to do if there is no improvement seen after giving ACTEMRA 400 MG INJECTION too?
Your doctor will decide the next course of action if there is no improvement seen even after giving ACTEMRA 400 MG INJECTION. ACTEMRA 400 MG INJECTION will prevent inflammation of the lungs but will not cure the damage already done due to the existing disease. Recovery of the lungs takes time to improve. Persistent breathlessness after ACTEMRA 400 MG INJECTION administration requires further evaluation of patients for other lung-related issues (pulmonary intravascular coagulopathy) or heart-related problems (cardiac dysfunctions). Any other bacterial infections that might have occurred should also be treated separately.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Medscape. Tocilizumab. [Accessed 02 Apr. 2019] (online) Available from:
- Tocilizumab. South San Francisco, California: Genentech, Inc. [Accessed 30 Jan. 2019] (online) Available from:
Marketer details
Name: Roche Products India Pvt Ltd
Address: 1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051
Country of origin: India
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