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Written By
Dr. Shreya Gupta
MDS (Oral Pathology & Microbiology), BDS
Reviewed By
Dr. Shilpa Garcha
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Home>Actilyse>actilyse 50mg injection

Actilyse 50mg Injection

Prescription Required
Marketer
Boehringer Ingelheim
SALT COMPOSITION
Alteplase (50mg)
Salt Synonyms
Recombinant tissue plasminogen activator

Product introduction

Actilyse 50mg Injection is a medicine which dissolves the clots that have formed in blood vessels. It is used to treat stroke, heart attack, and pulmonary embolism (blood clots in the lungs). It is known as a thrombolytic or “clot-busting” medicine.

It is a thrombolytics

Uses of Actilyse Injection

Benefits of Actilyse Injection

In Treatment of Heart attack

Actilyse 50mg Injection dissolves harmful blood clots that cause heart attack (if they are in the heart). They also dissolve clots that form in other blood vessels. This means that blood can again start to flow freely through your body. This medicine will, therefore, reduce both the damage caused by, and the risk of dying from a heart attack. The sooner the injection is given, the greater are the chances of recovery.

In Treatment of Ischemic stroke

Actilyse 50mg Injection is sometimes called a “clot-buster” because it dissolves harmful blood clots that cause strokes (if they are in the brain). This helps the blood flow freely around your body thereby reducing the damage caused by and the future risk of stroke. It should be given as soon as possible after the onset of stroke.

In Treatment of Pulmonary embolism

Pulmonary embolism refers to clotting of blood in your lungs. Actilyse 50mg Injection prevents this clot formation in your lungs. This helps the blood flow freely around your body thereby preventing a heart attack or stroke. It prevents the formation of blood clots and also prevents the existing ones from growing bigger in size. Make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Actilyse Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Actilyse

  • Bleeding
  • Nausea
  • Vomiting
  • Confusion

How to use Actilyse Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Actilyse 50mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Actilyse 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Actilyse 50mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
NOT RELEVANT
Not relevant, as Actilyse 50mg Injection is intended for use in hospitalised patients.
Kidney
SAFE IF PRESCRIBED
Actilyse 50mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Actilyse 50mg Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Actilyse 50mg Injection in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • It should be given as soon as possible (within 12 hours) after the onset of a heart attack or within 4.5 hours of onset of stroke.
  • Let your doctor know immediately if you develop any nosebleeds, gum bleeding, black or tarry stools, or bruising. 
  • Do not discontinue the medicines started after this injection as it may increase your chances of having another heart attack or stroke.

Fact Box

Chemical Class
Carboxylic Acids Derivatives
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Plasminogen Activators- Thrombolytics

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User feedback

FAQs

How is Actilyse 50mg Injection administered?

Actilyse 50mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Actilyse 50mg Injection.

Is Actilyse 50mg Injection safe?

Actilyse 50mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Can the use of Actilyse 50mg Injection increase the risk of bleeding?

Yes, Actilyse 50mg Injection can increase the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

What medicines should I avoid while taking Actilyse 50mg Injection?

Actilyse 50mg Injection can interact with several medicines. If you are already taking Actilyse 50mg Injection, do not take any other medicine without talking to your doctor.

When will I feel better after taking Actilyse 50mg Injection?

Actilyse 50mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Actilyse 50mg Injection. This does not mean that the medicine is not working, therefore keep taking this medicine as prescribed.
Related lab tests
  • Platelet Count

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    Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

    References

    1. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 866.
    2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 45-47.
    3. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 382.
    4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Alteplase. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:External Link

    Marketer details

    Name: Boehringer Ingelheim
    Address: 1102, Hallmark Business Plaza, 11th Floor, Gurunanak Hospital Road, Near Gurunanak Hospital, Bandra (East), Mumbai 400051
    Country of origin: Germany
    Expires on or after: February, 2025

    A licensed vendor partner from your nearest location will deliver Actilyse 50mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

    In case of any issues, contact us

    Email ID: [email protected]
    Phone Number: 0124-4166666
    Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
    ₹49519₹49899Get 1% OFF
    ₹48727+ free shipping withCare Plan Logo
    Inclusive of all taxes
    Get this discount by applying coupon 1MGALL on the cart. Max. coupon discount is ₹380. T&C apply.
    1 Vial
    1.0 Injection in 1 vial
    Add to cart
    Not returnable Read policy

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