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PhD (Pharmacology), PGDPRA
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MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Addbactam 2gm Injection


Product introduction

Addbactam 2gm Injection is used in combination with other antibiotics for the treatment of various types of serious bacterial infections such as pneumonia, skin and soft tissue infections, urinary tract infections, and others.

Addbactam 2gm Injection is a beta-lactamase inhibitor. It works by blocking an enzyme (beta lactamase) produced by bacteria to inactivate antibiotics. This reduces resistance and enhances the activity of antibiotics against bacteria.

Uses of Addbactam Injection

  • Severe bacterial infections

Benefits of Addbactam Injection

In Severe bacterial infections

Addbactam 2gm Injection works by killing bacteria which can cause serious infections. It is used to treat many different types of bacterial infections such as infections of lungs (pneumonia) and urinary tract. It is given by a doctor or nurse into a vein and should not be self-administered. Addbactam 2gm Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Addbactam Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Addbactam

  • Injection site pain
  • Diarrhea

How to use Addbactam Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Addbactam Injection works

Addbactam 2gm Injection is a beta-lactamase inhibitor. It works by blocking an enzyme called beta lactamase produced by bacteria to inactivate antibiotics. Addbactam 2gm Injection is frequently combined with beta-lactam antibiotics, such as ampicillin, cefoperazone, meropenem. As a single medicine, it treats infection caused by a type of bacterium called Acinetobacter baumanii. This activity is mediated by its interaction with certain proteins.

Safety advice

Alcohol
SAFE
Consuming alcohol with Addbactam 2gm Injection does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Addbactam 2gm Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Addbactam 2gm Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Addbactam 2gm Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Addbactam 2gm Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Addbactam 2gm Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Addbactam Injection?

If you miss a dose of Addbactam 2gm Injection, consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Addbactam 2gm Injection
₹499.0/Injection
₹702.01/injection
41% costlier
₹428.57/injection
14% cheaper
₹750/injection
50% costlier

Quick tips

  • Addbactam 2gm Injection is used in treatment of severe bacterial infections, in combination with certain antibiotics. 
  • It is also used alone in the treatment of serious infections caused by pathogen Acinetobacter baumannii including those resistant to other antibiotics.
  • It is preferentially given as an injection directly into a vein over a period of 15-60 minutes.
  • When used alone, it is associated with few adverse effects, mainly pain at the injection site and diarrhea.

Fact Box

Chemical Class
Alpha amino acids derivatives
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Cell wall active agent - Penicillin:Beta-lactamase inhibitors

Patient concerns

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Scar on face due to bacterial infections
Dr. Atul Jain
Dermatology
Pic is not clear, plz visit for proper opinion
I have a history of recurring yeast and bacterial vaginosis infections.
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days
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FAQs

Why is Addbactam 2gm Injection added to other antibiotics?

Addbactam 2gm Injection added to other antibiotics like ampicillin, cefoperazone, etc., because Addbactam 2gm Injection contains Sulbactam, a beta-lactamase inhibitor, which reduces resistance and enhances the activity of other antibiotics like ampicillin, cefoperazone, etc., against the bacteria.

Who should not take Addbactam 2gm Injection?

Addbactam 2gm Injection should not be taken by an individual if he/she had an allergic reaction to ampicillin, sulbactam, or any penicillin antibiotic (such as penicillins or cephalosporins), or if he/she has a history of liver problems caused by ampicillin/sulbactam.

What should I discuss with my doctor before receiving Addbactam 2gm Injection?

Before taking Addbactam 2gm Injection, you should tell your doctor if you have ever had an allergic reaction to Addbactam 2gm Injection or any similar medicine. Inform the doctor if you have any type of allergy, asthma or breathing problems, heart disease or kidney disease. Let your doctor know about all the medicines that you may be taking as they may affect or be affected by Addbactam 2gm Injection. Pregnant or breastfeeding mothers should also seek their doctor’s advice before taking Addbactam 2gm Injection.

Can I use a discolored solution of Addbactam 2gm Injection?

No. You should not use Addbactam 2gm Injection if the medicine has changed colors or has particles in it. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better, that you discard the solution and go for another vial.

I feel better now. Can I stop taking Addbactam 2gm Injection?

No. Make sure to receive all doses your doctor has prescribed, even if you feel better. This is because your symptoms may have improved but chances are that the infection is still present in your body. Skipping doses can increase the risk of developing an infection that is resistant to medication. So, continue taking Addbactam 2gm Injection as prescribed. After you have finished all the doses, your doctor may advise you on some tests to make sure your infection has completely cleared up.

Does Addbactam 2gm Injection treat the flu?

No. Addbactam 2gm Injection does not treat a viral infection such as the flu or a common cold.
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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Petri WA Jr. Penicillins, Cephalosporins, and Other β -Lactam Antibiotics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1501.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1293-94.
  3. Sulbactam. [Accessed 28 Mar. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 29 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Fusion Healthcare Pvt Ltd
Address: Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034
Country of origin: India

MRP
499
Inclusive of all taxes
1.0 Injection in 1 vial
SOLD OUT
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