Amifrus 20mg/50mg Tablet is a combination of two medicines used to reduce excess fluid levels in the body while maintaining the potassium balance. It is used to treat edema (fluid overload) and some cases of hypertension.

Amifrus 20mg/50mg Tablet is a combination of potassium sparing and high ceiling diuretic medicines.

Uses of Amifrus Tablet

Treatment of Edema

Benefits of Amifrus Tablet

In Treatment of Edema

Edema is caused by your body retaining too much water. Amifrus 20mg/50mg Tablet helps get rid of the extra water and electrolytes from your body by increasing the amount of urine produced. This enables your body to get rid of extra water thereby relieving symptoms such as shortness of breath and swelling in your arms, legs, or abdomen. Therefore, you can carry out your daily activities more comfortably. Take Amifrus 20mg/50mg Tablet regularly without skipping any doses. Make appropriate lifestyle changes, like losing weight (if you are overweight), exercise daily, and eat a healthy diet to get maximum benefits.

Side effects of Amifrus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amifrus

Breast enlargement in male
Electrolyte imbalance
Volume depletion

How to use Amifrus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amifrus 20mg/50mg Tablet is to be taken with food.
Avoid Amifrus 20mg/50mg Tablet with dietary sodium.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Amifrus 20mg/50mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Amifrus 20mg/50mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Amifrus 20mg/50mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Amifrus 20mg/50mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Amifrus 20mg/50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Amifrus 20mg/50mg Tablet may be needed. Please consult your doctor.
Use of Amifrus 20mg/50mg Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Amifrus 20mg/50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Amifrus 20mg/50mg Tablet may be needed. Please consult your doctor.

What if you forget to take Amifrus Tablet?

If you miss a dose of Amifrus 20mg/50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Amifrus 20mg/50mg Tablet

₹4.5/Tablet

Lasilactone 50 Tablet

Sanofi India Ltd

₹2.44/tablet

42% cheaper

Fruselac Tablet

Lupin Ltd

₹2.38/tablet

43% cheaper

Spiromide Tablet

RPG Life Sciences Ltd

₹3.69/tablet

12% cheaper

Amifru-S Tablet

Torrent Pharmaceuticals Ltd

₹1.35/tablet

68% cheaper

Aldoloc 20 mg/50 mg Tablet

Thrift Pharmaceuticals

₹2.5/tablet

40% cheaper

View all substitutes

Quick tips

Amifrus Tablet

Amifrus 20mg/50mg Tablet helps removes excess water from your body.
Take it in the morning with breakfast to avoid getting up at night to urinate.
It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
It may cause excessive urine production, dehydration, and low electrolyte levels. Notify your doctor if you experience dizziness, tiredness, or muscle weakness that doesn't go away.
Your doctor may regularly monitor your blood pressure, kidney function and the level of salts such as potassium and sodium in your blood while you're taking this medication.

Fact Box

Habit Forming

Therapeutic Class

CARDIAC

Patient concerns

My grandmother is PATIENT PATIENT she is an heart patients also she has asthma. But now her leg is too thick. I think she has deep vein thrombosis diseases. So sir please advise me what thing to do

Dr. Nabajit Talukdar

Interventional Cardiology

Show her to a cardiologist probably fluid exceesss n edema

Diabetic macular edema treatment

Dr. Richa Jain

Ophthalmology

Laser or antivegf injection

FAQs

Amifrus Tablet

What are the recommended storage conditions for Amifrus 20mg/50mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

What are the contraindications associated with the use of Amifrus 20mg/50mg Tablet?

The use of Amifrus 20mg/50mg Tablet should be avoided in patients with hypersensitivity to furosemide, sulfonylureas or spironolactone or any other ingredient of the product. The use of this medicine should also be avoided in patients with anuria, acute renal insufficiency, hepatic coma and pre-coma, low blood pressure (hypotension), cardiac arrhythmias, patients taking aminoglycosides or cephalosporins, kidney dysfunction due to drugs which cause renal damage, patients with high potassium levels (hyperkalemia), Addison's disease and in children with moderate to severe renal impairment.

What is Amifrus 20mg/50mg Tablet?

Amifrus 20mg/50mg Tablet is a fixed-dose combination of furosemide (a loop diuretic) and spironolactone (an antagonist of aldosterone). Both are diuretics and they help to remove excess fluid from the body. The use of this combination is advised in patients of congestive heart failure (heart failure leading to fluid accumulation in the lung and rest of the body), nephrotic syndrome (a kidney disorder), liver cirrhosis with fluid retention (edema) and swelling of the abdomen (ascites).

Is it safe to use Amifrus 20mg/50mg Tablet?

Yes, Amifrus 20mg/50mg Tablet is safe for most of the patients. However, in some patients it may cause common side effects like dizziness, dehydration, decreased sodium level in blood, breast enlargement in males, decreased magnesium level in blood, decreased calcium level in blood, increased blood uric acid. Inform your doctor if you experience any persistent problem while taking this medicine.

Can the use of Amifrus 20mg/50mg Tablet cause dizziness?

Yes, the use of Amifrus 20mg/50mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better. Do not drive or use any machines.

Can the use of Amifrus 20mg/50mg Tablet cause gout?

Yes, Amifrus 20mg/50mg Tablet can cause gout. Amifrus 20mg/50mg Tablet contains furosemide which can increase the blood uric acid levels by increasing its absorption from the kidneys. Increased uric acid levels can cause a gout attack. Inform your doctor if you have hyperuricemia (excess of uric acid in blood) or a history of gout before taking this medicine. Use of Amifrus 20mg/50mg Tablet should be avoided in patients with gout.

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References

Lactomide. [Accessed 11 Apr. 2019] (online) Available from:

Marketer details

Name: Elder Pharmaceuticals Ltd

Address: “Elder House” Plot No. C-9, Dalia Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai – 400053.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.