Axzyb Tablet is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.

Side effects of Axzyb Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Axzyb

High blood pressure
Joint pain
Loss of appetite
Diarrhea
Breathing problems
Abdominal pain
Constipation
Cough
Decreased appetite
Decreased level of thyroid hormones
Difficulty in speaking
Dry skin
Indigestion
Headache
Nausea
Pain in extremities
Painful blisters on hands and feet
Protein in urine
Rash
Breathlessness
Stomatitis (Inflammation of the mouth)
Taste change
Vomiting

How to use Axzyb Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Axzyb Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Axzyb Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Axzyb Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Axzyb Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Axzyb Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Axzyb Tablet is safe to use in patients with kidney disease. No dose adjustment of Axzyb Tablet is recommended.

Liver

CAUTION

Axzyb Tablet should be used with caution in patients with liver disease. Dose adjustment of Axzyb Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Axzyb Tablet in patients with the severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Axzyb Tablet

₹1.35/Tablet

Raxitinib 5mg Tablet

Medicamen Biotech Ltd

₹154.71/tablet

1427% costlier

Inlybest 5mg Tablet

Aprazer Healthcare Pvt Ltd

₹10.13/tablet

same price

Inlyta 5mg Tablet

Pfizer Ltd

₹2444.61/tablet

24032% costlier

Aximac Tablet

Admac Pharma Ltd

₹89.97/tablet

788% costlier

Axinib 5mg Tablet

AMPS Biotech Pvt Ltd

₹446.43/tablet

4307% costlier

Quick tips

Take it with or without food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Fact Box

Chemical Class

Enzamide and Indazole Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine kinase inhibitors

Patient concerns

Metastatic kidney cancer stage 4

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Thanks for reaching out to meHe has progressive disease on sorafenib

Kidney cancer solution & medison stage detail not clear detail

Dr. Vijay Sharnangat

Medical Oncology and Hematology

I don't know why but I am not able to see your downloaded reports, so please type your reports by only conclusion.

FAQs

What are the possible signs and symptoms of kidney cancer?

Some possible signs and symptoms of kidney cancer include blood in the urine (hematuria) which may appear dark red, orange, or pink. As kidney cancer progresses, it may produce other symptoms such as persistent pain, pressure just below the ribs, or intense fatigue.

How long should I take the Axzyb Tablet?

The duration of treatment varies from person to person. Your doctor will decide treatment duration based on your condition, response to treatment, and tolerance to side effects. Your doctor may decrease your dose or stop your treatment temporarily or permanently if you experience side effects.

When should I call my doctor right away?

Get medical help right away if you have signs of allergic reaction such as rash, hives, itching, and blisters. Also, let your doctor know if you notice bleeding or blood in your cough, very high blood pressure, signs of thyroid problems such as a change in weight, nervousness, restlessness, weakness, thinning of hair after taking Axzyb Tablet. Also, if you feel sudden mood changes, fast heart rate, change in voice, fever, or chills, visit your doctor without delay.

What lab tests are important before starting Axzyb Tablet?

Your doctor may advise you to undergo lab or medical tests such as blood pressure, thyroid function, kidney function, liver or pancreatic function tests, complete blood counts, urine tests, blood mineral levels including sodium or potassium before starting this medication. Women of childbearing age should have a pregnancy test before starting this medicine.

Who should not take the Axzyb Tablet?

People who are allergic to axitinib or any other ingredient of this medicine should not take Axzyb Tablet. Talk to your doctor if you are not sure.

Does Axzyb Tablet affect fertility?

Yes, this medicine may cause fertility issues in males as well as females. Talk to your doctor before starting your treatment to know about ways to preserve fertility.

I feel exhausted after starting treatment with Axzyb Tablet. What should I do?

General tiredness/fatigue is a common side effect experienced during treatment with Axzyb Tablet. You may need to adjust your schedule to manage fatigue. Take ample amounts of rest and do not indulge in physically exhausting activities. Exercise, such as walking, can help cope up with fatigue.

How do I know if I have developed thyroid problems after taking Axzyb Tablet?

Regular monitoring of thyroid function is recommended before as well as during your treatment with Axzyb Tablet. Your doctor will advise blood tests to assess the same. Tell your doctor if you have symptoms such as feeling more tired than usual, weight gain or loss, sensitivity to hot or cold weather, hair loss, voice changes (such as deepening of the voice), muscle cramps, and aches.

What is Reversible Posterior Leukoencephalopathy Syndrome?

Reversible Posterior Leukoencephalopathy Syndrome (RPLS) is a rare but serious neurological complication associated with the use of Axzyb Tablet. It is characterized by symptoms such as headaches, vision problems, mental changes, seizures, high blood pressure, weakness, and swelling in the brain. This condition is reversible and symptoms subsides once treated. Consult your doctor right away if you experience any of these worrisome episodes while taking Inlyta tablets.

I have swelling in my ankles and feet after I started taking Axzyb Tablets? What does this mean?

This medicine may cause side effects such as excessive tiredness, swelling of the abdomen, legs, or ankles, shortness of breath, or protruding neck veins. These are alarming and indicate chances of developing heart failure. The use of Axzyb Tablet is associated with an increased risk of heart failure events and these symptoms must therefore be taken seriously and addressed at the earliest. Tell your doctor without any delay if you notice any of these episodes.

How can I store Axzyb Tablet at home?

Store the medicine at room temperature at a dry place beyond the reach of the children and pets to avoid any accidental intake.

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Related lab tests

Complete Blood Count

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 111-12.
Axitinib. Sandwich, Kent: Pfizer Limited; 2012 [revised Nov. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
Axitinib. New York, New York: Pfizer Inc.; 2012 [revised Aug. 2014]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Marketer details

Name: Glenmark Pharmaceuticals Ltd

Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.