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MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Azadine-O Tablet


Product introduction

Azadine-O Tablet is used in the treatment of some kinds of blood cancer. It is used for the treatment of adult patients with all subtypes of Myelodysplastic Syndrome (MDS). It may be also used to treat other conditions, as determined by the doctor.

Azadine-O Tablet is used to treat severe forms of a skin disease (psoriasis) and to treat several disorders of joint disorders leading to painful swelling and redness of the joints.

Benefits of Azadine-O Tablet

In Blood cancer

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Azadine-O Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Treatment of Myelodysplastic syndrome

Azadine-O Tablet is used to treat myelodysplastic syndrome, a group of conditions in which the bone marrow produces blood cells that are abnormal in structure and function, and does not produce enough healthy blood cells. Azadine-O Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Azadine-O Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Azadine-O

  • Vomiting
  • Weakness
  • Nausea
  • Decreased potassium level in blood
  • Bruise
  • Fever
  • Chills
  • Diarrhea
  • Constipation

How to use Azadine-O Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Azadine-O Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Azadine-O Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Azadine-O Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Azadine-O Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Azadine-O Tablet may cause side effects which could affect your ability to drive.
Azadine-O Tablet can cause side effects such as tiredness and this may affect your ability to drive.
Kidney
CAUTION
Azadine-O Tablet should be used with caution in patients with kidney disease. Dose adjustment of Azadine-O Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Azadine-O Tablet should be used with caution in patients with liver disease. Dose adjustment of Azadine-O Tablet may be needed. Please consult your doctor.
Use of Azadine-O Tablet is not recommended in patients with advanced liver cancer.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Azadine-O Tablet
₹1428.57/Tablet
Xpreza 300mg Tablet
Natco Pharma Ltd
₹1571.43/tablet
10% costlier
Azashine 300mg Tablet
Hetero Healthcare Limited
₹1571.43/tablet
10% costlier
Azacytin 300mg Tablet
Dr Reddy's Laboratories Ltd
₹1421.43/tablet
1% cheaper
MDS-O 300mg Tablet
Adley Formulations
₹1030/tablet
28% cheaper

Quick tips

  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Fact Box

Chemical Class
Pyrimidine Nucleoside Analogue
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites

Patient concerns

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My PATIENT having cancer in urinary bladder, now it is removed and histopathology lab report says the disease is not there any more in body no kemo is required. But the further medicine given for 3 month are very costly which are only for vitamin. Need the genuine ans and generic medicine. As there is no condition to take so much expensive medicine. Bcoz operation has done with the help of charity and trust.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Yes o please share details
I m feeling itching n pain on skin rolled over from penis while intercourse unrinal infection plz suggest best tablet to cure it.
Dr. Pranay Gandhi
Sexology
tablet zifi-o 1 bd for 5 days
arrow

FAQs

Is Azadine-O Tablet a vesicant?

Azadine-O Tablet is not a vesicant and is not known to cause severe local tissue damage upon extravasation (leaking of injected Azadine-O Tablet into the surrounding tissues from the site of administration) when injected

Does Azadine-O Tablet cause hair loss?

No, Azadine-O Tablet is not known to cause hair los

Is Azadine-O Tablet chemotherapy?

Yes. Azadine-O Tablet is chemotherapy and a cytotoxic drug used in the treatment of various cancers. It is toxic to cancer cells and interferes with the cell's DNA synthesis, thus slowing down or stopping its growth and multiplication (cytotoxic effect)

Is Azadine-O Tablet a cytotoxic drug?

Yes. Azadine-O Tablet is a cytotoxic drug.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1700.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 112-13.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India

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14.0 tablets in 1 bottle
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