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Celonib 100mg Capsule
Prescription Required
Product introduction
Celonib 100mg Capsule belongs to the class of medicines known as tyrosine kinase inhibitors. It is used in the treatment of blood cancer (chronic myeloid leukaemia and Acute lymphocytic leukemia) and gastrointestinal stromal tumor.
Celonib 100mg Capsule should be taken with food, but better to have it same time every day to get the most benefit. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include edema, nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue, and abdominal pain. Let your doctor know if you experience unexpected rapid weight gain. Your doctor may advise for regular monitoring of blood cells and liver function while you are taking this medicine. Do not drive or do anything requiring mental focus if you experience dizziness and blurry vision.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Celonib 100mg Capsule should be taken with food, but better to have it same time every day to get the most benefit. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include edema, nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue, and abdominal pain. Let your doctor know if you experience unexpected rapid weight gain. Your doctor may advise for regular monitoring of blood cells and liver function while you are taking this medicine. Do not drive or do anything requiring mental focus if you experience dizziness and blurry vision.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Celonib Capsule
- Blood cancer (Chronic myeloid leukaemia)
- Blood cancer (Acute lymphocytic leukemia)
- Gastrointestinal stromal tumour
Benefits of Celonib Capsule
In Blood cancer (Chronic myeloid leukaemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Celonib 100mg Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Blood cancer (Acute lymphocytic leukemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Celonib 100mg Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Gastrointestinal stromal tumour
A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs most commonly in the stomach or small intestine. The tumors develop into the specialized cells called interstitial cells of Cajal (ICCs). Celonib 100mg Capsule helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit.
Side effects of Celonib Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Celonib
- Edema (swelling)
- Nausea
- Vomiting
- Muscle cramp
- Musculoskeletal (bone, muscle or joint) pain
- Diarrhea
- Rash
- Fatigue
- Abdominal pain
How to use Celonib Capsule
Take this medicine in the dose and duration as advised by your doctor. Celonib 100mg Capsule is to be taken with food.
How Celonib Capsule works
Celonib 100mg Capsule is an anti-cancer medication. A protein enzyme, bcr-abl tyrosine kinase, responsible for the growth of abnormal proliferation of cancer cells. This medicine inhibits the proliferation and induces apoptosis (planned cell death) in bcr-abl positive cells (cancer cells). This is how it works to stop or slow the spread of cancer.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Celonib 100mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Celonib 100mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Celonib 100mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Lactating women should not breastfeed while using this drug and one month after stopping it.
Lactating women should not breastfeed while using this drug and one month after stopping it.
Driving
UNSAFE
Celonib 100mg Capsule may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Celonib 100mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Celonib 100mg Capsule may be needed. Please consult your doctor.
Liver
CAUTION
Celonib 100mg Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Celonib 100mg Capsule may be needed. Please consult your doctor.
What if you forget to take Celonib Capsule?
If you miss a dose of Celonib 100mg Capsule, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Always take it with food and a full glass of water to prevent nausea.
- It may cause dizziness or blurred vision. Do not drive or do anything requiring concentration until you know how it affects you.
- Water retention and swelling are very common side effects of Celonib 100mg Capsule. Notify your doctor if you have unexpected rapid weight gain.
- Do not change the dose or discontinue use without consulting your doctor.
- Notify your doctor about all the medications you are taking, including over the counter medicines and dietary supplements.
- Your doctor may get regular blood tests done to monitor your liver function and the number of blood cells in your blood.
Fact Box
Chemical Class
Benzanilides Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Tyrosine kinase inhibitors
Patient concerns
FAQs
Can Celonib 100mg Capsule be taken with food?
Yes, the best way to take it is with a glass of water and food. This prevents irritation in the food pipe and stomach. If you cannot swallow it, put the tablets in a glass of water or apple juice (approximately 50 ml for a 100 mg tablet and 200 ml for a 400 mg tablet). Stir it with a spoon to make it uniform and drink it immediately.
Is it safe to drive while taking Celonib 100mg Capsule?
Celonib 100mg Capsule may cause dizziness, lightheadedness or drowsiness in some people. Make sure you know how you react to it before you drive a car or operate machinery.
What precautions need to be followed while taking Celonib 100mg Capsule?
While taking Celonib 100mg Capsule, make sure you follow all the instructions given by your doctor, carefully and keep all appointments. You will need regular follow-up to ensure that the treatment is working. Regular blood tests, weight checks, and urine tests may be required to find out any side effects before it becomes serious. Make sure you use a method of contraception to prevent pregnancy during treatment with Celonib 100mg Capsule. Tell your doctor immediately if you become pregnant while you are taking this medicine. If you are about to start taking any new medicine, remind your doctor that you are taking Celonib 100mg Capsule.
Ever since I started using Celonib 100mg Capsule, I have noticed that I develop rashes and severe itching when I have sun exposure. Is it because of the medicine or the disease?
This medicine may make your skin much more sensitive to sunlight than it normally is. Exposure to sunlight may cause skin rash, itching, redness or severe sunburn. When you are outdoors, wear protective clothing and use a sunscreen with an SPF of 15 or higher. If you feel a burning sensation on your skin, tell your doctor.
The doctor has advised me not to take any medicine on my own while taking Celonib 100mg Capsule. Should I consult my doctor even if I need to take paracetamol for my fever?
Yes, there are a number of medicines which interfere with Celonib 100mg Capsule, including paracetamol. Therefore you should not self medicate while taking Celonib 100mg Capsule. Other medicines which interfere with Celonib 100mg Capsule include cyclosporin, dexamethasone (a steroid), warfarin, antiviral medicines which treat AIDS and some medicines which treat bacterial infections, high cholesterol, high blood pressure, heart problems, and mental disorders and depression. Consult your doctor before taking any medicine, and inform him that you are on Celonib 100mg Capsule therapy.
What precautions need to be followed while taking Celonib 100mg Capsule?
While taking Celonib 100mg Capsule, make sure you follow all the instructions given by your doctor, carefully and keep all appointments. You will need regular follow-up to ensure that the treatment is working. Regular blood tests, weight checks, and urine tests may be required to find out any side effects before it becomes serious. Make sure you use a method of contraception to prevent pregnancy during treatment with Celonib 100mg Capsule. Tell your doctor immediately if you become pregnant while you are taking this medicine. If you are about to start taking any new medicine, remind your doctor that you are taking Celonib 100mg Capsule.
Can I expect that if I take Celonib 100mg Capsule regularly and as advised by the doctor for CML, I will be cured?
Celonib 100mg Capsule has proved effective in many cases of CML. It is also noticed that the chances of survival increase after taking this medicine. The doctor who is treating CML can tell you better. The doctor will analyze your current state, blood test results, response to treatment, any other medical illness which you may be having, etc. and tell you.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1732-34.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 953.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 692-94.
- Imatinib mesylate. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2001 [revised Jan 2012]. [Accessed 23 Jan. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Imatinib. [Updated 2018 Oct 31]. [Accessed 18 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:
Country of origin: India
Expires on or after: February, 2025
A licensed vendor partner from your nearest location will deliver Celonib 100mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: February, 2025
A licensed vendor partner from your nearest location will deliver Celonib 100mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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