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Combe Five Suspension for Injection


Product introduction

Combe Five Suspension for Injection is a 5 in 1 vaccine given to infants and young children. It provides active immunization against five severe diseases namely Diphtheria, Haemophilus influenzae type b, Hepatitis-B, Pertussis, and Tetanus. It boosts the immune system and produces protective antibodies against these diseases.

Combe Five Suspension for Injection is to be administered by your child’s doctor only. It is injected into the thigh muscles of infants. In older children, the vaccine is administered into the arm muscle. It is administered in 3 doses, each 4 weeks apart, preferably before the age of 6 months. Generally, it is recommended to administer the 1st dose at 6 weeks of age, the 2nd dose at 10 weeks of age, and the 3rd dose at 14 weeks of age. If a child has not received the 1st dose by the age of his initial year, start vaccination as soon as possible and consult your child’s doctor for the schedule.

Combe Five Suspension for Injection can cause some minor and temporary side effects such as fever, irritation, loss of appetite, injection site reaction (pain, swelling, redness), and skin rash. However, these episodes do not last very long and subside on their own. If worrisome, do seek the doctor's help.

Talk to your child’s doctor before vaccination if your child has a history of liver problems, kidney problems, blood disorders, birth defects, heart problems, lung problems, severe pain or swelling of the limbs, or Guillain-Barré syndrome. Also, let your doctor know if your child has or had any severe allergic reactions to any medicine. You should also consult your doctor if your child has ever been in a coma or has had brain or nervous system problems like seizures before scheduling a vaccination appointment. This information is important for the doctor to prepare a corresponding vaccination schedule.

Benefits of Combe Five Suspension for Injection

In Prevention of Diphtheria

Diphtheria is a bacterial infection that causes pain and swelling in the throat. This may even cause difficulty in breathing. It might also damage the heart, kidneys, and nerves. Combe Five Suspension for Injection protects against diphtheria. It is advisable to consult your doctor for complete information regarding vaccination schedules. After vaccination, most children develop antibodies sufficient enough to protect against diphtheria.

In Prevention of Tetanus

Tetanus, commonly called lockjaw, is a serious bacterial infection that affects the nervous system and causes muscles to become stiff and tighten. Combe Five Suspension for Injection helps prevent tetanus infection. It helps the immune system to produce antibodies to fight against tetanus infection. Vaccination is the best way to protect your child against this life-threatening disease.

In Prevention of Pertussis

Pertussis (often called whooping cough) is an infection of the airways that can occur at any age but mostly affects infants and young children. The infection causes uncontrollable coughing, making breathing difficult. Combe Five Suspension for Injection offers the best protection against Pertussis. It is advisable to consult your doctor to gather complete information regarding vaccination schedules.

In Prevention of Prevention of Hepatitis B infection

Hepatitis B is a liver disease caused by contracting the hepatitis B virus. When Combe Five Suspension for Injection is given to children, the immune system is stimulated thereby producing antibodies against this virus. These antibodies help provide protection against infection caused by the hepatitis B virus.

In Prevention of Haemophilus influenzae Type b disease

Haemophilus Influenzae type b can cause serious illness, especially in children. These may include meningitis (infection of brain meninges), pneumonia, etc. It is spread mainly through contact with infected droplets (coughing or sneezing) or secretions from an infected person's nose and throat. Combe Five Suspension for Injection provides long-term protection against this disease. It helps the immune system to produce antibodies to fight against the disease.

Side effects of Combe Five Suspension for Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Combe Five

  • Fever
  • Irritation
  • Loss of appetite
  • Injection site reactions (pain, swelling, redness)
  • Skin rash

How to use Combe Five Suspension for Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Combe Five Suspension for Injection works

Combe Five Suspension for Injection is a combination of five vaccines. It helps develop immunity by initiating a mild infection in the body. This type of infection does not cause illness but stimulates the body's immune system to produce antibodies (proteins) to protect against any future infections.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Combe Five Suspension for Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Combe Five Suspension for Injection during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Combe Five Suspension for Injection during breastfeeding is not available. Please consult your doctor.
Not intended for use in adults.
Driving
CONSULT YOUR DOCTOR
It is not known whether Combe Five Suspension for Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Combe Five Suspension for Injection is safe to use in patients with kidney disease. No dose adjustment of Combe Five Suspension for Injection is recommended.
Liver
SAFE IF PRESCRIBED
Combe Five Suspension for Injection is safe to use in patients with liver disease. No dose adjustment of Combe Five Suspension for Injection is recommended.

What if you forget to take Combe Five Suspension for Injection?

Do not panic. If you miss a schedule of Combe Five Suspension for Injection, do consult your child’s doctor and get your child vaccinated as soon as possible.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Maintain a log of your child’s vaccination history. Be sure to ask for a personal record card or a printed copy of your child’s vaccinations. Whenever your child receives a vaccine, make sure your copy gets updated.
  • Vaccines can ensure the best protection when given at the right time. The Government of India has designed a National Immunization Schedule which suggests a timeline for vaccines to be given to infants, young children, and adolescents when they are vulnerable to specific vaccine-preventable diseases.
  • The duration of immunity varies with different diseases and different vaccines. Usually, the protection provided by vaccines decreases gradually over time. Neither natural infection nor vaccination may be able to provide lifelong immunity. Therefore, booster doses are sometimes recommended for certain vaccines, at specific ages.

Fact Box

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Patient concerns

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Which types of vaccinations are mandatory for a child Which vaccinations are important for a child.
Dr. Gopal Samdani
Paediatrics
Diphtheria/Tetanus/Pertussis (DTaP) -- Five-Dose Series. 2-4 months: Hepatitis A (Hep A) -- Two-Dose Series. 12-23 months: Hepatitis B (Hep B) Birth: H. influenzae type b (Hib) -- Three-Dose Series. 2-4 months: Influenza. Measles/Mumps/Rubella (MMR) -- Two-Dose Series. Pneumococcal (PCV) Chickenpox (Varicella)
Can a complete remedy medicine be expected for hepatitis b disease in coming years? This is my result is there any chance of me naturally become hepatitis b negative?
Dr. Sfurti Mann
Diabetology
IgM anti HBcAg, LFT ultrasound abdomen n HBV viral load(quantitative) HbeAg required to know whether it is chronic infection or carrier state
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User feedback


FAQs

Why are vaccinations important in children?

Vaccinations protect your child against serious diseases by stimulating the immune system to create antibodies against certain bacteria or viruses.

What is the Universal Immunization Program?

Universal Immunisation Program is a vaccination program followed in India. Under this program, all infants and children are vaccinated to ensure prevention against many serious life-threatening diseases such as Diphtheria, Pertussis, Tetanus, Polio, Measles, severe forms of childhood tuberculosis, Hepatitis B, Haemophilus influenzae type b (Hib), and Diarrhea.

When can I call my child fully vaccinated?

A fully immunized child has received all vaccines recommended in the National Immunization Schedule in required doses, at the appropriate age.

What is the duration of immunity provided by immunization?

The duration of immunity varies with different diseases and different vaccines. Lifelong immunity is not always provided by either natural infection or vaccination. The protection provided by vaccines decreases gradually over time. Therefore, booster doses are sometimes recommended for certain vaccines to protect specific age groups.

Is a booster dose recommended for Combe Five Suspension for Injection under the Universal Immunization Programme?

Currently a booster dose is not recommended for Combe Five Suspension for Injection under Universal Immunization Programme. This is because the Hib vaccine protects for at least 15 years.<br>However, the boosters for Diphtheria, Pertussis, and tetanus (DPT) are recommended at 16-24 months and 5-6 years of age.

Can I get my child vaccinated if he or she has a cold or fever, or is on antibiotics?

Yes. Your child can still get vaccinated if he or she has a mild illness, a low-grade fever, or is taking antibiotics. Vaccination should be delayed only if your child's immunity is severely low or your child is suffering from any systemic illness that leads to low immunity. It would be best to talk with your child’s doctor if you have questions.

What if I miss an appointment? Does my baby have to start the vaccines all over again?

No. If your baby misses some doses, it is not necessary to start over. Your child’s doctor may suggest continuing the schedule where your child left off.

How do I keep a track of my child’s vaccination?

Usually, a record of all the vaccination which a child takes is maintained in many medical practices. So, remember to ask for a personal record card or a printed copy of your child’s vaccinations. However, it is still advised to keep records of your own at home. Always carry your copy of the record to all medical appointments. Whenever your child receives a vaccine, make sure your copy gets updated. Your child will benefit by having an accurate vaccination record throughout his or her life.

What is herd immunity? How do vaccines help achieve it?

Herd immunity is a form of indirect protection from an infectious disease. It occurs when a sufficient percentage of a population becomes immune to an infection, either through vaccination or due to self-developed immunity against previous infections. Herd immunity helps reduce the likelihood of infection for individuals who lack immunity.

What is the reason that some children suffer from vaccine-preventable disease even though they have been vaccinated against that disease?

Vaccines have been used for decades and have proven to be effective. Like any other medicine, vaccines too cannot provide 100% results. The immunity produced by vaccines may vary from child to child. There may be children who may not be able to develop sufficient protective immunity against a disease-causing pathogen due to malnutrition, repeated episodes of diarrhea, or individual-specific immune response to a vaccine. These reasons may cause some children to suffer from vaccine-preventable diseases despite receiving the vaccination against them. However, in such cases, the disease is of less severity than in those who have never been vaccinated.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Diphtheria, Tetanus, Pertussis (Whole Cell), Hepatitis B (rDNA) and Haemophilus Type b Conjugate Vaccine (Adsorbed) [Summary of Product Characteristics]. Solan, Himachal Pradesh: Panacea Biotec Ltd.; 2009. [Accessed 11 Aug. 2021] (online) Available from:External Link
  2. Diphtheria, Tetanus, Pertussis (Whole Cell), Hepatitis B (rDNA) and Haemophilus Type b Conjugate Vaccine (Adsorbed) I.P. Genome Valley, Hyderabad: Bharat Biotech. [Accessed 11 Aug. 2021] (online) Available from:External Link
  3. Ministry of Health $ Family Welfare, Government of India. Frequently Asked Questions on Immunization. 2017. [Accessed 11 Aug. 2021] (online) Available from:External Link
  4. MSF Medical Guidelines. Diphtheria, Tetanus, Pertussis, Hepatitis B, Hib Vaccine. [Accessed 11 Aug. 2021] (online) Available from:External Link
  5. Caring for Kids. 5-in-1 or 6-in-1 vaccine. [Last updated May 2021]. [Accessed 11 Aug. 2021] (online) Available from:External Link

Marketer details

Name: Biological E Ltd
Address: Biological E. Limited, Road No. 35,Jubilee Hills, Hyderabad, Telangana -500033
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Combe Five Suspension for Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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0.5 ml in 1 vial
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