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Dargen 25 Injection

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Product introduction

Dargen 25 Injection is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells.

Dargen 25 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.

Common side effects include abdominal pain, high blood pressure, rash, injection site pain, breathlessness, cough, and peripheral edema. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).

Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or skin rash.

Before taking Dargen 25 Injection, tell your doctor if you have heart disease, high blood pressure, or have had a seizure or stroke. If you are pregnant or breastfeeding, or plan to become pregnant or breastfeed, consult your doctor to make sure it is safe for you.

Uses of Dargen Injection


How to use Dargen Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dargen Injection works

Dargen 25 Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.

Safety advice

Alcohol
There is no data available. Please consult doctor before consuming the drug.
Pregnancy
There is no data available. Please consult doctor before consuming the drug.
Breast feeding
There is no data available. Please consult doctor before consuming the drug.
Driving
There is no data available. Please consult doctor before consuming the drug.
Kidney
There is no data available. Please consult doctor before consuming the drug.
Liver
There is no data available. Please consult doctor before consuming the drug.

What if you forget to take Dargen Injection?

If you miss a dose of Dargen 25 Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips

  • Dargen 25 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
  • It is given as a single injection under your skin, additionally, it can be given intravenously.
  • Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells, in your blood.
  • Stop taking Dargen 25 Injection and inform your doctor if you develop shortness of breath or skin rash.

Fact Box

Chemical Class
Amino Acids, Peptides Analogues
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Erythropoiesis-stimulating agent (ESA)

Patient concerns

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Dr. Sir, I have facing depression again after 2 year , and I don't know what was it's triggered point. Kindly tell me what should i do in this situation, I am bachelor. Is Zyven is good for this situation as it was earlier suggest by psychiatrist.
Dr. Jyoti Kapoor Madan
Psychiatry
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
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Dr. Megha Gupta
Obstetrics and Gynaecology
Such problems are common after getting ovaries removed. Do not worry, these problems will eventually fade with time. However if it causes discomfort and restlessness, you should see your gynaecologist for hormonal replacement therapy
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User feedback


FAQs

How long does it take for Dargen 25 Injection to start working?

You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Dargen 25 Injection. If you have any other concerns, consult your doctor.

Is Dargen 25 Injection safe to use?

Dargen 25 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Dargen 25 Injection therapy. Follow all the directions strictly.

Other than PRCA, can there be other reasons for not responding to Dargen 25 Injection?

You may not respond to Dargen 25 Injection if you have deficiencies of iron, folic acid or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation and bone marrow fibrosis. Therefore, consult our doctor regarding the same.

Can Dargen 25 Injection be used in children?

Yes, Dargen 25 Injection is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Dargen 25 Injection and side effects seen in children are similar to adults. However, consult your doctor if you are not sure.

Can Dargen 25 Injection affect blood pressure?

Yes, Dargen 25 Injection can affect blood pressure. During initial therapy with Dargen 25 Injection, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Dargen 25 Injection if the blood pressure remains uncontrolled.

Who should not take Dargen 25 Injection?

Individuals who have cancer but have not been prescribed Dargen 25 Injection by the doctor should not take it. Additionally, patients with uncontrolled hypertension (high blood pressure), patients with a history of anemia called pure red cell aplasia (PRCA) that starts after treatment with Dargen 25 Injection or other erythropoietin medicines, and patients with a history of serious allergic reaction to this medicine should not take this medicine.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 358-59.
  3. Darbepoetin alfa. Milton Road, Cambridge: Amgen Ltd.; 2001 [revised Sep. 2017]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  4. Darbepoetin alfa. Thousand Oaks, CA: Amgen Inc.; 2001. [Accessed 07 Apr. 2019] (online) Available from:External Link
  5. CiplaMed. Darbepoetin Alfa [Product Information]. [Last Reviewed: June 2019]. [Accessed 17 Jun. 2023] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Darbepoetin. [Accessed 17 Jun. 2023] (online) Available from:External Link
  7. Darbepoetin alfa [Prescribing Information]. Thousand Oaks, California: Amgen Inc.; 2019. [Accessed 17 Jun. 2023] (online) Available from:External Link
  8. Aranesp Injection (Darbepoetin alfa) [Product Information]. [Accessed 17 Jun. 2023] (online) Available from:External Link

Marketer details

Name: Lupin Ltd
Address: Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India .
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Dargen 25 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

1294.551523Get 15% OFF
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0.42 ml in 1 prefilled syringe
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