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MDS (Oral Pathology & Microbiology), BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Desifer 400 Tablet


Product introduction

Desifer 400 Tablet is a medicine used in the treatment of chronic iron overload caused by frequent blood transfusion. It helps remove the excess iron from the body and reduce the risk of it causing organ damage.

Repeated blood transfusions in some patients can cause a build-up of excess iron. Desifer 400 Tablet is used to remove the excess iron from the body

Uses of Desifer Tablet

Benefits of Desifer Tablet

In Treatment of Iron overload

Iron overload, as the name suggests, means excess of iron in the human body. Too much iron can cause organ damage, which can lead to conditions such as cancer, irregular heartbeat and cirrhosis of the liver. Symptoms are related to conditions that arise from iron overload such as high blood sugar levels (diabetes), darkening of the skin, abnormal heart rhythm or arthritis. By using Desifer 400 Tablet, this excess of iron can be decreased to safe levels by removing it from the body through stools. This helps to reduce the risk of organ damage and prevents further complications. Take Desifer 400 Tablet as prescribed by the doctor to get the maximum benefit.

Side effects of Desifer Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Desifer

  • Nausea
  • Headache
  • Vomiting
  • Rash
  • Abdominal pain
  • Constipation
  • Itching
  • Increased liver enzymes
  • Abdominal distension
  • Diarrhea

How to use Desifer Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Desifer 400 Tablet is to be taken empty stomach.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Desifer 400 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Desifer 400 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Desifer 400 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Desifer 400 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
UNSAFE
Desifer 400 Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Liver
CAUTION
Desifer 400 Tablet should be used with caution in patients with liver disease. Dose adjustment of Desifer 400 Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Desifer 400 Tablet in these patients.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Desifer 400 Tablet
₹90.0/Tablet
Thalep 400mg Tablet
Intas Pharmaceuticals Ltd
₹32.5/tablet
64% cheaper

Quick tips

  • Desifer 400 Tablet is used to reduce excess iron from the body.
  • Inform your doctor if you also have upper stomach pain, clay-colored stools, or jaundice (yellowing of your skin or the whites of your eyes).
  • Take an adequate amount of water while taking Desifer 400 Tablet. 
  • Desifer 400 Tablet may cause dizziness. It is advisable not to drive or operate any machinery until you feel normal again.
  • If you are taking any antacid, take them 2 hours before or after Desifer 400 Tablet.
  • Inform your doctor if you have any liver or kidney disease.
  • Inform your doctor if you are pregnant or breastfeeding.

Fact Box

Chemical Class
Triazole & benzoate derivative
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Iron chelating agents

Patient concerns

arrow
Hello doctor I have thallassemia major since birth and due to iron overload of repetitive blood transfusion i have diagnosed with diabetes 3 yr ago -at the time of diabetes diagnosis my sugar level is 650 mg/dl. Now according to my case what could be the state of my diabetes type 1 or type 2 ?
Dr. Amit Modi
Paediatrics
Hello, Diabetes in thalassaemia is thought to be caused mainly by iron overload, from repeated blood transfusions, damaging the pancreas. Insulin secretion may be reduced, possibly because iron is directly toxic to the insulin producing pancreatic ?-cells. So it is type 1 DM .
Hello doctor i have thallasemia major since birth and due to iron overload of repetitive blood transfusions from this disease i was diagnosed with diabetes 2 yrs. ago Now my query is can i control my sugar by controlling iron/ferritin?
Dr. Ashwin Porwal
Internal Medicine
No you have to take insulin or Oral hypoglycemic agents for it
arrow

User feedback


FAQs

What is Desifer 400 Tablet used for?

Desifer 400 Tablet is used for removing excess iron from the body due to repeated blood transfusions in patients with beta thalassemia major (a blood disorder)

How does Desifer 400 Tablet work?

Desifer 400 Tablet works by binding to excess iron in the blood and removing it from the body through stool.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Byrns MC, Penning TM. Environmental Toxicology: Carcinogens and Heavy Metals. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1875-76.
  2. Kosnett MJ. Heavy Metal Intoxication & Chelators. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1010.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 365.
  4. Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 [revised 23 Jul. 2018]. [Accessed 6 Apr. 2019] (online) Available from:External Link
  5. Medscaape. Deferasirox. [Accessed 6 Apr. 2019] (online) Available from:External Link
  6. Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 [revised 23 Jul. 2018]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  7. Drugs.com. Deferasirox Pregnancy and Breastfeeding Warnings. [Accessed 6 Apr. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 6 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Desifer 400 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

459540Get 15% OFF
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Inclusive of all taxes
Get this discount by applying coupon 1MGALL on the cart. Max. coupon discount is ₹380. T&C apply.
6.0 tablets in 1 strip
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