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Dothee 25 Tablet
Prescription Required
Product introduction
Dothee 25 Tablet is a tricyclic antidepressant. It is mostly used to treat depression that is unresponsive to alternative treatment. It is also used in the management of anxiety disorder.
Dothee 25 Tablet is used to treat various features of depression
Dothee 25 Tablet is used to treat various features of depression
Uses of Dothee Tablet
- Treatment of Anxiety disorder
- Treatment of $name is thought to work by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieves anxiety and tension, helps you sleep better, and increases your energy level. It is used to treat depression that is unresponsive to other medicines. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly. Depression
Benefits of Dothee Tablet
In Treatment of Anxiety disorder
Dothee 25 Tablet is thought to work by stopping your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, irritability, and sleep problems that often come with Generalised Anxiety Disorder. It will, therefore, help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.
Side effects of Dothee Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dothee
- Dryness in mouth
- Increased heart rate
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Weight gain
- Difficulty in urination
- Constipation
- Blurred vision
How to use Dothee Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dothee 25 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Safety advice
Alcohol
UNSAFE
Dothee 25 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Dothee 25 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Dothee 25 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Dothee 25 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Dothee 25 Tablet in patients with kidney disease. Please consult your doctor.
However, some studies suggest a cautious use of this medicine in patients with kidney disease.
However, some studies suggest a cautious use of this medicine in patients with kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Dothee 25 Tablet in patients with liver disease. Please consult your doctor.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- It may take 4 to 6 weeks for Dothee 25 Tablet to start working. Keep taking it as prescribed.
- It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
- Avoid consuming alcohol when taking Dothee 25 Tablet as it may cause excessive sleepiness.
- Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Fact Box
Chemical Class
Dibenzoxepin Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic antidepressants
Patient concerns
FAQs
What is Dothee 25 Tablet used for?
Dothee 25 Tablet is a medicine used to treat anxiety disorder and depression that is unresponsive to other alternative medicines. It is also used to relieve nerve pain and fibromyalgia. Dothee 25 Tablet should be taken only if prescribed by a doctor, exactly as directed.
Is Dothee 25 Tablet a muscle relaxant?
No. Dothee 25 Tablet is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.
What is the difference between Dothee 25 Tablet and amitriptyline?
Dothee 25 Tablet is chemically related to Amitriptyline and both are tricyclic antidepressant (TCA) medicine. There is overlap in pharmacological property of this medicine.
Is Dothee 25 Tablet the same as doxepin?
Dothee 25 Tablet and doxepin are different medicines but belong to the similar chemical class. Doxepin, at low doses, can improve sleep in patients with insomnia. It is also available in the topical form for use in various neuro-dermatitis syndrome, especially itching.
How to stop Dothee 25 Tablet?
If your doctor asks you to stop Dothee 25 Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spell.
Is Dothee 25 Tablet fatal?
Yes. Dothee 25 Tablet can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.
Can I take Dothee 25 Tablet with diazepam?
It is better to avoid this combination. Diazepam is a sedative drug and Dothee 25 Tablet may cause sedation as a side effect too. Taking both of them together can increase the drowsiness or sleepiness. Inform your doctor if you are taking diazepam.
Can Dothee 25 Tablet be used in the treatment of trigeminal neuralgia?
No. Dothee 25 Tablet is not approved for the treatment of trigeminal neuralgia. Trigeminal neuralgia is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.
Can Dothee 25 Tablet be used in the treatment of burning mouth syndrome?
No. Dothee 25 Tablet is not approved for the treatment of burning mouth syndrome. Burning mouth syndrome is a painful condition of mouth that is burning, scalding, tingling or feeling of numbness that may occur every day for months or longer.
Can I take Dothee 25 Tablet for depression?
Yes. Dothee 25 Tablet is indicated for the treatment of depression. It has a potential advantage in the patient with depression if associated with insomnia and anxiety. It is generally not considered a first-line option for depression because of side effect profile but very useful for severe or treatment-resistant depression.
Can Dothee 25 Tablet used to treat IBS (Irritable Bowel Syndrome)?
No. Dothee 25 Tablet is not approved for the treatment of Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort associated with altered bowel habits.
Can Dothee 25 Tablet be used to treat insomnia with depression?
Yes. Dothee 25 Tablet may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.
Can I use Dothee 25 Tablet for fibromyalgia?
Yes. Dothee 25 Tablet is not approved for the treatment of fibromyalgia. Fibromyalgia is a pain syndrome with tenderness but no structural pathology in muscles, ligamanets or joints.
Can I use Dothee 25 Tablet for nerve pain?
Yes. Dothee 25 Tablet is indicated for the treatment of nerve pain/neuropathic pain. Chronic pain/Neuropathic pain is described as pain that arises from damage to, or dysfunction of, any part of peripheral or central nervous system. It is associated with the disease which can affect nerves like diabetes mellitus or herpes infections.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Dothiepin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 205-10.
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
- PubChem. Dothiepin. [Accessed 22 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
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Address: first floor, heera plaza, sec-8, vikas nagar, lucknow, uttar pradesh 226022
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