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Dothibon 50 Tablet

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Product introduction

Dothibon 50 Tablet is a tricyclic antidepressant. It is mostly used to treat depression that is unresponsive to alternative treatment. It is also used in the management of anxiety disorder.

Dothibon 50 Tablet is used to treat various features of depression

Benefits of Dothibon Tablet

In Treatment of Anxiety disorder

Dothibon 50 Tablet is thought to work by stopping your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness, tiredness, difficulty concentrating, irritability, and sleep problems that often come with Generalised Anxiety Disorder. It will, therefore, help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.

Side effects of Dothibon Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dothibon

  • Dryness in mouth
  • Increased heart rate
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Weight gain
  • Difficulty in urination
  • Constipation
  • Blurred vision

How to use Dothibon Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dothibon 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol
UNSAFE
Dothibon 50 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Dothibon 50 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Dothibon 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Dothibon 50 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Dothibon 50 Tablet in patients with kidney disease. Please consult your doctor.
However, some studies suggest a cautious use of this medicine in patients with kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Dothibon 50 Tablet in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Dothibon 50 Tablet
₹9.6/Tablet
Dothip 50 Tablet
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Dotin 50mg Tablet
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Dozep 50mg Tablet
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DO RE ME 50mg Tablet
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Quick tips

  • It may take 4 to 6 weeks for Dothibon 50 Tablet to start working. Keep taking it as prescribed.
  • It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Dothibon 50 Tablet as it may cause excessive sleepiness.
  • Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Fact Box

Chemical Class
Dibenzoxepin Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic antidepressants

Patient concerns

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Mental Depression , Anxiety disorder
Dr. Jyoti Kapoor Madan
Psychiatry
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
Mixed anxiety depressive disorder
Dr. Jyoti Kapoor Madan
Psychiatry
Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.
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FAQs

What is Dothibon 50 Tablet used for?

Dothibon 50 Tablet is a medicine used to treat anxiety disorder and depression that is unresponsive to other alternative medicines. It is also used to relieve nerve pain and fibromyalgia. Dothibon 50 Tablet should be taken only if prescribed by a doctor, exactly as directed.

Is Dothibon 50 Tablet a muscle relaxant?

No. Dothibon 50 Tablet is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.

What is the difference between Dothibon 50 Tablet and amitriptyline?

Dothibon 50 Tablet is chemically related to Amitriptyline and both are tricyclic antidepressant (TCA) medicine. There is overlap in pharmacological property of this medicine.

Is Dothibon 50 Tablet the same as doxepin?

Dothibon 50 Tablet and doxepin are different medicines but belong to the similar chemical class. Doxepin, at low doses, can improve sleep in patients with insomnia. It is also available in the topical form for use in various neuro-dermatitis syndrome, especially itching.

How to stop Dothibon 50 Tablet?

If your doctor asks you to stop Dothibon 50 Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spell.

Is Dothibon 50 Tablet fatal?

Yes. Dothibon 50 Tablet can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.

Can I take Dothibon 50 Tablet with diazepam?

It is better to avoid this combination. Diazepam is a sedative drug and Dothibon 50 Tablet may cause sedation as a side effect too. Taking both of them together can increase the drowsiness or sleepiness. Inform your doctor if you are taking diazepam.

Can Dothibon 50 Tablet be used in the treatment of trigeminal neuralgia?

No. Dothibon 50 Tablet is not approved for the treatment of trigeminal neuralgia. Trigeminal neuralgia is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.

Can Dothibon 50 Tablet be used in the treatment of burning mouth syndrome?

No. Dothibon 50 Tablet is not approved for the treatment of burning mouth syndrome. Burning mouth syndrome is a painful condition of mouth that is burning, scalding, tingling or feeling of numbness that may occur every day for months or longer.

Can I take Dothibon 50 Tablet for depression?

Yes. Dothibon 50 Tablet is indicated for the treatment of depression. It has a potential advantage in the patient with depression if associated with insomnia and anxiety. It is generally not considered a first-line option for depression because of side effect profile but very useful for severe or treatment-resistant depression.

Can Dothibon 50 Tablet used to treat IBS (Irritable Bowel Syndrome)?

No. Dothibon 50 Tablet is not approved for the treatment of Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort associated with altered bowel habits.

Can Dothibon 50 Tablet be used to treat insomnia with depression?

Yes. Dothibon 50 Tablet may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.

Can I use Dothibon 50 Tablet for fibromyalgia?

Yes. Dothibon 50 Tablet is not approved for the treatment of fibromyalgia. Fibromyalgia is a pain syndrome with tenderness but no structural pathology in muscles, ligamanets or joints.

Can I use Dothibon 50 Tablet for nerve pain?

Yes. Dothibon 50 Tablet is indicated for the treatment of nerve pain/neuropathic pain. Chronic pain/Neuropathic pain is described as pain that arises from damage to, or dysfunction of, any part of peripheral or central nervous system. It is associated with the disease which can affect nerves like diabetes mellitus or herpes infections.

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References

  1. Stahl SM, editor. Dothiepin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 205-10.
  2. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:External Link
  3. PubChem. Dothiepin. [Accessed 22 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Boeing Pharma Pvt Ltd
Address: I-1,302 Global City ,Virar(W), Maharashtra,401303
Country of origin: India

MRP
96
Inclusive of all taxes
10.0 tablets in 1 strip
SOLD OUT
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