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MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Epofer 4000IU Injection


Product introduction

Epofer 4000IU Injection is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidney disease. It is also used to treat anemia caused by cancer chemotherapy and by taking medicines to treat HIV.

Epofer 4000IU Injection is used to treat anemia (deficiency of red blood cells in blood)

Benefits of Epofer Injection

In Treatment of Anemia due to chronic kidney disease

Epofer 4000IU Injection is a man-made protein that helps your bone marrow to produce more red blood cells. It is used to treat anemia which is caused by kidney disease in adults and children who are on dialysis. Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. This medicine helps reduce weakness and tiredness that you may be experiencing due to anemia. The injection is usually given by a doctor after a dialysis treatment.

In Treatment of Anemia due to cancer chemotherapy

Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. Epofer 4000IU Injection is a man-made protein that works by stimulating the bone marrow (soft tissue inside the bones) to produce more red blood cells. The natural human form of this protein may be reduced when you are having chemotherapy to treat some types of cancer. An injection of the medicine can reduce the need to have a blood transfusion. You may also be given iron supplements to make the treatment more effective.

Side effects of Epofer Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Epofer

  • High blood pressure
  • Nausea
  • Vomiting
  • Fever
  • Rash
  • Joint pain
  • Headache
  • Insomnia (difficulty in sleeping)
  • Chills
  • Cough
  • Bone pain
  • Muscle spasm
  • Dizziness
  • Vascular occlusion
  • Injection site irritation
  • Stomatitis (Inflammation of the mouth)
  • Weight loss
  • Decreased white blood cell count (lymphocytes)
  • Increased glucose level in blood
  • Blood clot in the blood vessels

How to use Epofer Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Epofer 4000IU Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Epofer 4000IU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Epofer 4000IU Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Epofer 4000IU Injection may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Epofer 4000IU Injection is safe to use in patients with kidney disease. No dose adjustment of Epofer 4000IU Injection is recommended.
Regular monitoring of kidney function tests is advised while the patient is taking this medicine.
Liver
CAUTION
Epofer 4000IU Injection should be used with caution in patients with liver disease. Dose adjustment of Epofer 4000IU Injection may be needed. Please consult your doctor.

What if you forget to take Epofer Injection?

If you miss a dose of Epofer 4000IU Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Epofer 4000IU Injection
₹950.0/Injection
Vintor 4000 Injection
Emcure Pharmaceuticals Ltd
₹963.8/injection
1% costlier
Eporise 4000 Injection
Zuventus Healthcare Ltd
₹1194/injection
26% costlier
Anfoe 4000IU Injection
La Renon Healthcare Pvt Ltd
₹1299/injection
37% costlier
Renocel 4000IU Injection
Intas Pharmaceuticals Ltd
₹1480/injection
56% costlier
Repoitin 4000 Injection
Serum Institute Of India Ltd
₹1197.89/injection
26% costlier

Quick tips

  • Epofer 4000IU Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
  • It is given as a single injection under your skin.
  • Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as  severe headache, problems with your eyesight, nausea, vomiting or fits (seizures).
  • Stop taking Epofer 4000IU Injection and inform your doctor if you develop shortness of breath or skin rash.

Fact Box

Chemical Class
Amino Acids, Peptides Analogues
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Erythropoiesis-stimulating agent (ESA)

Patient concerns

arrow
Blood Hb is found 5.9 so wat is it
Dr. Ila Jain Khandelwal
Pathology
Dear PATIENT from 1mg. The hemoglobin is very low, which can be due to anemia. I suggest you should consult a Hematologist /Physician for this.
how to resolve the problem of anemia?
Dr. Rekha Pohani
Dietetics/Nutrition
Intake of dates and jaggery will help
arrow

User feedback


FAQs

How should Epofer 4000IU Injection be stored?

In the hospital, pre-filled syringes are stored unopened in a refrigerator between 2 and 8 ℃. If you are using this medicine at home, it is important that the pre-filled syringe is stored in your refrigerator. Do not store it in the freezer. Allow the pre-filled syringe to reach room temperature prior to using it. This usually takes between 15 and 30 minutes. Epofer 4000IU Injection pre-filled syringes that are being used or about to be used can be kept at room temperature (not above 25°C) for a maximum single period of 7 days. Keep these pre-filled syringes away from children and protected from light.

What to do if you use too much Epofer 4000IU Injection?

Tell the doctor or nurse immediately if you think too much Epofer 4000IU Injection has been injected.

When should Epofer 4000IU Injection not be used?

Epofer 4000IU Injection should not be used if the solution is clouded or you can see particles floating in it or if the medicine has expired. Refer to the expiry date on the label. You should also not use the medicine if you know or think that it may have been accidentally frozen or if there has been a refrigerator failure.

Can Epofer 4000IU Injection be used in children?

Yes, Epofer 4000IU Injection is used to treat anemia caused due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Epofer 4000IU Injection and side effects seen in children are similar to adults.

Can Epofer 4000IU Injection affect blood pressure?

Yes, Epofer 4000IU Injection can affect blood pressure. During initial therapy with Epofer 4000IU Injection, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Epofer 4000IU Injection if the blood pressure remains uncontrolled.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. ScienceDirect. Recombinant Human Erythropoietin Alfa/Epoetin Alfa. [Accessed 07 Apr. 2019] (online) Available from:External Link
  2. Recombinant Human Erythropoietin Alfa/Epoetin Alfa. Leiden, Netherlands: Janssen Biologics B.V; [revised Oct. 2018]. [Accessed 07 Apr. 2019] (online) Available from:External Link
  3. Recombinant Human Erythropoietin Alfa/Epoetin Alfa. Amgen Inc; 1989 [revised Dec. 2013]. [Accessed 07 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Emcure Pharmaceuticals Ltd
Address: 255/2, Hinjawadi, Pune - 411057, India
Country of origin: India

DISCONTINUED
We do not facilitate sale of this product at present
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