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Written By
Dr. Sakshi Sharma
BDS
Reviewed By
Dr. Ashish Ranjan
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Introduction of Exact 3 Tablet

Exact 3 Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

Exact 3 Tablet is a combination of rifampicin, isoniazid, and ethambutol.

Uses of Exact 3 Tablet

Benefits of Exact 3 Tablet

In Treatment of Tuberculosis (TB)

Tuberculosis is an infectious disease that mainly affects the lungs but can affect other parts of the body as well. Exact 3 Tablet helps treat tuberculosis by stopping the growth of bacteria causing infection. Your symptoms might improve after using Exact 3 Tablet. However, make sure to complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.

Side effects of Exact 3 Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Exact 3

  • Nausea
  • Vomiting
  • Rash
  • Fever
  • Dark colored urine
  • Sweating
  • Increased sputum production
  • Salivation
  • Watery eyes
  • Increased liver enzymes
  • Jaundice
  • Visual impairment
  • Increased uric acid level in blood
  • Gout
  • Peripheral neuropathy (tingling and numbness of feet and hand)

How to use Exact 3 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Exact 3 Tablet is to be taken empty stomach.
Avoid Exact 3 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking Exact 3 Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Exact 3 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Exact 3 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Exact 3 Tablet may cause side effects which could affect your ability to drive.
Exact 3 Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Exact 3 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Exact 3 Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Exact 3 Tablet should be used with caution in patients with liver disease. Dose adjustment of Exact 3 Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Exact 3 Tablet
₹9.83/Tablet
Akurit-3 Tablet
Lupin Ltd
₹5.01/tablet
49% cheaper
Mycurit 3 Tablet
Cadila Pharmaceuticals Ltd
₹1.98/tablet
80% cheaper
Monitor 3 150 mg/75 mg/275 mg Tablet
Shreya Life Sciences Pvt Ltd
₹1.42/tablet
86% cheaper
Rimthree Fdc 150 mg/75 mg/275 mg Tablet
Novartis India Ltd
₹2.08/tablet
79% cheaper

Quick tips

Exact 3 Tablet

  • It is best to take the medicine on an empty stomach one hour before or two hours after meals.
  • Finish the prescribed course of medicine, even if you start to feel better. Stopping it early may make the infection harder to treat.
  • It can make birth control pills less effective so ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm, spermicide).
  • It can cause temporary discoloration of your teeth, sweat, urine, saliva, and tears (red, orange, or brown color). This side effect is usually not harmful. 

Fact Box

Habit Forming
No
Therapeutic Class
ANTI INFECTIVES

Patient concerns

Patient concerns

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Can I take Exact 90 instead of Acer 90 tablet
Dr. Nabajit Talukdar
Interventional Cardiology
if same active ingredient yes
MORE
My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
MORE
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FAQs

Exact 3 Tablet

Which is the best time to take Exact 3 Tablet?

Take Exact 3 Tablet exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.

Can the use of Exact 3 Tablet make birth control pills ineffective?

Yes, Exact 3 Tablet can make birth control pills less effective. Ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm, spermicide).

Is tuberculosis a curable disease?

Yes, tuberculosis (TB) is a curable disease and can be cured with 6–9 months of treatment. Drug-resistant forms of TB are also curable, but more difficult to treat. Treatment for drug-resistant TB can last up to 2 years and require medications that can cause serious side effects.

What are the instructions for the storage and disposal of Exact 3 Tablet?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can the use of Exact 3 Tablet cause discoloration of the urine?

Yes, Exact 3 Tablet contains rifampicin which can cause temporary discoloration of your teeth, sweat, urine, saliva, and tears (red, orange, or brown color). This side effect is usually not harmful. However, discoloration of urine can be a sign of liver damage. Call your doctor if you have discoloration of urine with stomach pain, loss of appetite, and jaundice (yellowing of your skin or eyes).

Can I discontinue Exact 3 Tablet if I feel well?

No, do not discontinue Exact 3 Tablet. Take the proper course of the drug that has been prescribed to you even if you begin to feel better. If you stop taking Exact 3 Tablet, your infection may become worse and difficult to treat. It may even result in drug-resistant TB i.e. drugs you were taking may no longer work for Tuberculosis.

Can Exact 3 Tablet cause visual impairment?

Exact 3 Tablet contains Ethambutol, which may cause visual impairment. Inform the doctor immediately if you notice any changes in your eyesight.
Related lab tests
  • Complete Blood Count
  • Erythrocyte Sedimentation Rate
  • Mycobacterium Tuberculosis DNA PCR - Qualitative
  • Peripheral Smear Examination

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    Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

    References

    1. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Hilal-Dandan R, Brunton LL. Goodman and Gilman's Manual of Pharmacology and Therapeutics. 2nd ed. New York, New York: The McGraw-Hill Companies, Inc.; 2014. [Accessed 10 Apr. 2019] (online) Available from:External Link
    2. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 10 Apr. 2019] (online) Available from:External Link
    3. Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 10 Apr. 2019] (online) Available from:External Link

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    Address: Marc Laboratories Limited, Plot No. 112, HP HIDC, Baddi, Solan-173205, Himachal Pradesh, India
    Country of origin: India
    NOT FOR SALE
    We do not facilitate sale of this product at present

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