Glourea 500mg Capsule is used in the treatment of some kinds of cancer and to prevent painful episodes associated with sickle cell anemia. It may be also used to treat some other conditions. It is sometimes used with certain other medicines as part of combination chemotherapy.

Glourea 500mg Capsule is used to treat various types of cancer

Uses of Glourea Capsule

Benefits of Glourea Capsule

In Head and neck cancer

Head and neck cancer includes cancer of the mouth, nose, sinuses or throat. Glourea 500mg Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

In Sickle cell anemia

Sickle cell anemia is a disorder of the red blood cells (RBCs) in which they lose their original round shape and flexibility, turn sickle shape and eventually die out. Glourea 500mg Capsule makes your red blood cells bigger. It helps them stay rounder and more flexible and makes them less likely to turn into a sickle shape. The medicine does this by increasing a special kind of hemoglobin called hemoglobin F. Hemoglobin F is also called fetal hemoglobin because newborn babies have it. This helps to treat this disease and also prevents further complications that may be life-threatening.

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Side effects of Glourea Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Glourea

Hematological disorder
Gastrointestinal disorder
Eating disorder
Azoospermia (absence of sperms)
Decreased appetite
Fever
Oligospermia (low sperm count)
Skin cancer
Bone marrow suppression
Hallucination
Convulsion
Peripheral neuropathy (tingling and numbness of feet and hand)
Pulmonary fibrosis
Pulmonary edema
Pancreatic inflammation
Liver toxicity
Cutaneous vasculitis
Increased uric acid level in blood

How to use Glourea Capsule

Take this medicine in the dose and duration as advised by your doctor. Glourea 500mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Glourea 500mg Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Glourea 500mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Glourea 500mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Glourea 500mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Glourea 500mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Glourea 500mg Capsule may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may be advised while you are taking this medicine.

Liver

CAUTION

Glourea 500mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Glourea 500mg Capsule may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Glourea 500mg Capsule

₹5.9/Capsule

Myelostat 500mg Capsule

Zydus Cadila

₹7.55/capsule

28% costlier

Cytodrox Capsule

Cipla Ltd

₹6.58/capsule

12% costlier

Hydrogem 500mg Capsule

Neon Laboratories Ltd

₹3.2/capsule

46% cheaper

Durea 500mg Capsule

Samarth Life Sciences Pvt Ltd

₹6.71/capsule

14% costlier

Riborea Capsule

Khandelwal Laboratories Pvt Ltd

₹6/capsule

2% costlier

View all substitutes

Quick tips

Take it at the same time every day, either with or without food.
It is advisable to stay hydrated and drink plenty of fluids while taking Glourea 500mg Capsule.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.

Fact Box

Chemical Class

Anti Metabolites, {Urea}

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anticancer-others

Patient concerns

I'm sickle cell patient now strong pain occurs what i can do ,my MRI report uploaded

Dr. Kamal Rijhwani

Physician

There is sickle cell society in NagpurFind on net and consult

the injection said is Haemaz fort Injection of 5 ml, total 4 nos. injection is injected to sickle cell disease patient, if Hb is 7 gram, what will be the effect to patient?

Dr. Pushkar Mani

Physician

we dont treat sickle cell anaemia online, u need to consult hematologist

I want to know the symptoms of cancer as I am a smoker

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.

FAQs

How to get relief from diarrhea while on treatment with Glourea 500mg Capsule?

Food items with soluble fiber can help relieve diarrhea as they help absorb excess fluid from the body. These food items include bananas (ripe), oranges, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid dehydration. You can also have soups and juice frequently to hydrate yourself.

Should I avoid any food and drinks while taking Glourea 500mg Capsule?

You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent you from becoming dehydrated, eat small, simple but nourishing snacks every few hours rather than large meals, and suck on hard candy or popsicles to prevent nausea and vomiting.

How to cope with tiredness and weakness after starting treatment?

Various things can help you to reduce tiredness and cope with it, for example, gentle exercise. Always consult your doctor before doing any kind of exercise.

Can Glourea 500mg Capsule be taken during pregnancy?

This treatment may harm a baby developing in the womb. It is important not to become pregnant or father a child while you are having treatment and for at least 6 months afterward. Talk to your doctor about effective contraception before starting the treatment.

Does Glourea 500mg Capsule cause hair loss?

Yes, while taking this medicine, your hair may become brittle and break. You may also experience patchy hair loss or thinning. These conditions tend to resolve once treatment is stopped. Be gentle when brushing and washing hair to manage hair loss.

I have noticed some changes in my skin after taking Glourea 500mg Capsule? What should I do?

Use a moisturizer to get relief from rashes, and dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen (SPF of more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water baths and wear loose and cotton fabric clothes. Your skin will tend to become better once treatment is stopped.

How to relieve constipation during the treatment?

To relieve constipation, include fiber in your diet (fruits and vegetables), drink 8-10 glasses of fluids a day, and keep active. A stool softener (with a doctor's prescription) once or twice a day may prevent constipation. If you do not have a bowel movement for 2-3 days, consult your doctor.

What precautions should I take to reduce the chances of getting infected during treatment with Glourea 500mg Capsule?

Since Glourea 500mg Capsule lowers the number of white blood cells and platelets in your blood, it puts you at a risk of getting an infection. In order to prevent, avoid people who have infections. Check with your doctor immediately if you think you may be getting an infection, or if you get a fever, or chills.

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Related lab tests

Complete Blood Count

Peripheral Smear Examination

Reticulocyte Count

Sickling Test

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1721-22.
Masters SB. Agents Used in Anemias; Hematopoetic Growth Factors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 578.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 672-75.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Hydroxyurea. [Updated 2020 Jan 20]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Marketer details

Name: Globela Pharma Pvt Ltd

Address: 357, G.I.D.C. Road No.3,Sachin, Surat - 394 230 ,Gujarat, India

Country of origin: India

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