Glyfine M 80mg/500mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Glyfine M 80mg/500mg Tablet is used in the treatment of type 2 diabetes mellitus . It is a combination medicine that can control blood sugar better than single medication. It should be used along with a proper diet and regular exercise for best results. Hypoglycemia (low blood sugar level) may occur as a side effect and it should be taken with food to avoid upset stomach.

Uses of Glyfine M Tablet

Treatment of Type 2 diabetes mellitus

Benefits of Glyfine M Tablet

In Treatment of Type 2 diabetes mellitus

Glyfine M 80mg/500mg Tablet is a medicine that helps to control high blood glucose (sugar) levels. It helps get rid of extra glucose from your body through urine. It also improves the body’s response to the hormone insulin, which is responsible for regulating blood glucose (sugar) levels in our body. The insulin helps to lower your blood glucose levels and prevents them from rising after taking meals.
You should keep taking it for as long as it is prescribed. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Glyfine M Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Glyfine M

Hypoglycemia (low blood glucose level)
Headache
Nausea
Dizziness
Diarrhea
Flatulence

How to use Glyfine M Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glyfine M 80mg/500mg Tablet is to be taken with food.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Glyfine M 80mg/500mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Glyfine M 80mg/500mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Glyfine M 80mg/500mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Glyfine M 80mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glyfine M 80mg/500mg Tablet may be needed. Please consult your doctor.
Use of Glyfine M 80mg/500mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Liver

CAUTION

Glyfine M 80mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Glyfine M 80mg/500mg Tablet may be needed. Please consult your doctor.
Glyfine M 80mg/500mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

What if you forget to take Glyfine M Tablet?

If you miss a dose of Glyfine M 80mg/500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Glyfine M 80mg/500mg Tablet

₹2.5/Tablet

Glizid-M Tablet

Mankind Pharma Ltd

₹5.1/tablet

104% costlier

Glykind-M Tablet

Mankind Pharma Ltd

₹3.75/tablet

50% costlier

Dianorm-M Tablet

Micro Labs Ltd

₹6.33/tablet

153% costlier

Diabend-M Tablet

Bal Pharma Ltd

₹4.33/tablet

73% costlier

Glycigon-M Tablet

Aristo Pharmaceuticals Pvt Ltd

₹3.94/tablet

58% costlier

View all substitutes

Quick tips

Glyfine M Tablet

Monitor your blood sugar level regularly while you are taking this medicine.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glyfine M 80mg/500mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Fact Box

Habit Forming

Therapeutic Class

ANTI DIABETIC

Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 required only ayurvedic medicine

Dr. Sanjay Bhatt

Physician

Go for allopathic medicine

Any latest discoveris for type 1 mellitus Diabetes?

Dr. Sanjay Bhatt

Physician

Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).

How to manage diabetes mellitus

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND LOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you souls not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

FAQs

Glyfine M Tablet

What is Glyfine M 80mg/500mg Tablet?

Glyfine M 80mg/500mg Tablet is a combination of two medicines: Gliclazide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Gliclazide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.

What are the possible side effects of Glyfine M 80mg/500mg Tablet?

The use of Glyfine M 80mg/500mg Tablet is associated with common side effects. These side effects may include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Can the use of Glyfine M 80mg/500mg Tablet cause hypoglycemia?

Yes, the use of Glyfine M 80mg/500mg Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.

Can the use of Glyfine M 80mg/500mg Tablet cause lactic acidosis?

Yes, the use of Glyfine M 80mg/500mg Tablet can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin. It is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Glyfine M 80mg/500mg Tablet and immediately consult your doctor.

Can the use of Glyfine M 80mg/500mg Tablet lead to Vitamin B12 deficiency?

Yes, the use of Glyfine M 80mg/500mg Tablet can cause vitamin B12 deficiency on long-term use. The deficiency occurs as the medicine interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Are there any specific conditions in which Glyfine M 80mg/500mg Tablet should not to be taken?

The use of Glyfine M 80mg/500mg Tablet should be avoided in patients with known allergy to any of the component or excipients of this medicine. It is also avoided in patients with moderate to severe kidney disease or with underlying metabolic acidosis including diabetic ketoacidosis.

Is it safe to take alcohol while I am also taking Glyfine M 80mg/500mg Tablet?

No, it is not safe to take alcohol along with Glyfine M 80mg/500mg Tablet. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

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Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

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References

Gottwald-Hostalek U, Schlachter J, Geloneze B. Combination Therapy with Metformin plus Gliclazide in Patients with Type 2 Diabetes. J Dia Res Ther. 2016;2(3). [Accessed 08 Apr. 2019] (online) Available from:
Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:
Gliclazide+Metformin [Product Monograph]. Solan, Himachal Pradesh: Panacea Biotec Limited; 2019. [Accessed 23 Sept. 2021] (online) Available from:
American Diabetes Association. 9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2020. Diabetes Care. 2020;43(Suppl 1): S98-S110. [Accessed 23 Sept. 2021] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 13 Mar. 2019] (online) Available from:

Marketer details

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Country of origin: India

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