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MD (Pharmacology), MBBS
Last updated
22 Sep 2021 | 08:59 AM (IST)

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Grandem MD Tablet

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Product introduction

Grandem MD Tablet is an antiemetic medicine commonly used to control nausea and vomiting caused due to any surgery, cancer drug therapy, or radiotherapy.

Grandem MD Tablet will not relieve other side effects associated with cancer treatments. It also has little effect on vomiting caused by motion sickness. You should take this medicine in the dose and duration advised by your doctor. But, it is better to take this medicine at a fixed time. Remember, you should not stop taking this medicine suddenly without talking to your doctor. In case you vomit within one hour of taking a dose, then take another dose and avoid heavy meals throughout the day.

The most common side effects of taking this medicine include headache, constipation, diarrhea, and weakness. Dizziness and sleepiness may also occur, so do not drive or do anything that requires mental focus until you know how this medicine affects you. These symptoms should disappear when you stop taking the medicine but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about any other medicine that you might be using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your healthcare team.

Uses of Grandem Tablet MD

  • Nausea and vomiting due to chemotherapy

Benefits of Grandem Tablet MD

In Nausea and vomiting due to chemotherapy

Grandem MD Tablet is used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. It blocks the action of chemicals in the body that can make you feel or be sick. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy.

Side effects of Grandem Tablet MD

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Grandem

  • Weakness
  • Headache
  • Constipation
  • Diarrhea
  • Insomnia (difficulty in sleeping)

How to use Grandem Tablet MD

Take this medicine in the dose and duration as advised by your doctor. Do not handle the tablets with wet hands. Put it in your mouth but do not swallow it. Grandem MD Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Grandem Tablet MD works

Grandem MD Tablet is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Grandem MD Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Grandem MD Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Grandem MD Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Grandem MD Tablet does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Grandem MD Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Grandem MD Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Grandem MD Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Grandem MD Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Grandem Tablet MD?

If you miss a dose of Grandem MD Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Grandem MD Tablet
₹3.7/Tablet MD
Granirex 1mg Tablet MD
Bennet Pharmaceuticals Limited
₹3.58/tablet md
3% cheaper
Grenitab MD Tablet
Kepran Healthcare
₹8.4/tablet md
127% costlier
Granivom 1mg Tablet MD
Leeford Healthcare Ltd
₹6.4/tablet md
73% costlier
Gramee-MD Tablet
Xenial Pharma
₹8.5/tablet md
130% costlier
Graniden 1mg Tablet MD
Welgenic Pharma
₹3.5/tablet md
5% cheaper

Quick tips

  • You have been prescribed Grandem MD Tablet for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
  • It is fast-acting and starts working within 30 minutes.
  • If you vomit within one hour of taking a dose, take another dose.
  • Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Fact Box

Chemical Class
Indazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Serotonin antagonists (5-HT3 antagonists)

Patient concerns

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NAUSEA AND VOMITING DUE TO COLD
Dr. Sunil Sekhri
Diabetology
Tab Domstal 1 tab Stat and keep yourself warm
Vomiting, nausea neck pain backside
Dr. Vijay Verma
ENT
Neck pain may be due to nausea NAD vomiting Visit physician for the same
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User feedback


FAQs

What is Grandem MD Tablet used for?

Grandem MD Tablet is an antiemetic medicine used to treat and prevent nausea or vomiting caused after any surgical procedure or due to certain medicines, stomach upset, or cancer treatment. It also prevents nausea due to motion sickness to some extent.

What are the side effects of Grandem MD Tablet?

The most common side effects of Grandem MD Tablet are sleepiness, weakness, headache, constipation and diarrhea. However, these are not usually bothersome and resolve in some time on their own. Consult your doctor, if the symptoms worry you or persist for a longer duration. Your doctor will suggest ways to cope up with these side effects and to prevent them in future.

Is Grandem MD Tablet safe to be used in pregnant women?

Grandem MD Tablet did not show any adverse effects in research studies done on animals. However, since the safety and efficiency of Grandem MD Tablet in pregnant women is unknown. It is not recommended to be used in women who are pregnant women or if you are planning to conceive unless prescribed by your doctor.

Is Grandem MD Tablet better than Ondansetron?

Grandem MD Tablet and Ondansetron belong to the same class of medicines, that is serotonin 5-HT3 receptor antagonists. Both these medicines help prevent nausea and vomiting effectively. However, some studies suggest that Grandem MD Tablet is more effective than Ondansetron. According to some reports, Grandem MD Tablet is comparatively well tolerated, quicker in action and alleviates nausea and vomiting relatively faster.

Does Grandem MD Tablet cause constipation?

Yes, Grandem MD Tablet may cause constipation as one of the common side effects. However, this is usually not bothersome. Taking a fiber-rich diet can enhance your digestion and avoid constipation. You may also consider taking laxatives for relief and drink plenty of water too. Avoid drinking alcohol as it may worsen your constipation. If you still face issues, please consult your doctor to know about ways to treat it.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Granisetron. Hertfordshire: Generics [UK] Limited; 2005 [revised Nov. 2018]. [Accessed on 28 Mar. 2018] (online) Available from:External Link
  2. Drugs.com. Granisetron Pregnancy and Breastfeeding Warnings. [Accessed 28 Mar. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link
Country of origin: India

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