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MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Grastim Injection


Product introduction

Grastim Injection is used to prevent infections after chemotherapy. It is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.

Grastim Injection is used after cancer treatment, if the level of white blood cells is too low, used to increase blood stem cells in the body or used after a bone marrow transplant

Uses of Grastim Injection

  • Prevention of Infections after chemotherapy

Benefits of Grastim Injection

In Prevention of Infections after chemotherapy

Grastim Injection increases the production of white blood cells by stimulating the immune system in our body. White blood cells are those cells that help us to fight infections. This medicine is really effective and must be used under medical supervision. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Side effects of Grastim Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Grastim

  • Bone pain
  • Weakness
  • Headache
  • Rash
  • Nausea
  • Increased lactate dehydrogenase level in blood
  • Vomiting
  • Increased uric acid level in blood
  • Oropharyngeal pain
  • Hair loss
  • Fatigue
  • Diarrhea
  • Constipation
  • Decreased appetite
  • Cough
  • Breathing problems
  • Injection site reactions (pain, swelling, redness)

How to use Grastim Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Grastim Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Grastim Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Grastim Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Grastim Injection may cause side effects which could affect your ability to drive.
Grastim Injection may cause fatigue. This may affect your driving ability.
Kidney
SAFE IF PRESCRIBED
Grastim Injection is safe to use in patients with kidney disease. No dose adjustment of Grastim Injection is recommended.
Liver
SAFE IF PRESCRIBED
Grastim Injection is safe to use in patients with liver disease. No dose adjustment of Grastim Injection is recommended.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Grastim Injection
₹618.8/Injection
₹2562.22/injection
314% costlier
Colstim Injection
Zydus Cadila
₹1271.92/injection
106% costlier
₹2800/injection
352% costlier
Granfill 300mcg Injection
Samarth Life Sciences Pvt Ltd
₹400/injection
35% cheaper
₹2443.68/injection
295% costlier

Quick tips

  • Grastim Injection reduces the risk of infection in people treated with chemotherapy.
  • It is usually given as a daily injection into the tissue just under the skin or into the vein. 
  • You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
  • Store it in the refrigerator, protect it from light, and don't shake it.
  • For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
  • Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
  • Use caution while driving or doing anything that requires concentration as Grastim Injection may cause dizziness.
  • Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
  • Stop taking Grastim Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.

Fact Box

Chemical Class
Granulocyte Colony-Stimulating Factor
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Granulocyte-colony stimulating factor (G-CSF)

Patient concerns

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Plz check the report and reply She is my wife report one of hospital where operated the tumot operation and one of from delhi srl and last one from tmh mumbai After the diagnosis docror advice rediation now 1 st rediation therapy is finished and doctor giving now nublast 250mg tab So plz check the report and tell me as per the tata memorial final report what is the condition for patient She can live normal life or she can dead in ahead Doctor tells with my family she can live with treatment more than 1 to 2 years Is it right or wrong
Dr. Vijay Sharnangat
Medical Oncology and Hematology
You are on right treatmentAfter completion of radiation therapy you need to take chemotherapyThat tablet is the chemotherapy
What is symptomatic after chemotherapy for metastatic spine
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Back pain is main symptom which you can get after disease progression
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FAQs

Is Grastim Injection safe?

Grastim Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

How does Grastim Injection work?

Grastim Injection works by stimulating the bone marrow (organ in the body where blood cells are produced) to increase the production of specific types of blood cells called neutrophils that help fight infections.

What are the uses of Grastim Injection?

Grastim Injection is used during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells called neutrophils), neutropenia in patients with HIV infection, and before stem cell donation.

Does Grastim Injection cause cancer?

No, Grastim Injection does not cause cancer.

Why does Grastim Injection cause bone pain?

The exact cause in unknown, but bone pain is a common side-effect of Grastim Injection.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1074-75.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 545-46.
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Filgrastim. [Updated 2019 Jun 3]. [Accessed 18 Feb. 2020] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Dr Reddy's Laboratories Ltd
Address: Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Country of origin: India

MRP
618.8
Inclusive of all taxes
1.0 ml in 1 vial
SOLD OUT
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