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Last updated
05 Dec 2023 | 06:14 PM (IST)

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Isokin 300 Tablet


Introduction of Isokin Tablet

Isokin 300 Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection. It also protects the nerves from the side effects that may occur during the course of the treatment.

Isokin 300 Tablet is a combination of mycolic acid inhibitors- INH and vitamin B6 (pyridoxine).

Uses of Isokin Tablet

Benefits of Isokin Tablet

In Tuberculosis (TB)

Isokin 300 Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. This medicine also contains nutritional supplements that improve functioning of the nerves. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Isokin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Isokin

  • Rash
  • Fever
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Jaundice

How to use Isokin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isokin 300 Tablet is to be taken empty stomach.
Avoid Isokin 300 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking Isokin 300 Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Isokin 300 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Isokin 300 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Isokin 300 Tablet may cause side effects which could affect your ability to drive.
Isokin 300 Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
Kidney
SAFE IF PRESCRIBED
Isokin 300 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Isokin 300 Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Isokin 300 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Isokin 300 Tablet may not be needed in these patients. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Isokin 300 Tablet
₹1.61/Tablet
Isocaldin 300 mg/10 mg Tablet
Retort Pharma Pvt Ltd
₹1.38/tablet
14% cheaper
Inatos 300mg/10mg Tablet
TOSC International Pvt Ltd
₹0.16/tablet
90% cheaper

Quick tips

Isokin Tablet

  • Isokin 300 Tablet should be taken on an empty stomach but at the same time every day.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Isokin 300 Tablet affects you.
  • Avoid consuming alcohol while taking this medication as it can enhance the dizziness.
  • Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI INFECTIVES

Patient concerns

Patient concerns

arrow
My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
Though took vaccines in childhood, the test for TB came positive. Was advised to undergo treatment.physically absolute fit and healthy, is it advisable to take treatment?
Dr. Anshum Aneja Arora
Pulmonology
If sputum is positive for Tb , treatment is absolutely essential. Read more at www.arohealth.com/tuberculosis
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 09 Apr. 2019] (online) Available from:External Link
  2. ScienceDirect. Pyridoxine. [Accessed 09 Apr. 2019] (online) Available from:External Link
  3. Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 09 Apr. 2019] (online) Available from:External Link
  4. MedlinePlus. Pyridoxine. [Accessed 09 Apr. 2019] (online) Available from:External Link

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