Key2fert-L Tablet helps treat breast cancer in post-menopausal women. It may be used alone or with other treatments, such as surgery or radiation. It can also be used in patients with advanced breast cancer to stop the tumor from spreading to other parts of the body.

Key2fert-L Tablet is also helpful in the treatment of infertility. It can be taken with or without food, but take it at about the same time to get the most benefit. The dose and frequency depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed.

This medicine's most common side effects include hot flashes, fatigue, increased sweating, and increased level of cholesterol (hypercholesterolemia). If these bother you or appear serious, let your doctor know. Your doctor may suggest ways to prevent or reduce these.

Before taking this medicine, tell your doctor if you have ever had liver or kidney disease, or have a history of osteoporosis (thinning or wasting of bones). Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may perform some blood tests to check for vitamin D level or bone density before and during treatment.

Uses of Key2fert-L Tablet

Treatment of Breast cancer
Treatment of Infertility due to anovulation

Benefits of Key2fert-L Tablet

In Treatment of Breast cancer

Key2fert-L Tablet relieves the symptoms of breast cancer such as breast lumps, bloody discharge from the nipple, or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer. It may also interact with other hormones or have a direct effect on cancer to stop its growth.

In Treatment of Infertility due to anovulation

Key2fert-L Tablet helps in the normal development of an egg in a woman's ovary (female reproductive organ) and stimulates the release of the egg during a process called ovulation. This helps to treat infertility in women. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective.

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Side effects of Key2fert-L Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Key2fert-L

Fatigue
Hypercholesterolemia (high cholesterol)
Increased sweating
Hot flashes

How to use Key2fert-L Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Key2fert-L Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Key2fert-L Tablet works

Key2fert-L Tablet is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estrogen can slow down or stop the growth of some breast cancers that need estrogen to grow. In addition, it is also useful in infertility whereby it increases the release of certain hormones to stimulate the release of eggs from the ovaries.

Safety advice

Alcohol

SAFE

Consuming alcohol with Key2fert-L Tablet does not cause any harmful side effects.

Pregnancy

UNSAFE

Key2fert-L Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

UNSAFE

Key2fert-L Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Key2fert-L Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Key2fert-L Tablet is safe to use in patients with kidney disease. No dose adjustment of Key2fert-L Tablet is recommended.
However, there is limited information on the use of this medicine in patients with end stage kidney disease. Please consult with your doctor.

Liver

CAUTION

Key2fert-L Tablet should be used with caution in patients with liver disease. Dose adjustment of Key2fert-L Tablet may be needed. Please consult your doctor.

What if you forget to take Key2fert-L Tablet?

If you miss a dose of Key2fert-L Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Key2fert-L Tablet

₹17.5/Tablet

Letronat Tablet

Natco Pharma Ltd

₹10.4/tablet

41% cheaper

Stimufol 2.5mg Tablet

Intas Pharmaceuticals Ltd

₹16.6/tablet

5% cheaper

Letroz Tablet

Sun Pharmaceutical Industries Ltd

₹20.6/tablet

18% costlier

Fempro Tablet

Cipla Ltd

₹3.6/tablet

79% cheaper

Mamazol Tablet

Khandelwal Laboratories Pvt Ltd

₹6/tablet

66% cheaper

View all substitutes

Quick tips

You have been prescribed Key2fert-L Tablet for the treatment of breast cancer or infertility due to anovulation.
It can be taken with or without food.
Do not drive or do anything requiring concentration until you know how Key2fert-L Tablet affects you.
It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Key2fert-L Tablet can alter their levels.
Do not take Key2fert-L Tablet if you are pregnant or breastfeeding

Fact Box

Chemical Class

Diphenylmethane Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Aromatase inhibitor

Patient concerns

Pain in nipple anytime . plz suggest PATIENT is my wife and she had an abortion in 2015 april

Dr. Suman Rao

Obstetrics and Gynaecology

Consult a breast specialist. Get Usg of b/l breasts done.

Swelling in face and pain in full body also allergy symptoms on skin like spots and its subside after sometimes.this is happing for last one week.

Dr. Kamal Rijhwani

Physician

Start cetiz l tablet

FAQs

Why have I been prescribed Key2fert-L Tablet?

Key2fert-L Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy. It is also used to treat infertility caused due to anovulation (during menstrual cycle egg cell from ovaries is not released).

How does Key2fert-L Tablet work?

Key2fert-L Tablet is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for the production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent cancer from growing.

For how long should I take Key2fert-L Tablet?

If the breast tumor is in the advanced stage or has spread to other parts of the body, it is recommended that you continue taking Key2fert-L Tablet till the tumor shows progression. In cases where Key2fert-L Tablet is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until the tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Key2fert-L Tablet followed by 3 years of tamoxifen.

If I am taking irbesartan to control my blood pressure, can I take Key2fert-L Tablet?

Yes, you can take irbesartan and Key2fert-L Tablet together. However, be careful and keep a regular check on your blood pressure since Key2fert-L Tablet may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.

Does Key2fert-L Tablet affect vision?

Although it is very uncommon, Key2fert-L Tablet may cause a cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.

My friend who is taking Key2fert-L Tablet often sweats a lot. Is it because of Key2fert-L Tablet?

This could be a sign of hot flushes which is a very common side effect of Key2fert-L Tablet. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Key2fert-L Tablet. However, in some people, the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.

What are the serious side effects of Key2fert-L Tablet?

The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Key2fert-L Tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis, and severe skin reactions.

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Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Related ayurvedic ingredients

Olive oil

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

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Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 786-87.
Drugs.com. Letrozole. [Accessed 03 Apr. 2019] (online) Available from:
Letrozole. Barnstaple, Devon: Accord-UK Ltd.; 2009 [revised 20 Nov. 2017]. [Accessed 25 Jan. 2019] (online) Available from:
Letrozole. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 1997 [revised Jan. 2014]. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.