Klotrim Injection is a combination medicine that is used to treat various types of bacterial infections such as pneumonia, bronchitis, infections of urinary tract, ear, and abdomen. It prevents the growth of microorganisms to cure the infection.

Klotrim Injection is a combination of two antibiotics: Klotrim Injection1 and Klotrim Injection2.

Uses of Klotrim Injection

Treatment of Bacterial infections

Benefits of Klotrim Injection

In Treatment of Bacterial infections

Infections caused by bacteria are known as bacterial infections. Klotrim Injection is an antibiotic which is used to treat different types of bacterial infections. Klotrim Injection works by stopping the growth of the bacteria. It is effective for bacterial infections of the lungs, throat, urinary tract, ear and stomach. It is advisable to continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed. Stopping it early may make the infection come back and difficult to treat.

Side effects of Klotrim Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Klotrim

Weight loss
Hives
Nausea
Vomiting
Increased potassium level in blood
Candida overgrowth
Headache
Rash
Diarrhea
Decreased appetite
Red spots or bumps

How to use Klotrim Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Klotrim Injection works

Klotrim Injection is a combination of two antibiotics: Sulfamethoxazole and Trimethoprim. These antibiotics work by preventing the bacteria from producing folic acid, a nutrient required for bacterial multiplication. Together, they treat your infection effectively.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Klotrim Injection.

Pregnancy

CONSULT YOUR DOCTOR

Klotrim Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Klotrim Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
There may be a possibility of skin rash in the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Klotrim Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Klotrim Injection should be used with caution in patients with kidney disease. Dose adjustment of Klotrim Injection may be needed. Please consult your doctor.
Use of Klotrim Injection is not recommended in patients with severe kidney disease.

Liver

CAUTION

Klotrim Injection should be used with caution in patients with liver disease. Dose adjustment of Klotrim Injection may be needed. Please consult your doctor.
Use of Klotrim Injection is not recommended in patients with the severe liver disease.

What if you forget to take Klotrim Injection?

If you miss a dose of Klotrim Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Klotrim Injection

₹100/Injection

Jolltrim 400mg/80mg Injection

Jolly Healthcare

₹200/injection

same price

Quick tips

You have been prescribed Klotrim Injection for the treatment of many types of bacterial infections.
Finish the prescribed course of Klotrim Injection, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
Stop taking Klotrim Injection and inform your doctor if you develop skin rash/blisters or other unexplained skin reaction while taking Klotrim Injection.
In case of long-term use, have regular monthly blood tests to monitor your blood cells as suggested by your doctor.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Patient concerns

Scar on face due to bacterial infections

Dr. Atul Jain

Dermatology

Pic is not clear, plz visit for proper opinion

I have a history of recurring yeast and bacterial vaginosis infections.

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days

FAQs

What is Klotrim Injection?

Klotrim Injection is a combination of two medicines: Sulfamethoxazole and Trimethoprim. It is an antibiotic which treats certain bacterial infections and works by stopping the growth of the bacteria causing the infection.

Can the use of Klotrim Injection cause nausea and vomiting?

Yes, the use of Klotrim Injection can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medication. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to a doctor.

Are there any specific contraindications associated with the use of Klotrim Injection?

Klotrim Injection is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine. It is also avoided in patients with a history of drug-induced immune thrombocytopenia (low platelet count), megaloblastic anemia caused due to folate deficiency. The medicine is also harmful for pediatric patients less than 2 months of age and for patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.

Can I stop taking Klotrim Injection when my symptoms are relieved?

No, do not stop taking Klotrim Injection and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.

What is the recommended storage condition for Klotrim Injection?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can I stop taking Klotrim Injection when I feel better?

No, do not stop taking Klotrim Injection and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

What if I miss my dose?

Take Klotrim Injection as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.

What if I don't get better after using Klotrim Injection?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

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Related lab tests

Complete Blood Count

Peripheral Smear Examination

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

MacDougall C. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1111-1126.
Chambers HF, Deck DH. Sulfonamides, Trimethoprim, & Quinolones. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 815-822.
Sulfamethoxazole and Trimethoprim [Package insert]. Kfar Saba, Israel: Teva Pharmaceutical Ind. Ltd.; 2013. [Accessed 16 Apr. 2021] (online) Available from:

Marketer details

Name: Gufic Bioscience Ltd

Address: 37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (INDIA)

Country of origin: India

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