Lisign 5 Tablet is widely used to treat high blood pressure and heart failure. It may also be prescribed after a heart attack. Additionally, it also lowers the chances of having a heart attack or stroke.

Lisign 5 Tablet is used to lower blood pressure (hypertension) and may prevent changes or damage to the heart and kidney.

Uses of Lisign Tablet

Hypertension (high blood pressure)
Prevention of heart attack and stroke
Heart failure

Benefits of Lisign Tablet

In Hypertension (high blood pressure)

Lisign 5 Tablet belongs to a group of medicines called ACE inhibitors. It reduces stress on the heart and relaxes the blood vessels. This widens the blood vessels and makes it easier for the heart to pump blood around your body, thereby lowering your blood pressure. Controlled blood pressure reduces the risk of having a heart attack, stroke, or kidney problems. The medicine must be taken regularly, as prescribed, to be effective. You do not usually feel immediate benefit from taking this medicine, however, it helps you maintain your blood pressure in the long term.

In Prevention of heart attack and stroke

Lisign 5 Tablet lowers your blood pressure. As a result, it reduces the chance of damage to the small blood vessels in your heart and kidneys. This reduces the risk of getting a heart attack and kidney problems. It also helps in slowing down the rate at which they get worse if you already have problems. This medicine must be taken regularly to be effective.

In Heart failure

Lisign 5 Tablet makes it easier for your heart to pump blood around your body so the heart has to do less work. This can improve your heart function and reduce the symptoms of heart failure. It will help improve your quality of life and enable you to go about your daily activities more efficiently. The medicine must be taken regularly and as long as the doctor has prescribed it to be effective.

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Side effects of Lisign Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lisign

Decreased blood pressure
Cough
Increased potassium level in blood
Fatigue
Weakness
Dizziness

How to use Lisign Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lisign 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Lisign 5 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Lisign 5 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Lisign 5 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Lisign 5 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Lisign 5 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lisign 5 Tablet may be needed. Please consult your doctor.
Regular monitoring of blood pressure is recommended for better dose adjustment.

Liver

CAUTION

Lisign 5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Lisign 5 Tablet may be needed. Please consult your doctor.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

What if you forget to take Lisign Tablet?

If you miss a dose of Lisign 5 Tablet, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Lisign 5 Tablet

₹1.65/Tablet

Listril 5 Tablet

Torrent Pharmaceuticals Ltd

₹6.03/tablet

265% costlier

Lipril 5 Tablet

Lupin Ltd

₹5.5/tablet

233% costlier

Hipril 5 Tablet

Micro Labs Ltd

₹3.75/tablet

127% costlier

Normopril 5mg Tablet

Aristo Pharmaceuticals Pvt Ltd

₹3.05/tablet

85% costlier

Lisitec 5mg Tablet

Cipla Ltd

₹1.03/tablet

38% cheaper

View all substitutes

Quick tips

Lisign 5 Tablet can make you feel dizzy for the first few days, so rise slowly if you have been sitting or lying down. You can also prefer taking it at bedtime to avoid dizziness throughout the day.
Let your doctor know about any cough, or throat irritation that does not go away.
It may increase the level of potassium in blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class

Dipeptides

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Angiotensin-converting enzyme (ACE) inhibitors

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FAQs

What is Lisign 5 Tablet? What is it used for?

Lisign 5 Tablet belongs to a group of medicines known as angiotensin-converting enzyme (ACE) inhibitors. It is used to treat high blood pressure (hypertension). It relaxes and widens the blood vessels, making it easier for the blood to pass through the vessels. As a result of this, the heart does not have to work more to push the blood. Since the workload on the heart is reduced, it helps to lower the blood pressure and thus reduces the risk of heart attack and stroke.

What should I tell my doctor before taking Lisign 5 Tablet?

Before taking Lisign 5 Tablet you must tell your doctor if you are allergic to Lisign 5 Tablet or any of its ingredients. You must tell the doctor if you have any problems related to heart, liver, kidneys (if you are on dialysis) or blood, such as a low white blood cell count (neutropenia or agranulocytosis). Inform your doctor if you have diabetes, irregular blood pressure or if you have recently had diarrhea or vomiting. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Consult your doctor before taking Lisign 5 Tablet if you are planning to conceive, if you are pregnant or breastfeeding to avoid any harmful effects on the baby.

What time of the day should I take Lisign 5 Tablet?

Lisign 5 Tablet should be taken at the same time each day to reduce the chances of a missed dose. Take it in the dose and duration prescribed by the doctor. Your doctor may advise you to take your first dose before bedtime, because it can make you dizzy. After the first dose, if you do not feel dizzy, you may take Lisign 5 Tablet at any time of the day. Your dose will depend on the condition you are being treated for and therefore, it will vary from person to person. If you experience any side effects while taking Lisign 5 Tablet, please consult your doctor.

I feel better after taking Lisign 5 Tablet, can I stop taking it?

No, continue taking Lisign 5 Tablet even if you feel better and your blood pressure is under control. Stopping Lisign 5 Tablet suddenly may cause your blood pressure to increase and your chances of stroke or heart attack may rise. Usually once you start taking any medicine for controlling blood pressure, you have to continue taking it life long unless you cannot tolerate it.

Will Lisign 5 Tablet make me feel dizzy? What should I do about it?

Yes, Lisign 5 Tablet may make you feel dizzy or lightheaded. If Lisign 5 Tablet makes you feel dizzy when you stand up, try getting up very slowly or stay seated until you feel better. If you begin to feel dizzy, lie down so that you don't faint, then sit until you feel better. Don’t drive, do not use tools or machines and avoid anything requiring concentration while you're feeling dizzy or shaky.

What other lifestyle changes should I make while taking Lisign 5 Tablet?

Lifestyle changes play a major role in keeping you healthy if you are taking Lisign 5 Tablet. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels and helps to keep your blood pressure normal. Stop smoking and alcohol consumption as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Lisign 5 Tablet and to keep yourself healthy.

I have diabetes. Does Lisign 5 Tablet have any effect on blood sugar levels?

Yes, Lisign 5 Tablet may have some effect on antidiabetic medicines or insulin and may lower your blood sugar levels. Therefore, you need to check your blood sugar levels regularly.

After starting Lisign 5 Tablet, I have developed dry cough which is very irritating and is not getting better with any medicine. What should I do now?

Lisign 5 Tablet may cause dry cough, as a side effect in some people. This can be persistent and may not be relieved by any medicine. Talk to your doctor if it bothers you or if you have trouble sleeping. Your doctor may suggest ways of managing the cough or may prescribe another medicine. Remember, do not stop taking Lisign 5 Tablet without consulting your doctor as it may increase your blood pressure and put you at a risk of developing a heart attack or stroke. Even if you stop taking Lisign 5 Tablet, the cough may take a few days to a month to resolve completely.

Can Lisign 5 Tablet affect my fertility?

There is no evidence that Lisign 5 Tablet has any effect on fertility in both men and women. However, if you are planning to get pregnant, consult your doctor first. This is because Lisign 5 Tablet is not recommended in pregnancy.

Can Lisign 5 Tablet increase potassium levels? If so, what should be done?

Lisign 5 Tablet may increase potassium levels in the blood, especially if you have uncontrolled diabetes mellitus, kidney problems and dehydration. Also, potassium levels may increase in patients who are using potassium salts or medicines or are aged more than 70 years of age. Therefore, if you have any of these conditions and are using Lisign 5 Tablet, be careful and get regular blood tests done to monitor potassium levels.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Hilal-Dandan R. Renin and Angiotensin. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 733.
Pfeffer MA, Opie LH. Inhibitors of the Renin-Angiotensin-Aldosterone System. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 144-45.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 807-809.
Drugs.com. Lisinopril Pregnancy and Breastfeeding Warnings. [Accessed 19 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Lisinopril. [Updated 2019 Feb 28]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

Marketer details

Name: Care Formulation Labs Pvt Ltd

Address: D-1659, DSIIDC, Narela Industrial Area, Delhi, 110040

Country of origin: India

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