Lofebril 50 Tablet is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is prescribed to treat depression, where it helps to make you feel better. This medicine is also used to treat people with obsessive-compulsive disorder.

Lofebril 50 Tablet is used to treat depression and Anxiety.

Uses of Lofebril Tablet

Benefits of Lofebril Tablet

In Depression

Lofebril 50 Tablet works by increasing the level of a chemical called serotonin in the brain. This improves your mood, relieves anxiety, tension, and helps you sleep better. It has fewer side effects than older antidepressants. It usually takes 4-6 weeks for this medicine to work so you need to keep taking it even if you feel it is not working. Do not stop taking it, even if you feel better unless your doctor advises you to.

In Obsessive-compulsive disorder

Lofebril 50 Tablet helps relieve symptoms of many anxiety disorders such as obsessive-compulsive disorder by increasing the level of a chemical called serotonin in your brain. It has fewer side effects than older antidepressants and is normally taken once a day. It helps you feel calm with a better ability to deal with problems. Exercise and a healthy diet can also improve your mood. Keep taking the medicine until your doctor advises you to stop.

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Side effects of Lofebril Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lofebril

Delayed ejaculation
Drowsiness
Erectile dysfunction
Low sexual desire
Nausea
Vomiting
Dryness in mouth
Fatigue
Increased sweating
Indigestion
Insomnia (difficulty in sleeping)
Loss of appetite
Nervousness
Tremors

How to use Lofebril Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lofebril 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Lofebril 50 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Lofebril 50 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Lofebril 50 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Lofebril 50 Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Lofebril 50 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Lofebril 50 Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Lofebril 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Lofebril 50 Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Lofebril 50 Tablet

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Quick tips

It should be taken at night with or without food.
Take caution while taking Lofebril 50 Tablet if you are using Benzodiazepines and MAO inhibitors previously.
Do not drive or do anything requiring concentration until you know how Lofebril 50 Tablet affects you.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class

Aralkylketone Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Selective Seretonin Reuptake inhibitors (SSRIs)

Patient concerns

Sir, I wont to take best medicine of Ayurveda for obsessive compulsive disorders(Depression)

Dr. Ankur Kumar Tanwar

Ayurveda

Use brahmi granules and jatamansi vati ,

Sir i am suffering from Anxiety, IBS and Obsessive compulsive disorder I want to how i get Ayurveda medicine

Dr. Aanchal Maheshwari

Ayurveda

You should contact Ayurvedic doctor in person before starting the treatment

My spouse (Age: 28 & Gender: F) suffering from Obsessive Compulsive Disorder (OCD). The activity of bathing & repeatedly cleaning of cloths & rooms. The Suggest me any medicine for him.

Dr. Saurav Arora

Homeopathy

Dear sir your problem can surely be treated with homeopathy but as your case is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly.

User feedback

Patients taking Lofebril 50 Tablet

Twice A Day

82%

Once A Day

18%

FAQs

Is Lofebril 50 Tablet used for anxiety?

Yes, Lofebril 50 Tablet is used to treat social anxiety disorder. It is anxiety related to interacting with others or performing in front of others that interferes with normal life. Lofebril 50 Tablet is also used for the treatment of the obsessive-compulsive disorder (OCD) and panic attacks. In OCD, a person experiences unwanted thoughts and the irresistible desire to perform certain actions over and over. These thoughts and desires do not go away and make it bothersome for the person.

Can Lofebril 50 Tablet get you high?

There is no evidence that Lofebril 50 Tablet causes dependence. But, patients may experience withdrawal symptoms on sudden discontinuation of Lofebril 50 Tablet. Usually, the withdrawal symptoms are mild and go away on their own within 2 weeks.

Who should not take Lofebril 50 Tablet?

You should not take Lofebril 50 Tablet if you are allergic to it, if you are taking another medicine to treat depression called a Monoamine Oxidase Inhibitor (MAOI), or if you have stopped taking an MAOI within the last 14 days. This is because taking both these medicines close in time together may cause serious and sometimes fatal reactions like high body temperature, convulsions, and even coma.

Does Lofebril 50 Tablet make you sleepy?

Yes, a common side effect of Lofebril 50 Tablet is sleepiness. It may also affect your ability to think clearly, make decisions, or react quickly. Avoid driving or operating heavy machinery until and unless you know how Lofebril 50 Tablet affects you.

Does Lofebril 50 Tablet have any serious health risks associated with it?

Yes, the use of Lofebril 50 Tablet may cause serious health risks. These may include increased risks of suicidal thoughts and actions, mania, bleeding problems, convulsions, visual problems, and low sodium levels in the blood.

How quickly does Lofebril 50 Tablet work?

It takes a long time for Lofebril 50 Tablet to start working. However, you may see an improvement in your sleep, appetite and energy levels within 1-2 weeks of starting Lofebril 50 Tablet. While, conditions like depressed mood and lack of interest in activities may take about 6-8 weeks to improve.

Can I stop Lofebril 50 Tablet if I am better now?

No, instead of stopping the medicine by yourself, consult your doctor who will gradually reduce the dose before stopping it completely. This is done because sudden discontinuation of Lofebril 50 Tablet may cause withdrawal symptoms. These symptoms include anxiety, irritability, high or low mood, feeling restless or changes in sleep habits, headache, sweating, nausea, dizziness, electric shock-like sensations, shaking, and confusion.

Does Lofebril 50 Tablet cause weight gain?

Lofebril 50 Tablet may either cause weight gain or weight loss. The weight loss could be due to loss of appetite. However, the chances of having weight gain or loss is not known. As compared to other anti-depressants, there is no significant change in body weight with Lofebril 50 Tablet in the majority of people.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Stahl SM, editor. Fluvoxamine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 269-74.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 578-81.
Fluvoxamine maleate. Jazz Pharmaceuticals; 1994 [revised 2008]. [Accessed 25 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
Fluvoxamine Tablets [Package Insert]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2014. [Accessed 03 Jul. 2023] (online) Available from:
Fluvoxamine maleate [Product Information]. Millers Point, NSW: Viatris Pty Ltd.; 2023. [Accessed 03 Jul. 2023] (online) Available from:

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