Makreb ED 30mg/40mg Capsule SR is a prescription medicine used to treat gastroesophageal reflux disease (Acid reflux) and indigestion by relieving the symptoms such as heartburn, stomach pain, or irritation. It also neutralizes the acid in the stomach and promotes easy passage of gas to reduce stomach discomfort.

Makreb ED 30mg/40mg Capsule SR is a combination of dopamine receptor antagonist and proton pump inhibitor.

Uses of Makreb ED Capsule SR

Benefits of Makreb ED Capsule SR

In Treatment of Gastroesophageal reflux disease (Acid reflux)

Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. Makreb ED 30mg/40mg Capsule SR reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.

Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

In Treatment of Functional dyspepsia

Functional dyspepsia is another term for indigestion that is not associated with a specific cause. It may cause symptoms such as an early feeling of fullness after eating, stomach pain or discomfort, nausea, and bloating. Makreb ED 30mg/40mg Capsule SR helps treat these symptoms by increasing the rate of stomach emptying. Follow your doctor’s instructions carefully and make appropriate lifestyle changes to get maximum benefit.

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Side effects of Makreb ED Capsule SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Makreb ED

Diarrhea
Flatulence
Stomach pain
Dryness in mouth
Headache

How to use Makreb ED Capsule SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Makreb ED 30mg/40mg Capsule SR is to be taken empty stomach.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Makreb ED 30mg/40mg Capsule SR. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Makreb ED 30mg/40mg Capsule SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Makreb ED 30mg/40mg Capsule SR is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Driving

UNSAFE

Makreb ED 30mg/40mg Capsule SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Makreb ED 30mg/40mg Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Makreb ED 30mg/40mg Capsule SR may be needed. Please consult your doctor.

Liver

CAUTION

Makreb ED 30mg/40mg Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Makreb ED 30mg/40mg Capsule SR may be needed. Please consult your doctor.
Use of Makreb ED 30mg/40mg Capsule SR is not recommended in patients with moderate and severe liver disease.

What if you forget to take Makreb ED Capsule SR?

If you miss a dose of Makreb ED 30mg/40mg Capsule SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Makreb ED 30mg/40mg Capsule SR

₹5.05/Capsule SR

Esomefol-DSR Capsule

Leeford Healthcare Ltd

₹3.52/capsule sr

30% cheaper

Es-omepraz -DSR Capsule

Alkem Laboratories Ltd

₹4.05/capsule sr

20% cheaper

Nexopil -DSR Capsule

Psychotropics India Ltd

₹3.75/capsule sr

26% cheaper

Nexpro RD 40 Capsule SR

Torrent Pharmaceuticals Ltd

₹7.72/capsule sr

53% costlier

Esofag-D Capsule SR

Micro Labs Ltd

₹8/capsule sr

58% costlier

View all substitutes

Quick tips

Makreb ED Capsule SR

You have been prescribed Makreb ED 30mg/40mg Capsule SR for the treatment of acidity and heartburn.
Take it one hour before the meal, preferably in the morning.
It is a well-tolerated medicine and provides relief for a long time.
Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Patient concerns

acid reflux, gastric, sugar stimulate acid reflux.

Dr. Pushkar Mani

Physician

CBC,ESR,LIPID PROFILE,URINE RE/CS, KFT, LFT, VIT D & B estimation,TAKE RABEKIND DSR once a day empty stomach FOR 3 week

Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers

Dr. Sunil Sekhri

Diabetology

You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed

FAQs

Makreb ED Capsule SR

What is Makreb ED 30mg/40mg Capsule SR?

Makreb ED 30mg/40mg Capsule SR is a combination of two medicines: Domperidone and Esomeprazole. This combination is used to treat acidity and heartburn or gastroesophageal reflux disease (GERD); a condition where the acid in the stomach flows back up into the food pipe (esophagus). It is also used to treat gastric and duodenal ulcers. Domperidone helps to control vomiting by increasing the movement of the gut, allowing the food to move more easily through the stomach.

Is it safe to use Makreb ED 30mg/40mg Capsule SR?

Yes, Makreb ED 30mg/40mg Capsule SR is safe for most of the patients. However, in some patients it may cause common side effects like diarrhoea, stomach pain, flatulence, dryness in mouth, dizziness, headache and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medicine.

What is the best time to take Makreb ED 30mg/40mg Capsule SR?

It is best to take Makreb ED 30mg/40mg Capsule SR before the first meal of the day or on an empty stomach.

Can the use of Makreb ED 30mg/40mg Capsule SR cause abnormal heartbeat?

Yes, the use of Makreb ED 30mg/40mg Capsule SR can increase the risk of irregular heartbeat (serious arrhythmias). This is a serious side effect but the chance that it may happen is very low. The risk may be slightly higher in those who are more than 60 years of age.

What are the contraindications associated with the use of Makreb ED 30mg/40mg Capsule SR?

The use of Makreb ED 30mg/40mg Capsule SR is considered to be harmful for patients with a known hypersensitivity to rabeprazole or domperidone or any other inactive ingredients of the medicine. Caution is advised in patients with underlying kidney or liver disease.

Can the use of Makreb ED 30mg/40mg Capsule SR cause dry mouth?

Yes, the use of Makreb ED 30mg/40mg Capsule SR can cause dry mouth. Dryness of mouth occurs due to Domperidone. If you experience dry mouth, drink plenty of water. Take regular sips of water during the day and keep some water on your bedside at night. Cut down the intake of alcohol and avoid smoking. If you have dry mouth, try to use alcohol-free mouthwash as its use can increase the risk of tooth decay.

Can the use of Makreb ED 30mg/40mg Capsule SR cause diarrhea?

Yes, the use of Makreb ED 30mg/40mg Capsule SR can cause diarrhea. In case of diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and if you notice signs of dehydration, like less frequency of urination and dark colored and strong-smelling urine. Avoid taking fatty or fried foods with this medication. Also, do not take any medicines without consulting the doctor.

What are the storage conditions for Makreb ED 30mg/40mg Capsule SR?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Top Physicians

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2003 [revised 14 Nov. 2017]. [Accessed 12 Apr. 2019] (online) Available from:
Esomeprazole. Luton, UK: AstraZeneca UK Ltd.; 2018. [Accessed 12 Apr. 2019] (online) Available from:
International Breastfeeding Center. Domperidone. [Accessed 12 Apr. 2019] (online) Available from:

Marketer details

Name: Maksal Pharmaceuticals (P) Ltd

Address: 117, 1st Floor, Essel House, 10 Asaf Ali Road, New Delhi-110002

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.