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MD Pharmacology, MBBS
Last updated
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Mefrin Forte 500mg/450mg Tablet

Prescription Required

Introduction of Mefrin Tablet

Mefrin Forte 500mg/450mg Tablet is a combination of two medicines. It is used in the treatment of fever. It is also useful for the treatment of mild to moderate pain of various conditions like headache, body ache, and toothache.

Mefrin Forte 500mg/450mg Tablet is a combination of two medicines: Mefrin Forte 500mg/450mg Tablet1 and Mefrin Forte 500mg/450mg Tablet2.

Uses of Mefrin Tablet

Benefits of Mefrin Tablet

In Pain relief

Mefrin Forte 500mg/450mg Tablet is a combination of medicines used to treat aches and pains. It blocks chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis and muscle aches.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time.

In Treatment of Fever

Mefrin Forte 500mg/450mg Tablet is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.

Side effects of Mefrin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mefrin

  • Nausea
  • Vomiting
  • Diarrhea
  • Indigestion
  • Loss of appetite
  • Heartburn

How to use Mefrin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mefrin Forte 500mg/450mg Tablet is to be taken with food.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Mefrin Forte 500mg/450mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Mefrin Forte 500mg/450mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Mefrin Forte 500mg/450mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Mefrin Forte 500mg/450mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Mefrin Forte 500mg/450mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Mefrin Forte 500mg/450mg Tablet may be needed. Please consult your doctor.
Use of Mefrin Forte 500mg/450mg Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Mefrin Forte 500mg/450mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Mefrin Forte 500mg/450mg Tablet may be needed. Please consult your doctor.
However, the use of Mefrin Forte 500mg/450mg Tablet is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Mefrin Tablet?

If you miss a dose of Mefrin Forte 500mg/450mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Mefrin Forte 500mg/450mg Tablet
₹1.25/Tablet
Elagesic Fort 500 mg/450 mg Tablet
Elan Pharma India Pvt Ltd
₹2.1/tablet
68% costlier
Spasmonil Forte Tablet
Cipla Ltd
₹0.88/tablet
30% cheaper
Eldospas Forte 500 mg/450 mg Tablet
Elder Pharmaceuticals Ltd
₹0.49/tablet
61% cheaper
Almefkem Forte 500mg/450mg Tablet
Alkem Laboratories Ltd
₹1.75/tablet
40% costlier
Mefnum Forte 500 mg/450 mg Tablet
Vintage Labs Pvt Ltd
₹1.4/tablet
12% costlier

Quick tips

Mefrin Tablet

  • Mefrin Forte 500mg/450mg Tablet is used to reduce pain and swelling in various conditions.
  • Take it with food to prevent an upset stomach.
  • It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
  • If you get diarrhea while taking this medicine, stop taking it and consult your doctor.
  • Avoid consuming alcohol while taking Mefrin Forte 500mg/450mg Tablet as it can cause excessive drowsiness and increase your risk of stomach problems.
  • Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
  • Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first. 
  • Mefrin Forte 500mg/450mg Tablet is used to reduce pain and swelling in various conditions.

Fact Box

Habit Forming
No
Therapeutic Class
PAIN ANALGESICS

Patient concerns

Patient concerns

arrow
fever and 2 months pregnant can take combiflan
Dr. Sonu Balhara Ahlawat
Obstetrics and Gynaecology
No take Crocin for pain relief
MORE
Diagnosed with viral fever along with rashes on the body. Pain in eyes since three days. Pain when open and when blinking.
Dr. Richa Jain
Ophthalmology
Orbital pain is common with viral fever. Go to physician for fever. It will be relieved with relief in fever
MORE
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FAQs

Mefrin Tablet

Is it safe to use Mefrin Forte 500mg/450mg Tablet?

Yes, Mefrin Forte 500mg/450mg Tablet is safe to use in most of the patients. However, in some patients it may cause some unwanted common side effects like nausea, vomiting, stomach pain, heartburn, diarrhea and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem due to the medication.

Can Mefrin Forte 500mg/450mg Tablet be stopped when the pain is relieved?

Mefrin Forte 500mg/450mg Tablet is usually used for short term and can be discontinued when the pain is relieved. However, if advised by the doctor, it should be continued for the recommended time period.

Can the use of Mefrin Forte 500mg/450mg Tablet cause nausea and vomiting?

Yes, the use of Mefrin Forte 500mg/450mg Tablet can cause nausea and vomiting. Taking it with milk, food or antacids can prevent nausea. Avoid taking fatty or fried foods along with the medicine. In the case of vomiting, drink plenty of water or other fluids by taking small and frequent sips. Talk to the doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to your doctor.

Can the use of Mefrin Forte 500mg/450mg Tablet cause dizziness?

Yes, the use of Mefrin Forte 500mg/450mg Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better. Do not drive or use any machines.

Are there any specific contraindications associated with the use of Mefrin Forte 500mg/450mg Tablet?

The use of Mefrin Forte 500mg/450mg Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcer or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with a history of liver or kidney disease.

Can I take Mefrin Forte 500mg/450mg Tablet with vitamin B-complex?

Yes, Mefrin Forte 500mg/450mg Tablet can be taken with Vitamin B-complex preparations. While Mefrin Forte 500mg/450mg Tablet helps to relieve pain, Vitamin B-complex can help correct the vitamin deficiency that might be causing the underlying painful condition.

Can the use of Mefrin Forte 500mg/450mg Tablet cause damage to kidneys?

Yes, the long-term use of Mefrin Forte 500mg/450mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protect the kidneys from damage. Use of painkillers lower the levels of prostaglandins in the body which leads to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Is it safe to take a higher than the recommended dose of Mefrin Forte 500mg/450mg Tablet?

No, taking a higher than the recommended dose of Mefrin Forte 500mg/450mg Tablet can increase the risks of side effects like nausea, vomiting, heartburn, indigestion, diarrhea and can also damage the kidneys on long-term use. If you are experiencing increased severity of pain or the pain is not relieved by the recommended doses, please consult your doctor for re-evaluation.

What are the storage condition for Mefrin Forte 500mg/450mg Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Related lab tests
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    Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

    References

    1. FDA approved prescribing information. Mefenamic Acid; 2008 [revised Mar. 2007]. [Accessed 02 Apr. 2019] (online) Available from:External Link
    2. ScienceDirect. Mefenamic Acid. [Accessed 02 Apr. 2019] (online) Available from:External Link
    3. ScienceDirect. Paracetamol/Acetaminophen. [Accessed 23 Apr. 2019] (online) Available from:External Link

    Marketer details

    Name: Rhine Biogenics Pvt Ltd
    Address: Rhine House, 21/555(3), Aditya Nagar, East Vennakkara, Nurani (P.O)
    Country of origin: India
    Expires on or after: February, 2025

    A licensed vendor partner from your nearest location will deliver Mefrin Forte 500mg/450mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

    In case of any issues, contact us

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