Author Details
Written By
MMST, MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Mestrolyst 40 Tablet


Product introduction

Mestrolyst 40 Tablet is used to treat breast cancer and endometrial cancer. It specifically helps treat breast and endometrial cancer that are hormone dependent. It may also be used for treating low appetite and weight loss in patients with advanced cancer or HIV.

It is a progestin.

Uses of Mestrolyst Tablet

Benefits of Mestrolyst Tablet

In Breast cancer

Mestrolyst 40 Tablet relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples, or changes in the shape or texture of the breast. It works by altering the production of those hormones in the body that are essential for the growth and spread of breast cancer. It may also interact with other hormones or have a direct effect on the cancer to stop its growth.

In Endometrial cancer

Mestrolyst 40 Tablet is a synthetic hormone which replicates the effect of a natural female hormone called progesterone. It relieves the symptoms of endometrial cancer (a type of cancer that develops in the lining of the womb) such as, abnormal vaginal bleeding, lower back pain, pain during sex, etc. It interferes with the production and working of those hormones in the body that are essential for the growth and spread of endometrial cancer. It may also interact with other hormones or have a direct effect on the cancer to stop its growth.

Side effects of Mestrolyst Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mestrolyst

  • Increased appetite
  • Weight gain
  • Hot flashes
  • High blood pressure
  • Constipation
  • Increased glucose level in blood

How to use Mestrolyst Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mestrolyst 40 Tablet may be taken with or without food, but it is better to take it at a fixed time.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Mestrolyst 40 Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Mestrolyst 40 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Mestrolyst 40 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Mestrolyst 40 Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Mestrolyst 40 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Mestrolyst 40 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Mestrolyst 40 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Mestrolyst 40 Tablet may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Mestrolyst 40 Tablet
₹12.5/Tablet
Endace 40 Tablet
Samarth Life Sciences Pvt Ltd
₹15.6/tablet
25% costlier
Megeetron 40mg Tablet
Alkem Laboratories Ltd
₹11.3/tablet
10% cheaper
Megahenz 40 Tablet
Alniche Life Sciences Pvt Ltd
₹12.5/tablet
same price
Megesym 40 Tablet
Symbion Lifescience
₹41.4/tablet
231% costlier
Appitral 40 Tablet
Zenska Life Sciences Pvt Ltd
₹25.5/tablet
104% costlier

Quick tips

  • Mestrolyst 40 Tablet is used to treat women with certain hormone-dependent cancers such as breast cancer and endometrial cancer.
  • It may also be used for treating appetite and weight loss in people with advanced cancer or AIDS.
  • You may have to take it for atleast 2 months before you notice any changes in your appetite.
  • Your doctor might do regular blood tests to check your hormones and blood sugar levels while you are taking this medicine.
  • Do not take Mestrolyst 40 Tablet if you are pregnant or breastfeeding.
  • Inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, severe headache, or changes in vision. These could be symptoms of a blood clot in a vein.
  • Do not stop taking the medicine suddenly without talking to your doctor first.

Fact Box

Chemical Class
Progesterone Congeners
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Progestins (First generation)

Patient concerns

arrow
If any symtom of brest cancer if have whats the cure
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer
BREAST CANCER , PET REPORT SAYS INFECTION IN SKELETON.
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Metastatic breast cancer, send me previous treatment details
arrow

FAQs

What is Mestrolyst 40 Tablet and what is it used for?

Mestrolyst 40 Tablet contains a medicine called Megestrol which is similar to the hormone progesterone, that naturally occurs in your body. It is used in hormone-dependent cancers of breast and endometrium (lining of the uterus). It may also be used to promote appetite and weight gain in AIDS patients.

Does Mestrolyst 40 Tablet make you gain weight?

Yes, Mestrolyst 40 Tablet may cause weight gain as a very common side effect. Weight gain could be due to an increase in appetite which leads to an overall increase in fat and body cell mass. Consult your doctor if you experience excessive weight gain. It is commonly used to treat malnutrition, loss of appetite and severe weight loss in patients with acquired immunodeficiency syndrome (AIDS). However, it is not intended for preventive use to avoid weight loss.

When should I take Mestrolyst 40 Tablet?

You can take Mestrolyst 40 Tablet at any time of the day. However, you should take it exactly as prescribed by your doctor. Swallow it whole with a glass of water. It can be taken with or without food, preferably at the same time each day since this helps you to remember taking it. Check with your doctor if you are not sure.

Does Mestrolyst 40 Tablet stop periods?

No, Mestrolyst 40 Tablet does not stop periods. However, it may interfere with your normal menstrual cycle. It may cause break-through bleeding and therefore has limited use in HIV infected women. Consult your doctor in case you experience breakthrough bleeding during the treatment with Mestrolyst 40 Tablet.

Is Mestrolyst 40 Tablet a chemo medicine?

No, Mestrolyst 40 Tablet is not a chemo medicine. It is a man-made version of the progesterone hormone. It is helpful in the treatment of breast cancer and endometrial cancer (cancer of the uterus). It works by modifying the female hormones involved in cancer growth.

Is Mestrolyst 40 Tablet acetate safe to be taken during pregnancy?

No, you should not take Mestrolyst 40 Tablet if you are pregnant or are planning a pregnancy. However, if you become pregnant while taking Mestrolyst 40 Tablet, immediately contact your doctor as Mestrolyst 40 Tablet may cause harm to your unborn baby. It is important to inform the doctor because it may cause abnormalities of sex organs in male and female babies if it is taken during first 3 months of pregnancy. Usually, the doctor may suggest a pregnancy test before starting your treatment with Mestrolyst 40 Tablet.

Does Mestrolyst 40 Tablet prevent pregnancy?

No, Mestrolyst 40 Tablet does not prevent pregnancy. It may disrupt your normal menstrual cycle but does not prevent pregnancy. Hence, you should use a reliable method of birth control to prevent pregnancy. Check with your doctor in case you are not sure or have any doubts.

What is Mestrolyst 40 Tablet? What is it used for?

Mestrolyst 40 Tablet contains Megestrol, which is similar to the naturally produced hormone progesterone. The medicine is used in treatment hormone-dependent cancers of breast and endometrium (lining of the uterus). It may also be used to promote appetite and weight gain in AIDS patients.

Does Mestrolyst 40 Tablet need to be refrigerated?

No, there is no need to refrigerate Mestrolyst 40 Tablet. However, this medicine should not be stored above 25°C. It should be stored in original packaging to protect from moisture.

Is Mestrolyst 40 Tablet used for hot flashes?

Use of Mestrolyst 40 Tablet in hot flashes is not approved. Always consult your doctor before using Mestrolyst 40 Tablet. Usually, estrogen in women and androgen in men are used for the treatment of hot flashes but these hormones cannot be used in females with breast cancer and males with prostate cancer.

Related ayurvedic ingredients

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Medsacpe. Megestrol. [Accessed 03 Apr. 2019] (online) Available from:External Link
  2. Megestrol. Spring Valley, New York: Par Pharmaceutical Companies, Inc.; 1993 [revised May 2013]. [Accessed 03 Apr. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Septalyst Lifesciences Pvt.Ltd.
Address: P-109, Jai Mata Di Complex, Opp Ranbaxy Laboratories,Kalhar Bhiwandi , Thane Maharashtra -421 302
Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.

125
Inclusive of all taxes
MRP249  50% OFF
10.0 tablets in 1 strip
SOLD OUT
Notify me
Available options
Available options
Same salt composition:Megestrol (40mg)
https://onemg.gumlet.io/epf1dtoymcv3sbkzuspl.png
Same salt composition
https://onemg.gumlet.io/qkdhgo7ram1mle08cya9.png
Verified by doctors
https://onemg.gumlet.io/ehvn8wef9oaoewteak8d.png
Popularly bought
https://onemg.gumlet.io/xnv1s7snefeql2hkalfr.png
Trusted quality
Why buy these from 1mg?question-mark

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.