Metraff 500 SR Tablet is a medicine used to treat type 2 diabetes mellitus. It helps control blood sugar levels and thus prevent serious complications of diabetes. It is also used to treat a menstruation-related disorder known as Polycystic ovary syndrome (PCOS) in women.

Metraff 500 SR Tablet is best taken with food to avoid nausea and abdominal pain. You should take it regularly, at the same time each day, to get the most benefit. You should not stop taking this medicine unless your doctor recommends it. Your lifestyle plays a big part in controlling diabetes. Therefore, it is important to stay on the diet and exercise program recommended by your doctor while taking this medicine.

The most common side effects of this medicine include nausea, vomiting, taste change, diarrhea, abdominal pain, and loss of appetite. Some people may develop hypoglycemia (low blood sugar level) when this medicine is taken along with other antidiabetic medicines, alcohol, or upon skipping a meal. Monitor your blood sugar levels regularly while taking it.

Before taking this medicine, inform your doctor if you have any kidney, liver, or heart problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Your doctor will check your kidney function tests before starting treatment with it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Metraff Tablet SR

Side effects of Metraff Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Metraff

Nausea
Vomiting
Taste change
Diarrhea
Abdominal pain
Loss of appetite

How to use Metraff Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metraff 500 SR Tablet is to be taken with food.

How Metraff Tablet SR works

Metraff 500 SR Tablet is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Metraff 500 SR Tablet.

Pregnancy

SAFE IF PRESCRIBED

Metraff 500 SR Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Metraff 500 SR Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

CAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

CAUTION

Metraff 500 SR Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metraff 500 SR Tablet may be needed. Please consult your doctor.
Use of Metraff 500 SR Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Liver

CAUTION

Metraff 500 SR Tablet should be used with caution in patients with liver disease. Dose adjustment of Metraff 500 SR Tablet may be needed. Please consult your doctor.
Metraff 500 SR Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

What if you forget to take Metraff Tablet SR?

If you miss a dose of Metraff 500 SR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Metraff 500 SR Tablet

₹1.55/Tablet SR

Glycomet 500 SR Tablet

USV Ltd

₹1.08/tablet sr

30% cheaper

Glyciphage SR 500mg Tablet

Franco-Indian Pharmaceuticals Pvt Ltd

₹1.07/tablet sr

31% cheaper

Gluconorm SR 500mg Tablet

Lupin Ltd

₹1.86/tablet sr

20% costlier

Obimet SR Tablet

Corona Remedies Pvt Ltd

₹1.07/tablet sr

31% cheaper

Metsmall 500 Tablet SR

Dr Reddy's Laboratories Ltd

₹0.88/tablet sr

43% cheaper

View all substitutes

Quick tips

You have been prescribed Metraff 500 SR Tablet to control the blood sugar level and reduce the risk of diabetic complications such as heart attacks.
Chances of weight gain and low blood sugar are lesser with this medicine as compared to other diabetes medicines.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Metraff 500 SR Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Prolonged use of Metraff 500 SR Tablet may lead to vitamin B12 deficiency which may lead to anemia, causing fatigue, pale skin, shortness of breath or headache. Notify your doctor if you experience any of these as you may require supplements.
Your doctor will monitor your blood sugar levels and kidney functions regularly while you are taking this medication.

Fact Box

Chemical Class

Biguanides Derivative

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Biguanides

Patient concerns

Dr. Sir, I have facing depression again after 2 year , and I don't know what was it's triggered point. Kindly tell me what should i do in this situation, I am bachelor. Is Zyven is good for this situation as it was earlier suggest by psychiatrist.

Dr. Jyoti Kapoor Madan

Psychiatry

Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.

Hysterectomy ovaries removed body ache night sweats

Dr. Megha Gupta

Obstetrics and Gynaecology

Such problems are common after getting ovaries removed. Do not worry, these problems will eventually fade with time. However if it causes discomfort and restlessness, you should see your gynaecologist for hormonal replacement therapy

Sugar is above 300 for past 4years Due to that couldn't able to walk without walker blood has clotted in brain

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

FAQs

What does Metraff 500 SR Tablet do exactly?

People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Metraff 500 SR Tablet acts in several ways to reduce the increased levels of sugar in blood. Metraff 500 SR Tablet decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.

Does Metraff 500 SR Tablet cause weight loss?

Yes, Metraff 500 SR Tablet has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.

What are the benefits of taking Metraff 500 SR Tablet?

Metraff 500 SR Tablet is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Metraff 500 SR Tablet when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.

Can Metraff 500 SR Tablet make you sleepy?

Metraff 500 SR Tablet usually does not cause sleepiness and is well tolerated. However, the use of Metraff 500 SR Tablet may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Metraff 500 SR Tablet.

How to take Metraff 500 SR Tablet?

Take Metraff 500 SR Tablet with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Metraff 500 SR Tablet with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1258-60.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 741-42.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 873-75.
Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 12 Mar. 2019] (online) Available from:
Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 12 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:

Country of origin: India

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