legitscript-image
We are
Legitscript Certified
Click to Know More
Author Details
Written By
Dr. Radhika Dua
MDS, BDS
Reviewed By
Dr. Shilpa Garcha
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Mext 15 Tablet

Prescription Required
arrow
arrow

Product introduction

Mext 15 Tablet is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It is also used to treat rheumatoid arthritis, severe and uncontrolled psoriasis, and Crohn’s disease.

It is an antimetabolite

Uses of Mext Tablet

Benefits of Mext Tablet

In Treatment of Cancer

Mext 15 Tablet works by slowing the growth of cancer cells in the body. It is used to treat a wide range of cancers such as acute leukemias, non-Hodgkin’s lymphoma, and solid tumors found in breast, lung, bladder, head and neck as well as cervical, ovarian and testicular cancer. It may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Treatment of Rheumatoid arthritis

Mext 15 Tablet belongs to a group of medicines called antimetabolites. It may be used to treat severe rheumatoid arthritis if other treatments have already been tried and have not worked. It is not a first-line treatment. It works by reducing the body's immune system, this decreases swelling, reduces pain, stiffness, and improves function. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. Do not take more than you should. It may take several months to become fully effective.

In Treatment of Psoriasis

Mext 15 Tablet belongs to a group of medicines called antimetabolites. It may be used to treat severe psoriasis when other treatments have not worked. Psoriasis is a condition where the skin cells in the body grow too quickly. Mext 15 Tablet works by killing these fast-growing cells. It is potent and very toxic medicine and you should discuss the risks and benefits with your doctor. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. DO NOT take more than you should. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Treatment of Crohn’s disease

Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines. The most common symptoms are diarrhea and pain in your abdomen. Mext 15 Tablet helps reduce the inflammation, relieve the symptoms, and prevent them from coming back.

Side effects of Mext Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mext

  • Ulcerative stomatitis
  • Nausea
  • Abdominal pain
  • Increased liver enzymes
  • Hair loss
  • Decreased blood cells (red cells, white cells, and platelets)

How to use Mext Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mext 15 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Mext Tablet works

Mext 15 Tablet inhibits enzymes (dihydrofolate reductase), prevents cell division and leads to anti-inflammatory actions. Mext 15 Tablet kills cancer cells by preventing them from making DNA. Mext 15 Tablet can help control psoriasis by retarding the production of skin cells and suppressing inflammation. Mext 15 Tablet may treat rheumatoid arthritis by suppressing the immune system, preventing it from attacking the body's cells. This helps reduce the inflammation that causes swollen and stiff joints in rheumatoid arthritis, or damage to bowel in Crohn's disease.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Mext 15 Tablet.
Pregnancy
UNSAFE
Mext 15 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Mext 15 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Mext 15 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Mext 15 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Mext 15 Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Mext 15 Tablet should be used with caution in patients with liver disease. Dose adjustment of Mext 15 Tablet may be needed. Please consult your doctor.

What if you forget to take Mext Tablet?

If you miss a dose of Mext 15 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Mext 15 Tablet
₹15.4/Tablet
Folitrax 15 Tablet
Ipca Laboratories Ltd
₹19.4/tablet
26% costlier
Meditrex 15mg Tablet
Overseas Healthcare Pvt Ltd
₹10.7/tablet
31% cheaper
Rhutrax 15mg Tablet
Rhumasafe Pharmaceutical
₹12.5/tablet
19% cheaper
Mexate 15 Tablet
Zydus Cadila
₹42.5/tablet
176% costlier
Leetrexate 15mg Tablet
Johnlee Pharmaceuticals Pvt Ltd
₹27.4/tablet
78% costlier

Quick tips

  • Drink plenty of liquids to stay hydrated while taking this  medication.
  • Take folic acid if advised by your doctor. This will help lessen the side effects of this medicine.
  • It may take from weeks to months for Mext 15 Tablet to work. Keep taking the medication as prescribed.
  • Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood.
  • Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects.
  • It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.

Fact Box

Chemical Class
Glutamic Acid Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolite- Methotrexate

Patient concerns

arrow
from last one year having psoraiasis disease consulted doctor before 7 months they prescribed medicens -TECZINE 5mg -MEXT 7.5 F and creams- from last one year having psoriasis disease consulted doctor they prescribed medicines like psoriasis disease frm one yr,doctor prescribed MEXT 7.5F TUCZINE 5mg emolene & calpsor creams
Dr. Banashree Majumdar
Dermatology
Dear Mr PATIENT can understand your problem but you need to understand that psoriasis is a chronic disease with propensity to spread, with a waxing waning course which is quite unpredictable. You may require some oral medications apart from topical. You need to visit nearby dermatologist personally you are intelligent enough to understand the fact that we cannot prescribe any medication which have a lot of side effects online, as it can harm you.
MORE
My mother has rheumatoid arthritis and she is prescribed with mext 7.5 f with proxym 300 shall she continue taking these tablets and can she take Etova 300mg instead of proxym 300
Dr. Akshat Goel
Orthopaedics
Etova will be better Add tab Saaz 500mg twice daily
MORE
arrow

User feedback

FAQs

Can Mext 15 Tablet cause mouth ulcers?

Yes, Mext 15 Tablet can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.

Why do I have to take folic acid with Mext 15 Tablet?

Folic acid is required to make new cells in the body and Mext 15 Tablet decreases the folic acid levels in the body. Folic acid can help reduce some of the common side effects of Mext 15 Tablet such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems.

Why do I need to take regular blood tests while taking Mext 15 Tablet?

Regular blood tests will help your doctor to check your response to Mext 15 Tablet and monitor you for side effects. You will need to regularly check your liver function and your blood counts (white blood cells, red blood cells and platelets). Your doctor may also order additional tests depending on the results.

Can Mext 15 Tablet use make me more prone to infections?

Mext 15 Tablet may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports which suggest occurrence of serious lung infections with Mext 15 Tablet use. If you have an active infection, Mext 15 Tablet should be used with extreme caution.

Can Mext 15 Tablet affect fertility?

Yes, Mext 15 Tablet may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry, these effects are reversible and disappear once the therapy is discontinued.

What to do if I am planning to become pregnant and my husband is taking Mext 15 Tablet?

You should avoid pregnancy if your husband is taking Mext 15 Tablet. Also, it is advised that pregnancy should be further avoided for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.
Related lab tests
  • Anti Saccharomyces Cerevisiae (ASCA), IgA
  • Anti Saccharomyces Cerevisiae (ASCA), IgG
  • Rheumatoid Factor - Agglutination
  • Rheumatoid Factor - Turbidometry
  • Rheumatoid Factor IgG Antibody

    • Related ayurvedic ingredients

    Want to share the information?

    Disclaimer:

    Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

    References

    1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.
    2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.
    3. Methotrexate [Prescribing Information]. Eatontown, NJ: West-Ward Pharmaceuticals Corp.; 2020. [Accessed 19 Apr. 2023] (online) Available from: External Link
    4. Methotrexate [Product Label]. New York, NY: Pfizer Inc.; 2022. [Accessed 19 Apr. 2023] (online) Available from:External Link
    5. Methotrexate [Drug Label]. Sandton, South Africa: Pfizer Laboratories (Pty) Ltd.; 2022 [Accessed 19 Apr. 2023] (online) Available from:External Link
    6. Walfish AE, Companioni RA. Drugs for Inflammatory Bowel Disease. [Updated Sep. 2022]. [Accessed 19 Apr. 2023] (online) Available from:External Link
    7. Crohn's & Colitis, UK. Methotrexate [Information Sheet]. [Accessed 19 Apr. 2023] (online) Available from:External Link
    8. CiplaMed. Methotrexate [Prescribing Information]. [Last Reviewed: Feb 2019]. [Accessed 11 Jul. 2023]. (online) Available from:External Link

    Marketer details

    Name: Wallace Pharmaceuticals Pvt Ltd
    Address: Wallace Pharmaceuticals Pvt. Ltd., 3rd Floor, Dempo Trade Centre Bldg., Patto Plaza, EDC Complex, Panaji 403001, Goa, India.
    Country of origin: India
    Expires on or after: February, 2025

    A licensed vendor partner from your nearest location will deliver Mext 15 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

    In case of any issues, contact us

    Email ID: [email protected]
    Phone Number: 0124-4166666
    Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
    ₹130.9₹307Get 57% OFF
    ₹123.2+ free shipping withCare Plan Logo
    Inclusive of all taxes
    Get this discount by applying coupon 1MGALL on the cart. Max. coupon discount is ₹380. T&C apply.
    1 Strip
    10.0 tablets in 1 strip
    Add to cart

    INDIA’S LARGEST HEALTHCARE PLATFORM

    260m+
    Visitors
    31m+
    Orders Delivered
    1800+
    Cities
    Get the link to download App

    Connect

    • Social Links
    • Want daily dose of health?
    Download App
    Reliable

    All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

    Secure

    Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

    Affordable

    Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

    LegitScript approved
    India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

    Know more about Tata 1mgdownArrow

    Access medical and health information

    Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

    Order medicines online

    Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

    Book lab tests

    Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

    Consult a doctor online

    Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.

    © 2024 Tata 1mg. All rights reserved. All medicines are dispensed in compliance with the Drugs and Cosmetics Act, 1940 and Drugs and Cosmetics Rules, 1945. We do not process requests for Schedule X and habit forming drugs.