Myostigmin 0.5mg Injection 1ml is a prescription medicine used in the treatment of myasthenia gravis (a disease-causing muscle weakness and tiredness), paralytic ileus (paralysis of intestinal muscles), postoperative urinary retention, and for reversal of effect of skeletal muscle relaxants after surgery.

Myostigmin 0.5mg Injection 1ml improves nerve activity.

Uses of Myostigmin Injection

Treatment of Myasthenia gravis
Treatment of Paralytic ileus
Treatment of Post-operative urinary retention
Reversal of effect of skeletal muscle relaxant after surgery

Benefits of Myostigmin Injection

In Treatment of Myasthenia gravis

Myasthenia gravis is a neuromuscular disorder that leads to weakness of muscles that are under our control, such as those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking. It happens due to impaired coordination between muscles and nerves. Myostigmin 0.5mg Injection 1ml makes this coordination between nerves and muscles better and relieves the symptoms. As a result, your muscle strength is improved and you are able to lead a better life.

In Treatment of Paralytic ileus

Paralytic ileus is the obstruction of the intestines due to improper functioning of the nerves and muscles in the intestine that impairs digestive movement. Myostigmin 0.5mg Injection 1ml induces contractions in the intestinal muscles and improves their function. As a result, there is better movement of food and this treats the obstruction. Take it as advised by the doctor and follow your doctor’s instructions carefully.

In Treatment of Post-operative urinary retention

After an operation, there may be problems in emptying the bladder. This may be due to disturbed coordination of nerves and muscles of the bladder. Myostigmin 0.5mg Injection 1ml helps to improve this problem and treats postoperative urinary retention effectively.

In Reversal of effect of skeletal muscle relaxant after surgery

Skeletal muscle relaxants are given to induce anesthesia and to carry out surgical or certain diagnostic procedures. This blocks the conduction of signals between nerves and muscles. After the surgery, Myostigmin 0.5mg Injection 1ml is given to reverse this effect and cause muscle contraction again to restore normal function.

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Side effects of Myostigmin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Myostigmin

Nausea
Vomiting
Slow heart rate

How to use Myostigmin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol

UNSAFE

Myostigmin 0.5mg Injection 1ml may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Myostigmin 0.5mg Injection 1ml may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Myostigmin 0.5mg Injection 1ml is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Myostigmin 0.5mg Injection 1ml alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Myostigmin 0.5mg Injection 1ml should be used with caution in patients with kidney disease. Dose adjustment of Myostigmin 0.5mg Injection 1ml may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may advised while you are taking this medicine.

Liver

SAFE IF PRESCRIBED

Myostigmin 0.5mg Injection 1ml is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Myostigmin 0.5mg Injection 1ml may not be needed in these patients. Please consult your doctor.

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For informational purposes only. Consult a doctor before taking any medicines.

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Quick tips

It is given into veins, muscles or under the skin by a healthcare professional.
Do not drink alcohol while taking this medicine as it may worsen the side effects.
Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.

Fact Box

Chemical Class

Phenoxy Compounds

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Cholinesterase inhibitors- carbamates

Patient concerns

Drooping of eyelids. What is the cause of it? What is the remedy?

Dr. Vishal Maniar

Ophthalmology

At ur age u need detailed eye checkup and neurologist referenceTo rule out myasthenia gravis, ocular palsy Bells palsy,diabetes,trauma

Right medicine for myasthenia gravis

Dr. Vikas Sharma

Neurology

many ; cant advise online as they are strong medicine

FAQs

Does Myostigmin 0.5mg Injection 1ml treat myasthenia gravis? How long do I need to take it?

Myostigmin 0.5mg Injection 1ml relieves the symptoms of myasthenia gravis but does not cure it. It does so by reducing and improving muscle weakness. The length of time for which you need to take Myostigmin 0.5mg Injection 1ml will depend on your condition. Do not stop taking Myostigmin 0.5mg Injection 1ml until and unless advised by your doctor, even if you start feeling better.

How long does Myostigmin 0.5mg Injection 1ml take to start working?

Myostigmin 0.5mg Injection 1ml takes about 5 to 15 minutes to start working and remains effective for 2-4 hours.

Is Myostigmin 0.5mg Injection 1ml a steroid?

No, Myostigmin 0.5mg Injection 1ml is not a steroid. It belongs to cholinesterase inhibitor group of medicines. Myostigmin 0.5mg Injection 1ml work by preventing the breakdown of a chemical called acetylcholine.

Does it cause weight gain?

No, Myostigmin 0.5mg Injection 1ml does not cause weight gain. Your weight gain may be due to inactivity related to muscle weakness in myasthenia gravis.

Is Myostigmin 0.5mg Injection 1ml safe to use?

Yes, Myostigmin 0.5mg Injection 1ml is safe if used in the dose and duration prescribed by the doctor.

I felt better when I started taking Myostigmin 0.5mg Injection 1ml but I have noticed recently that I get tired easily and quickly. Will increasing the dose help me?

If your symptoms have started reappearing, then it could be due to increased severity of myasthenia gravis or excess dose of Myostigmin 0.5mg Injection 1ml. Both the conditions have similar effects, so it becomes very difficult to differentiate between the two. Do not increase the dose on your own and consult your doctor immediately.

Can I take Myostigmin 0.5mg Injection 1ml for constipation?

No, Myostigmin 0.5mg Injection 1ml should not be taken for any type of constipation. However, its use is limited to cases of constipation caused by paralysis of intestine and strictly on prescription by the doctor.

What should I do if I accidentally take more than the dose required?

You should seek immediate medical help in case of overdose of Myostigmin 0.5mg Injection 1ml.Excess of Myostigmin 0.5mg Injection 1ml may cause stomach pain, nausea, vomiting, diarrhea, blurred vision, difficulty in breathing, and excessive sweating, salivation, and weakness. It can even lead to paralysis.

Does Myostigmin 0.5mg Injection 1ml have any abuse potential?

No, there is no evidence of Myostigmin 0.5mg Injection 1ml having any abuse potential.

Who should not take Myostigmin 0.5mg Injection 1ml?

Myostigmin 0.5mg Injection 1ml should not be taken by patients who are allergic to it. Patients who are constipated or cannot urinate should avoid its use, unless advised by the doctor. This is because Myostigmin 0.5mg Injection 1ml is only used for certain types of urination problems and constipation (e.g. caused by paralysis of intestine).

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 969.
Drugs.com. Neostigmine Pregnancy and Breastfeeding Warnings. [Accessed 25 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Neostigmine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Neostigmine. Gloucester Business Park, Gloucester: Hameln Pharmaceuticals Ltd.; 2001 [revised 12 Jan. 2018]. [Accessed 25 Mar. 2019] (online) Available from:
Neostigmine Methylsulfate Injection [FDA Label]. Chesterfield, MO: Éclat Pharmaceuticals; 2013. [Accessed 24 Sept. 2020]. (online) Available from:

Marketer details

Name: Neon Laboratories Ltd

Address: 140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.

Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Myostigmin 0.5mg Injection 1ml. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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