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MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:15 PM (IST)

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Nexchio 40mg Capsule


Product introduction

Nexchio 40mg Capsule is used to treat conditions related to excessive stomach acid production, such as gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger-Ellison syndrome. It reduces the amount of acid produced in the stomach and provides relief from symptoms and promotes healing.

Nexchio 40mg Capsule relieves heartburn and helps in healing ulcers.

Uses of Nexchio Capsule

Benefits of Nexchio Capsule

In Treatment of Gastroesophageal reflux disease (Acid reflux)

GERD is a chronic (long-term) condition that is like having heartburn consistently rather than just occasionally. It happens because a muscle above your stomach relaxes too much and allows stomach contents to come back up into your esophagus and mouth. Nexchio 40mg Capsule belongs to a group of medicines called proton pump inhibitors. It reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.

Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

In Treatment of Peptic ulcer disease

Nexchio 40mg Capsule belongs to a group of medicines called proton pump inhibitors. It reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.

In Treatment of Zollinger-Ellison syndrome

Zollinger-Ellison syndrome is a rare disorder where excessive stomach acid production leads to multiple peptic ulcers. Symptoms include abdominal pain, diarrhea, and heartburn. Nexchio 40mg Capsule By reducing the production of stomach acid, it helps alleviate symptoms such as abdominal pain, heartburn, and diarrhea. Esomeprazole also aids in the healing of peptic ulcers, which are common in this condition. By controlling the excessive acid secretion associated with Zollinger-Ellison syndrome, esomeprazole helps improve the overall digestive health and prevents complications such as gastrointestinal bleeding.

Side effects of Nexchio Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nexchio

  • Headache
  • Dryness in mouth
  • Nausea
  • Abdominal pain
  • Constipation
  • Flatulence
  • Diarrhea

How to use Nexchio Capsule

Take this medicine in the dose and duration as advised by your doctor. Nexchio 40mg Capsule is to be taken empty stomach.

How Nexchio Capsule works

Nexchio 40mg Capsule is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Nexchio 40mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Nexchio 40mg Capsule during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Nexchio 40mg Capsule during breastfeeding is not available. Please consult your doctor.
Caution should be exercised when Nexchio 40mg Capsule is administered to breastfeeding women.
Driving
UNSAFE
Nexchio 40mg Capsule may cause side effects which could affect your ability to drive.
In rare cases, Nexchio 40mg Capsule may cause dizziness and blurred vision, do not drive or use machines if you experience such symptoms.
Kidney
SAFE IF PRESCRIBED
Nexchio 40mg Capsule is safe to use in patients with kidney disease. No dose adjustment of Nexchio 40mg Capsule is recommended.
However, due to lack of data, exercised should be caution in patients with severe renal insufficiency.
Liver
CAUTION
Nexchio 40mg Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Nexchio 40mg Capsule may be needed. Please consult your doctor.
However, no dose adjustment is required for patients with mild to moderate liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Nexchio 40mg Capsule
₹8.9/Capsule
Prevzole Capsule
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₹4.75/capsule
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ESZ 40 Capsule
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₹4/capsule
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Some 40mg Capsule
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₹3.25/capsule
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Esocron 40 Capsule
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₹7.4/capsule
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Esomezole 40mg Capsule
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₹5.45/capsule
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Quick tips

  • It is a well-tolerated medicine and provides relief for a long time.
  • Some healthy tips to prevent acidity from happening:
    • Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
    • Avoid alcohol and smoking.
    • Avoid eating late at night or before bedtime.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Long-term use of Nexchio 40mg Capsule can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
  • Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.

Fact Box

Chemical Class
Sulfinylbenzimidazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Proton pump inhibitors

Patient concerns

arrow
Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers
Dr. Sunil Sekhri
Diabetology
You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed
Having problem of acid reflux disease with throat infection and pain in right side of abdomen
Dr. Aanchal Maheshwari
Ayurveda
take avipattikar churan 1 spoon twice before meal, for throat infection do gargles with lyuke warm water and mixing tankan bhasma a littlein it,,
arrow

FAQs

What is the best time to take Nexchio 40mg Capsule?

Usually, Nexchio 40mg Capsule is taken once a day, first thing in the morning. If you take Nexchio 40mg Capsule twice a day, take 1 dose in the morning and 1 dose in the evening. The tablets should be swallowed whole (remember not be chewed or crushed) and taken at least 1 hour before a meal with some water.

Can I take Nexchio 40mg Capsule with domperidone?

Yes, Nexchio 40mg Capsule can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone works by increasing the gut motility and Nexchio 40mg Capsule decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.

Can I take antacids along with Nexchio 40mg Capsule?

Yes, you can take antacids along with Nexchio 40mg Capsule. Take it 2 hours before or after you take Nexchio 40mg Capsule.

Can I take Nexchio 40mg Capsule for a long term?

Nexchio 40mg Capsule is usually prescribed for short term use only. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Nexchio 40mg Capsule may be prescribed for a long term duration as well. Long term use may carry an increased risk for side effects and must be discussed with the doctor. Please use Nexchio 40mg Capsule as advised by your doctor and under their supervision.

What are the long term side effects of Nexchio 40mg Capsule?

If Nexchio 40mg Capsule is used for more than 3 months, certain long term side effects may be seen. The most important of these is low magnesium levels in your blood which may make you feel tired, confused, dizzy, shaky or dizzy. You may also have muscle twitches or irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections and vitamin B12 deficiency. Vitamin B12 deficiency can make you anemic, as a result of which you may feel more tired, weak, or pale. Additionally you may have palpitations, shortness of breath, lightheadedness, indigestion, loss of appetite, flatulence (gas) or nerve problems such as numbness, tingling and problem in walking.

Can I stop taking Nexchio 40mg Capsule if I feel better?

If you have been taking Nexchio 40mg Capsule for a long time, stopping it abruptly may lead to increased acid production, thereby worsening your symptoms. Therefore, you must discuss any dose changes or if you wish to come off Nexchio 40mg Capsule.

Can Nexchio 40mg Capsule cause weight gain?

Weight gain is reported in less than 1% of the patients taking Nexchio 40mg Capsule but the exact cause is unknown. One possible explanation is higher food intake once the reflux symptoms are relieved. Lifestyle modifications such as proper diet and exercise can help to prevent weight gain.

Is Nexchio 40mg Capsule safe to use?

Yes, Nexchio 40mg Capsule is relatively safe to use. Most of the people who take Nexchio 40mg Capsule do not get a side effect. It is advised to be taken as directed by the doctor for maximum benefit.

Can I take Nexchio 40mg Capsule with ranitidine?

Yes, Nexchio 40mg Capsule can be taken with ranitidine. According to research reports, there are no significant interactions seen between Nexchio 40mg Capsule and ranitidine. However, you must take them together only if prescribed by the doctor.

Can I take alcohol with Nexchio 40mg Capsule?

No, alcohol intake is not advised with Nexchio 40mg Capsule. Alcohol itself does not affect the working of Nexchio 40mg Capsule, but it can increase the acid production. This may further cause worsening of your symptoms

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 24 Jan. 2019] (online) Available from:External Link
  2. Esomeprazole. Wilmington, DE: AstraZeneca Pharmaceuticals; 1989 [revised Dec. 2014]. [Accessed 28 Mar. 2019] (online) Available from:External Link
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Esomeprazole. [Updated 2019 Jun 3]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link
  5. Esomeprazole [Prescribing Information]. Haridwar, Uttarakhand: Pure & Cure Healthcare Pvt. Ltd.; 2023. [Accessed 22 Jun. 2023] (online) Available from:External Link
  6. Esomeprazole [Prescribing Information]. Haridwar, Uttarakhand: Pure & Cure Healthcare Pvt. Ltd.; 2023. [Accessed 22 Jun. 2023] (online) Available from:External Link

Marketer details

Name: Sachio Pharma Bangalore Private Limited
Address: 42/1, 303, Sree Durga 3rd Cross Mallesh Palaya KA 560075 IN
Country of origin: India

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