Nigrain Plus 40 mg/5 mg Tablet is a combination of two medicines that helps in preventing migraine. This medicine is not used for treatment of acute migraine attack.

Nigrain Plus 40 mg/5 mg Tablet is a combination of beta blocker- non selective and calcium channel blocker- migraine prevention

Uses of Nigrain Plus Tablet

Prevention of Migraine

Benefits of Nigrain Plus Tablet

In Prevention of Migraine

Nigrain Plus 40 mg/5 mg Tablet helps improve the flow of blood in your brain and prevents abnormal activity of muscles that triggers migraines. It is a very effective medicine for preventing migraine attacks, however, it does not treat an attack that has already started. By preventing and reducing the frequency migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.

Side effects of Nigrain Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nigrain Plus

Weight gain
Slow heart rate
Tiredness
Depression
Drowsiness
Abnormal dreams
Cold extremities

How to use Nigrain Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nigrain Plus 40 mg/5 mg Tablet is to be taken empty stomach.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Nigrain Plus 40 mg/5 mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Nigrain Plus 40 mg/5 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Nigrain Plus 40 mg/5 mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Nigrain Plus 40 mg/5 mg Tablet may cause side effects which could affect your ability to drive.
Nigrain Plus 40 mg/5 mg Tablet may cause visual disturbances, hallucinations, fatigue, mental confusion, dizziness or tiredness. This may affect your driving ability.

Kidney

SAFE IF PRESCRIBED

Nigrain Plus 40 mg/5 mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nigrain Plus 40 mg/5 mg Tablet may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

Nigrain Plus 40 mg/5 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Nigrain Plus 40 mg/5 mg Tablet may be needed. Please consult your doctor.
Regular monitoring of blood pressure is advisable for dose adjustment.

What if you forget to take Nigrain Plus Tablet?

If you miss a dose of Nigrain Plus 40 mg/5 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nigrain Plus 40 mg/5 mg Tablet

₹3.0/Tablet

Mighop LS 40mg/5mg Tablet

Anax Lifescience

₹3.2/tablet

7% costlier

Betabid Plus 40mg/5mg Tablet

Propel Healthcare

₹5.8/tablet

93% costlier

Cenopran-F 40mg/5mg Tablet

Inizia Healthcare Pvt Ltd

₹3.3/tablet

10% costlier

Razim 40mg/5mg Tablet

Jpee Healthcare

₹2.95/tablet

2% cheaper

Betakon Plus 40mg/5mg Tablet

Ikon Pharmachem Pvt Ltd

₹2.63/tablet

12% cheaper

View all substitutes

Quick tips

Nigrain Plus Tablet

You have been prescribed Nigrain Plus 40 mg/5 mg Tablet for prevention of migraine headaches.
Do not take it to treat an acute attack of migraine.
Some tips that may help avoid a migraine attack:
- Have your meals at the same time everyday
- Avoid bright lights and extreme temperatures
- Avoid loud music and noisy places
- Avoid chocolates, cheese, processed food, alcohol and smoking
- Get sufficient sleep and avoid stress
It should be taken at night-time before going to bed.
It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how Nigrain Plus 40 mg/5 mg Tablet affects you.
keep taking it regularly every day, even if you don't have any symptoms.

Fact Box

Habit Forming

Therapeutic Class

CARDIAC

Patient concerns

I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20)

Dr. Faran Siddiqui

Homeopathy

Migraine and headache are two different things migraine is primarily headache of one side in symmetrically

Some time at a sudden Strong half headache pain in left side and also left eye tearing Please consult me

Dr. Pushkar Mani

Physician

it could be migraine

User feedback

Patients taking Nigrain Plus 40 mg/5 mg Tablet

Once A Day

82%

Twice A Day

18%

What are you using Nigrain Plus Tablet for?

Migraine head*

100%

*Migraine headaches

FAQs

Nigrain Plus Tablet

In which conditions is the use of Nigrain Plus 40 mg/5 mg Tablet contraindicated?

Use of Nigrain Plus 40 mg/5 mg Tablet is considered to be harmful for patients with allergy to any of the ingredients or excipients of this medicine. This medicine contains propranolol, so its use should be avoided in patients with asthma, slow heart rate, abnormal heart rhythms, or heart conditions like AV block or sick sinus syndrome. Since this medicine also contains flunarizine, the use of this medicine should be avoided in patients with the history of depression or Parkinson's disease.

What are the instructions for the storage and disposal of Nigrain Plus 40 mg/5 mg Tablet?

Keep Nigrain Plus 40 mg/5 mg Tablet in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can I stop taking Nigrain Plus 40 mg/5 mg Tablet when my symptoms are improved?

Nigrain Plus 40 mg/5 mg Tablet is given as a prophylactic treatment for the prevention of migraine headaches. Do not stop taking this medicine until advised by your doctor as it may cause your migraine episodes to return. This medicine contains propranolol and a sudden withdrawal of propranolol may cause sweating, shaking, irregular or fast heartbeat, worsening of underlying angina or heart attack. You must take Nigrain Plus 40 mg/5 mg Tablet exactly as advised by your doctor.

Can Nigrain Plus 40 mg/5 mg Tablet be used for the treatment of a migraine headache?

No, Nigrain Plus 40 mg/5 mg Tablet does not help in relieving a migraine headache that has already started. It can only be used for preventing any new episode of migraine headaches.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Drugs.com. Flunarizine. [Accessed 25 Mar. 2019] (online) Available from:
Drugs.com. Propranolol Pregnancy and Breastfeeding Warnings. [Accessed 20 Mar. 2019] (online) Available from:
Flunarizine. High Wycombe, Buckinghamshire: Janssen Cilag Ltd.; 2009 [revised Feb. 2014]. [Accessed 11 Apr. 2019] (online) Available from:

Marketer details

Name: Torrent Pharmaceuticals Ltd

Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.