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Written By
DNB (Obstetrics and Gynecology), MS (Obstetrics and Gynecology)
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M.Pharm, B.Pharm
Last updated
21 Sep 2022 | 04:43 PM (IST)

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Open Plus Suspension


Your child’s medicine at a glance

Open Plus Suspension is given to children to treat the symptoms of acute diarrhea and dysentery caused due to bacterial infections. It kills the diarrhea-causing microorganism, restores the level of water and electrolytes, and reduces the symptoms, severity, and duration of illness.

Give Open Plus Suspension to your child orally either before or after food. For best results, you must also keep giving ORS (oral rehydration solution) throughout the day. Usually, Open Plus Suspension is prescribed two times a day, once in the morning and once at bedtime. However, this dose may vary depending upon your child’s symptoms, body weight, and age. So, adhere to the dose, time, and way prescribed by the doctor. Repeat the dose if your child vomits within 30 minutes of the intake of Open Plus Suspension. However, do not double the dose if it is already time for the next dose.

Some children may develop minor and short-term side effects after the intake of this medicine. These include nausea, vomiting, stomach pain, headache, skin rash, and itching. These episodes are temporary and subside on their own. However, in case they persist for long or start bothering your child, you must consult your child’s doctor without any delay.

Do inform your child’s doctor if your child has ever had any previous episode of allergy, bowel obstruction, electrolyte imbalance, heart problem, liver impairment, and kidney malfunction. This will guide the doctor in planning your child’s overall treatment.

Uses of Open Plus Suspension in children

Benefits of Open Plus Suspension for your child

In Treatment of Diarrhea

Diarrhea refers to the passing of loose, watery stools three or more times a day. It usually happens due to an infection in the gastrointestinal tract. Open Plus Suspension reduces the excessive secretion of water and electrolytes and helps replenish the lost fluids and salts. It also helps treat loose stools and prevents abdominal distension or flatulence. Encourage your child to drink plenty of fluids while taking it to stay hydrated. Your child may start to feel better after getting treated for a few days to a week. However, do not extend the course or stop the medicine by yourself without consulting your child’s doctor. This may lead to the recurrence of symptoms.

In Treatment of Dysentery

Dysentery or amoebic dysentery is a parasitic infection of the intestines that occurs mostly due to intake of contaminated food or water. The symptoms include loose stools (diarrhea), stomach cramps, and stomach pain. Open Plus Suspension helps to treat this infection by killing the infection causing parasites. It relieves these symptoms and also helps to prevent them from coming back.

Side effects of Open Plus Suspension in children

Open Plus Suspension does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Open Plus

  • Nausea
  • Vomiting
  • Stomach pain
  • Skin rash
  • Itching

How can I give Open Plus Suspension to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Open Plus Suspension is to be taken with food.

How Open Plus Suspension works

Open Plus Suspension contains three medicines Ofloxacin, Ornidazole, and Racecadotril. Together, these ingredients prove effective against diarrhea and dysentery. Racecadotril is an enkephalinase inhibitor that has anti-secretory effects. Simply put, this particular active ingredient reduces the secretion of water and electrolytes from the intestine. This helps reduce the amount of fluid lost from the body in diarrhea. Ofloxacin is an antibiotic. It kills bacteria by preventing them from reproducing and causing infection. Ornidazole is also an antibiotic that kills other microorganisms in addition to bacteria by damaging their DNA.

Safety advice

Kidney
CAUTION
Open Plus Suspension should be used with caution in patients with kidney disease. Dose adjustment of Open Plus Suspension may be needed. Please consult your doctor.
Liver
CAUTION
Open Plus Suspension should be used with caution in patients with liver disease. Dose adjustment of Open Plus Suspension may be needed. Please consult your doctor.

What if I forget to give Open Plus Suspension to my child?

Do not panic. You can give the missed dose medicine as soon as you remember unless your child’s doctor has advised otherwise. Remember not to double the dose to catch up with the missed one. In case of any confusion, do consult your child’s doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Open Plus Suspension
₹42.5/Suspension
Actoflox Forte Suspension
Fitwel Pharmaceuticals Private Limited
₹89/suspension
5% costlier
Ontaflox Forte Suspension
Fitwel Pharmaceuticals Private Limited
₹89/suspension
5% costlier
Axioff OZR Suspension
Axis Life Science Pvt Ltd
₹55/suspension
35% cheaper
Ofter Plus Suspension
Axter Pharmaceuticals Pvt Ltd
₹70/suspension
18% cheaper

Quick tips

  • Open Plus Suspension should be used together with an oral rehydration solution (ORS) to provide adequate fluid and electrolyte replacement.
  • Give your child plenty of fluids to replenish water and mineral loss.
  • Open Plus Suspension may cause an altered taste. Eating citrus fruit or sipping plenty of water or fruit juice may help.
  • Do not mix Open Plus Suspension along with any other herbal or ayurvedic medicine as it can harm.
  • Do not give Open Plus Suspension if your child has persistent uncontrolled vomiting as this medicine will not be absorbed.

Fact Box

Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL

Patient concerns

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My whole back is full of boils. Pic attached. Please suggest treatment., .
Dr. Sanjay Bhatt
Physician
Not able to open pic
Sir,i have got problem in my stomach,i have to go to letrine 4-5 times in a day.as it is not probkem of diarrhea because letrine is not coming in liquid form.Pain is not so much in stomach but sometimes got pain for 5-10 minutes in a day and after taking food, 30-45 min later i have to go to letrine.This problem is continued around 10 days.today i met by a physician he gave me one capsule:Rabonid-DSR and one tablet:Oraflox-OZ for 5 days .Please give me right suggestion and medicine also. and one thing sir,how to take a capsule (take complete or take material inside the capsule) is remove the cylindrical cover of capsule or not?? thnksss sir
Dr. Pushkar Mani
Physician
Just take capsule as it comesOpen the rapper and take
arrow

FAQs

What if I give too much Open Plus Suspension by mistake?

Though an extra dose of Open Plus Suspension is unlikely to harm, you must immediately speak to the doctor. The reason being, overdose may cause unwanted side effects such as seizures, tremors, severe headache, sudden weakness, unconsciousness, and palpitations (irregularities of heartbeat). In case you notice any of these side effects, rush to your child’s doctor on an immediate basis.

My child is one year old and is suffering from a neurological disorder. Is it safe to give Open Plus Suspension?

Usually, Open Plus Suspension does not enter into the central nervous system and lacks the potential to cause serious side effects such as neurotoxicity. However, if given to children aged less than 2 years of age, it may enter the brain as they have underdeveloped membranes. Consult your child’s doctor before giving Open Plus Suspension in such a condition.

Can other medicines be given at the same time as Open Plus Suspension?

Open Plus Suspension can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Open Plus Suspension. Also, check with your child’s doctor before giving any medicine to your child.

My child is suffering from long-term (chronic) diarrhea. Can I give Open Plus Suspension?

The use of Open Plus Suspension in chronic diarrhea has not been sufficiently studied. Therefore, it is best to consult your child’s doctor before giving any medicine to your child.

Can I get my child vaccinated while on treatment with Open Plus Suspension?

Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. U.S. Food and Drug Administration. How to Treat Diarrhea in Infants and Young Children. 2011. [Accessed 20 Jan. 2021] (online) Available from:External Link
  2. Racecadotril [Product Information Leaflet]. Paris, France: Bioprojet Pharma; 2013. [Accessed 20 Jan. 2021] (online) Available from:External Link
  3. Proposal for the inclusion of racecadotril in the WHO model list of essential medicines. Paris, France; 2007. [Accessed 20 Jan. 2021] (online) Available from:External Link
  4. Ofloxacin [FDA Label]. Raritan, NJ: Ortho-McNeil-Janssen Pharmaceuticals, Inc.; 2008. [Accessed 20 Jan. 2021] (online) Available from:External Link
  5. Pediatric Oncall, Child Health Care. Ornidazole. [Accessed 20 Jan. 2021] (online) Available from:External Link
Country of origin: India

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