Author Details
Written By
BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
24 Nov 2020 | 03:27 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

P Mide 750mg Tablet

Prescription Required

Product introduction

P Mide 750mg Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.

P Mide 750mg Tablet is given in combination with at least one other tuberculosis medicine. It acts by killing the causative bacteria. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at a fixed time every day to avoid a missed dose. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Please let your doctor know about any changes in your weight as the dose of this medicine depends on the overall body weight of a person. Any changes in weight might need dose modification.

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.

Inform your doctor if you notice signs of jaundice i.e. yellowing of eyes or skin, dark urine, stomach pain or joint pain. You may also develop hepatitis (viral infection of the liver), increased liver enzymes and joint pain as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and might need dose modification.

Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of P Mide Tablet

Benefits of P Mide Tablet

In Tuberculosis (TB)

P Mide 750mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of P Mide Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of P Mide

  • Jaundice
  • Hepatitis (viral infection of liver)
  • Increased liver enzymes
  • Joint pain

How to use P Mide Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. P Mide 750mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How P Mide Tablet works

P Mide 750mg Tablet is an antitubercular medicine. In the body, it gets converted to pyrazinoic acid. This pyrazinoic acid inhibits fatty acid synthase I (bacterial enzyme), which is essential for bacterial growth. Thus, it works as a bacteriocidal to prohibit their growth and treats tuberculosis.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with P Mide 750mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
P Mide 750mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
P Mide 750mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether P Mide 750mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
P Mide 750mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of P Mide 750mg Tablet may be needed. Please consult your doctor.
Kidney function tests are advised before you start taking this medicine.
Liver
CAUTION
P Mide 750mg Tablet should be used with caution in patients with liver disease. Dose adjustment of P Mide 750mg Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advised before and after the start of the treatment.

What if you forget to take P Mide Tablet?

If you miss a dose of P Mide 750mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
P Mide 750mg Tablet
₹3.8/Tablet
₹3.38/tablet
11% cheaper
P Zide 750 Tablet
Cadila Pharmaceuticals Ltd
₹3.39/tablet
11% cheaper
Pza Ciba 750mg Tablet
Novartis India Ltd
₹3.3/tablet
13% cheaper
Macrozide 750 Tablet
Macleods Pharmaceuticals Pvt Ltd
₹3.91/tablet
3% costlier
Pizamax 750mg Tablet
Ind Swift Laboratories Ltd
₹0.77/tablet
80% cheaper

Quick tips

  • P Mide 750mg Tablet along with other medications effectively treats tuberculosis.
  • Do not to forget a dose, as this increases the risk of the bacteria becoming resistant to the medicine, and also increases the risk of getting side effects.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Avoid drinking alcohol while taking P Mide 750mg Tablet as this may increase the risk of side effects on the liver.
  • Use a reliable contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking P Mide 750mg Tablet as it may make hormonal contraceptives such as the pill less effective.

Fact Box

Chemical Class
Nicotinic acid derivatives
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Mycobacterial fatty acid synthase

Patient concerns

arrow
Can we have zerodol p tablet regularly?
Dr. Sunil Sekhri
Diabetology
What are your symptoms
My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
arrow

FAQs

What is P Mide 750mg Tablet and what is it used for?

P Mide 750mg Tablet is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis

Is P Mide 750mg Tablet bactericidal?

P Mide 750mg Tablet is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases

How does P Mide 750mg Tablet work/treat tuberculosis?

P Mide 750mg Tablet kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for P Mide 750mg Tablet is not known

How does P Mide 750mg Tablet cause hyperuricemia and gout?

Following oral intake of P Mide 750mg Tablet, it gets converted in the body to pyrazinoic acid (active chemical form of P Mide 750mg Tablet). Pyrazinoic acid blocks the excretion of urates (salt form of uric acid) by the kidneys. This causes an increase in blood levels of uric acid (hyperuricemia). Excess uric acid accumulation between joints causes pain, swelling, redness and stiffness in joints (gout).

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1554-555.
  2. Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 827.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1171-72.
  4. Drugs.com. Pyrazinamide. [Accessed 31 Mar. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198 [Accessed 29 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:External Link
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.