Primegard 500 mg/2000 mg Injection is a combination of two antibiotics prescribed to treat various types of bacterial infections. It fights against the infection by inhibiting the growth of the microorganisms to prevent further infections.

Primegard 500 mg/2000 mg Injection is generally administered by a nurse or doctor; do not self-administer this medicine at home. Do not miss any scheduled appointments for receiving this injection. The course of the medicine should be completed even if you feel better.

Common side effects of this medicine include mild injection site reactions, such as redness, swelling, and pain; ringing in the ear; hearing loss; vertigo; nausea; and vomiting. To overcome any such side effects, eat a balanced diet and drink plenty of fluid. If any of the side effects get worse or you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), consult your doctor immediately.

Do not receive this injection if you have a known history of allergy to this medicine. Before taking this medicine, tell your doctor if you have any problems with your liver or kidneys. Pregnant or breastfeeding women should also consult with their doctors before receiving the injection.

Uses of Primegard Injection

Treatment of Bacterial infections

Benefits of Primegard Injection

In Treatment of Bacterial infections

Primegard 500 mg/2000 mg Injection kills the bacteria that can cause serious infections. It usually makes you feel better very quickly, but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and you do not become resistant.

Side effects of Primegard Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Primegard

Diarrhea
Nausea
Injection site phlebitis
Myoclonic encephalopathy
Seizure
Cochlear damage
Balance disorder (loss of balance)
Injection site reaction
Muscle paralysis
Apnea (absence of breathing)
Stevens-Johnson syndrome
Erythema multiforme
Toxic epidermal necrolysis
Renal dysfunction
Increased creatinine level in blood
Albumin in urine
Low urine output
Nephropathy toxicity
Aplastic anemia
Hemolytic anemia
Hemorrhage
Cholestasis
Decreased blood cells (red cells, white cells, and platelets)
Injection site reactions (pain, swelling, redness)
Hearing loss
Vomiting

How to use Primegard Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Primegard Injection works

Primegard 500 mg/2000 mg Injection is a combination of two medicines: amikacin and cefepime. Amikacin is an antibiotic which stops bacterial growth by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Cefepime is also an antibiotic that works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Together, these medications eradicate the bacterial infection effectively.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Primegard 500 mg/2000 mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Primegard 500 mg/2000 mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Primegard 500 mg/2000 mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Avoid prolonged use of Primegard 500 mg/2000 mg Injection, since it may have possible effects such as rash and diarrhea.

Driving

UNSAFE

Primegard 500 mg/2000 mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Primegard 500 mg/2000 mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Primegard 500 mg/2000 mg Injection may be needed. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Primegard 500 mg/2000 mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Primegard 500 mg/2000 mg Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Primegard Injection?

If you miss a dose of Primegard 500 mg/2000 mg Injection , please consult your doctor

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Primegard 500 mg/2000 mg Injection

₹200/Injection

Potentox 500 mg/2000 mg Injection

Venus Remedies Ltd

₹673/injection

68% costlier

CA 007 500 mg/2000 mg Injection

Themis Medicare Ltd

₹400/injection

same price

Quick tips

Primegard 500 mg/2000 mg Injection is given as an injection into vein or drip under the supervision of a doctor.
Do not skip any doses and finish the full course of the treatment even if you feel better. Stopping it early may cause recurrence of the infection and make it harder to treat.
Your doctor will monitor your kidney function, blood urea level, and hearing capability regularly during the treatment.
During the treatment with this combination medicine, take proper rest to achieve a faster recovery.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Patient concerns

I have a history of recurring yeast and bacterial vaginosis infections.

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days

My child verry high cough and fever in cold sesion try to much doctor but result is no . It's will be countiue cough and fever it's good to be only antiboitic

Dr. Gopal Samdani

Paediatrics

Antibiotics are required if bacterial infections. Consult child specialist

What if I don't get better after using Primegard 500 mg/2000 mg Injection?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

How long does Primegard 500 mg/2000 mg Injection takes to work?

Usually, Primegard 500 mg/2000 mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

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Peripheral Smear Examination

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Venus Remedies Limited. Amikacin + Cefepime. [Accessed 08 Apr. 2019] (online) Available from:
Amikacin sulfate. Hurley, Maidenhead: Hospira UK Limited; 1996 [revised Aug. 2015]. [Accessed 08 Apr. 2019] (online) Available from:
Cefepime. Deerfield, Illinois: Baxter Healthcare Corporation; 1996. [Accessed 08 Apr. 2019] (online) Available from:
Amikacin [Patient Information Sheet]. Port Elizabeth, South Africa: Fresenius Kabi Manufacturing SA (Pty) Ltd.; 2012. [Accessed 10 Oct. 2023] (online) Available from:
Cefepime [Prescribing Information]. Bethlehem, PA: Piramal Critical Care; 2019. [Accessed 08 Apr. 2023] (online) Available from:

Marketer details

Name: Ipca Laboratories Ltd

Address: 142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra

Country of origin: India

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