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PhD (Pharmacology), PGDPRA
Reviewed By
MD Pharmacology, MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Rifater 120 mg/80 mg/250 mg Tablet


Introduction of Rifater Tablet

Rifater 120 mg/80 mg/250 mg Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.

Rifater 120 mg/80 mg/250 mg Tablet is a combination of isoniazid, pyrazinamide, and rifampicin.

Uses of Rifater Tablet

Benefits of Rifater Tablet

In Tuberculosis (TB)

Rifater 120 mg/80 mg/250 mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Rifater Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Rifater

  • Nausea
  • Vomiting
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Abdominal pain
  • Skin rash
  • Hepatitis (viral infection of liver)
  • Lethargy
  • Low blood platelets
  • Thrombocytopenic purpura
  • Cutaneous reactions

How to use Rifater Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rifater 120 mg/80 mg/250 mg Tablet is to be taken empty stomach.
Avoid Rifater 120 mg/80 mg/250 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking Rifater 120 mg/80 mg/250 mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Rifater 120 mg/80 mg/250 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Rifater 120 mg/80 mg/250 mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Rifater 120 mg/80 mg/250 mg Tablet may cause side effects which could affect your ability to drive.
You may feel dizzy or faint, have problems with vision or have other side effects that could affect your ability to drive.
Kidney
CAUTION
Rifater 120 mg/80 mg/250 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Rifater 120 mg/80 mg/250 mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Rifater 120 mg/80 mg/250 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Rifater 120 mg/80 mg/250 mg Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advised before and after the start of the treatment.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Rifater 120 mg/80 mg/250 mg Tablet
₹0.91/Tablet
Rip 120 mg/80 mg/250 mg Tablet
Sunij Pharma Pvt Ltd
₹0.89/tablet
2% cheaper

Quick tips

Rifater Tablet

  • Rifater 120 mg/80 mg/250 mg Tablet should be taken on an empty stomach but at the same time every day.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Rifater 120 mg/80 mg/250 mg Tablet affects you.
  • Avoid drinking alcohol while taking this medicine as this may increase the risk of side effects on the liver.
  • Avoid taking hormone-based birth control methods as Rifater 120 mg/80 mg/250 mg Tablet may decrease their effectiveness.
  • Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI INFECTIVES

Patient concerns

Patient concerns

arrow
My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
Though took vaccines in childhood, the test for TB came positive. Was advised to undergo treatment.physically absolute fit and healthy, is it advisable to take treatment?
Dr. Anshum Aneja Arora
Pulmonology
If sputum is positive for Tb , treatment is absolutely essential. Read more at www.arohealth.com/tuberculosis
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 09 Apr. 2019] (online) Available from:External Link
  2. Drugs.com. Pyrazinamide. [Accessed 09 Apr. 2019] (online) Available from:External Link
  3. Drugs.com. Rifampicin. [Accessed 09 Apr. 2019] (online) Available from:External Link

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Country of origin: India

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