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Product introduction

S-One Trio Capsule is a combination medicine used in the treatment of stomach cancer. It can be used alone or in combination with some medicines as part of combination chemotherapy. It works by interfering with the growth of cancer cells, which are eventually destroyed.

S-One Trio Capsule should be taken with water at least 1 hour before or 1 hour after a meal. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include bone marrow suppression, acute renal failure, diarrhea, dehydration, electrolyte disturbance, and lacrimal disorders. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, inform your doctor if you have medical conditions involving blood, kidney, and liver or if you are suffering from any breathing disorder.  This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of S-One Trio Capsule

Benefits of S-One Trio Capsule

In Treatment of Stomach cancer

Stomach cancer also known as gastric cancer, may occur in the inner lining (called mucosa) of the stomach or in the walls of the stomach. These are of various kinds depending on the origin, affected area and severity of the cancer. S-One Trio Capsule helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit.

Side effects of S-One Trio Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of S-One Trio

  • Bone marrow suppression
  • Acute renal failure
  • Diarrhea
  • Dehydration
  • Electrolyte imbalance
  • Lacrimation (flow of tears)

How to use S-One Trio Capsule

Take this medicine in the dose and duration as advised by your doctor. S-One Trio Capsule is to be taken empty stomach.

How S-One Trio Capsule works

S-One Trio Capsule is a combination of anticancer medications. Tegafur gets converted to its active form known as 5-fluorouracil (5-FU) that inhibits the synthesis and function of genetic material DNA and RNA and prevents the growth of cancer cells. Gimeracil prevents the breakdown of 5-FU, which helps maintain high concentrations of 5-FU against cancer cells. Oteracil suppresses 5-FU’s gastrointestinal toxicity.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with S-One Trio Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
S-One Trio Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
S-One Trio Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
S-One Trio Capsule may cause side effects which could affect your ability to drive.
S-One Trio Capsule can cause fatigue, dizziness, blurred vision, and nausea when used in combination with cisplatin.
Kidney
CAUTION
S-One Trio Capsule should be used with caution in patients with kidney disease. Dose adjustment of S-One Trio Capsule may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
S-One Trio Capsule is safe to use in patients with liver disease. No dose adjustment of S-One Trio Capsule is recommended.

What if you forget to take S-One Trio Capsule?

If you miss a dose of S-One Trio Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
S-One Trio Capsule
₹425.0/Capsule
Tegoyes 5.8mg/15.8mg/20mg Capsule
Torrent Pharmaceuticals Ltd
₹473.14/capsule
11% costlier
₹437.71/capsule
3% costlier
Furmecil Capsule
BDR Pharmaceuticals Internationals Pvt
₹428.14/capsule
1% costlier

Quick tips

  • You may be at risk of infection, so try to avoid crowds or people with colds, gargle upon returning home, and wash your hands before meals and before and after using the bathroom.
  • To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals. If you vomit a dose of medication, make sure you tell your doctor. Do not replace the dose that has been vomited.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists. If you experience diarrhea, avoid high-fiber, fatty, and spicy foods.
  • To prevent bleeding, avoid hard work or strenuous sports to prevent injuries and bruises.
  • Decreased sensation, numbness, and tingling in fingers and toes may worsen with repeated doses of S-One Trio Capsule. It is important to report this to your doctor.

Fact Box

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Therapeutic Class
ANTI NEOPLASTICS

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FAQs

What is S-One Trio Capsule used for?

S-One Trio Capsule is used in adults for the treatment of stomach cancer when given in combination with another medication named cisplatin.

Can S-One Trio Capsule be used during pregnancy?

No, this medicine should not be used during pregnancy as it can harm the unborn child. Avoid getting pregnant and use an effective method of birth control during your treatment and for at least 6 months after the last dose of S-One Trio Capsule.

Can S-One Trio Capsule affect my fertility?

There are no data available on the effect of this medicine in combination with cisplatin. In case of any doubts, it is always better to talk to your doctor if you have concerns about fertility.

Does S-One Trio Capsule cause hair loss?

Yes, while taking this medicine, your hair may become brittle and break. You may also experience patchy hair loss or thinning. These conditions tend to resolve once treatment is stopped. Be gentle when brushing and washing hair to manage hair loss.

How will you know that S-One Trio Capsule is working?

Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.

I have noticed some changes in my skin after taking S-One Trio Capsule? What should I do?

Use a moisturizer to get relief from rashes, dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen (SPF of more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water baths and wear loose and cotton fabric clothes. Your skin will become better once treatment is stopped.

How to relieve constipation during treatment with S-One Trio Capsule?

To relieve constipation, include fiber in your diet (fruits and vegetables), drink 8-10 glasses of fluids a day, and keep active. A stool softener (with a doctor's prescription) once or twice a day may prevent constipation. If you do not have a bowel movement for 2-3 days, consult your doctor.

I am noticing a change in my taste. How shall I improve my taste?

You may experience a metallic taste or find that food has no taste at all. You may dislike foods or beverages that you liked before receiving cancer treatment. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You can also add extra flavor or seasonings to your food.

Are there any precautions for tingling sensation and numbness in my arms and legs?

This medicine causes tingling, numbness, pain, or burning sensation in the arms or legs. Be careful when moving around, as the numbness may make it harder to walk, feel your hands or feet, or increase your risk of falls. Talk to your doctor if you feel these symptoms. You may need to change your dosage or schedule.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Tegafur, Gimeracil and Oteracil Capsules [Package Insert]. Torrent Pharmaceuticals Ltd.; 2022. [Accessed 24 Nov. 2022] (online) Available from: External Link

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver S-One Trio Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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