Sazomic 500 Tablet is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease).

Sazomic 500 Tablet is to be taken with food. This will help you prevent an upset stomach. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better. Taking it with plenty of water can help you avoid kidney problems such as kidney stones.

Using this medicine may cause some common side effects such as nausea, headache, loss of appetite, vomiting, diarrhea, weight loss, and gastrointestinal discomfort. You should consult with your doctor if any of these side effects do resolve with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problem with your heart, kidneys, or liver. Also, tell your doctor about all the other medicines you are taking. Your doctor may recommend regular blood tests to check your kidney and liver functions, and blood components. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses of Sazomic Tablet

Benefits of Sazomic Tablet

In Treatment of Rheumatoid arthritis

Sazomic 500 Tablet helps treat inflammation, pain and swelling in rheumatoid arthritis by decreasing the immune system response of the patient. It is given in the dose and frequency that suits your condition. This will be decided by the doctor. You must follow your doctor’s instructions carefully and let your doctor know if you have any bothersome side effects after taking this medicine.

In Treatment of Ulcerative colitis

Ulcerative colitis is a disease of the large intestine (colon) and rectum in which the lining of the bowel becomes red and swollen. This can lead to bleeding, frequent diarrhea and abdominal pain. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You should drink plenty of fluids while taking on treatment with this medicine to make sure you stay hydrated.

In Treatment of Crohn’s disease

Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines. The most common symptoms are diarrhea and pain in your abdomen. Sazomic 500 Tablet helps reduce the inflammation, relieve the symptoms, and prevent them from coming back.

In Treatment of Ankylosing spondylitis

Ankylosing spondylitis is a rare type of arthritis that affects the spine or larger joints. It usually starts in your lower back and can spread up to your neck or damage joints in other parts of your body. Sazomic 500 Tablet helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

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Side effects of Sazomic Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sazomic

Diarrhea
Gastrointestinal discomfort
Headache
Loss of appetite
Nausea
Oligospermia (low sperm count)
Vomiting
Weight loss

How to use Sazomic Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sazomic 500 Tablet is to be taken with food.

How Sazomic Tablet works

Sazomic 500 Tablet is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases and blocks the chemical messengers that cause inflammation (swelling).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Sazomic 500 Tablet.

Pregnancy

SAFE IF PRESCRIBED

Sazomic 500 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Sazomic 500 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Sazomic 500 Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Sazomic 500 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Sazomic 500 Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advisable while you are taking this medicine.

Liver

UNSAFE

Sazomic 500 Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Sazomic Tablet?

If you miss a dose of Sazomic 500 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Sazomic 500 Tablet

₹2.9/Tablet

Sazo EN 500mg Tablet

₹4.4/tablet

52% costlier

Iwata 500mg Tablet

₹2.87/tablet

1% cheaper

Colizine 500mg Tablet

₹2.75/tablet

5% cheaper

Sazowin 500mg Tablet

Innovative Pharmaceuticals

₹7.2/tablet

148% costlier

Sulfunol 500mg Tablet

Knoll Pharmaceuticals Ltd

₹4.37/tablet

51% costlier

View all substitutes

Quick tips

Take it with food to avoid an upset stomach.
It may take 6-8 weeks for Sazomic 500 Tablet to work. Keep taking it as prescribed.
Drink plenty of fluids while taking Sazomic 500 Tablet in order to avoid kidney problems such as kidney stones.
It may cause a deficiency of folic acid. Take the supplements as suggested by the doctor.
Do not take Sazomic 500 Tablet if you are allergic to sulfa drugs or aspirin.
It may discolour your skin, urine, saliva and tears an orange/yellow colour. This is normal and not harmful.
Regular blood tests to monitor your liver function, kidney function, and the levels of your blood components are required while taking this medicine.
Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class

Aminosalicylic Acids Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics

Patient concerns

Suffering from ultratics colitis i have done colonoscopy test 04 months back From 05 months how many months I have to take medicines is it cure completely

Dr. Kunal Parasar

Surgical Gastroenterology

Ulcerative colitis is a lifelong disease with remission and exacerbations. Durations of remission cant b predicted all d time

Hi, I was diagnosed for Ulcerative Colitis in 2009. I was administered with Mesacol , I was back to normal. In past 1 month , after having food lunch or dinner I feel uneasy such as indigestion, having to force for motions next day. Sometimes Iam unable to pass motions. I feel tired also. Pls suggest.

Dr. Kunal Parasar

Surgical Gastroenterology

Ulcerative colitis is a lifong disease q with remission and exacerbation . U should b under constant follow up of ur gastroenterologist

Suffering from severe lower back pain since 6 years. As per MRI it is lumbar spondylosis,but Doctor told that it is one of the types of arthritis in which bridge is getting formed on spine Is there any permanent solution .at present taking Sazo 500 twice a day

Dr. Akshat Goel

Orthopaedics

It's called Ankylosing spondylitis". no permanent cure for this All you need to do is to exercise each and every joint of your body regularly "Along with the medication

FAQs

Is Sazomic 500 Tablet a steroid or a painkiller?

Sazomic 500 Tablet is neither a steroid nor a painkiller. It is an anti-inflammatory medicine. It is used to treat and manage ulcerative colitis and Crohn's disease in which the intestines become inflamed (swelling of intestines). It is also used to treat rheumatoid arthritis (painful joint disease).

What is Sazomic 500 Tablet and what is it used for?

Sazomic 500 Tablet belongs to a group of medicines called aminosalicylates. It is an anti-inflammatory disease and is used to treat bowel inflammation, diarrhea (stool frequency), rectal bleeding, and abdominal pain in patients with ulcerative colitis and Crohn’s disease. In rheumatoid arthritis, it helps prevent damage to the joints and works slowly to reduce swelling and stiffness in your joints.

I have been prescribed Sazomic 500 Tablet for rheumatoid arthritis. When can I expect the pain in joints to be better?

Sazomic 500 Tablet does not work right away. It takes about 6 to 12 weeks to deliver the full effect.You may start feeling better in 4 weeks after starting Sazomic 500 Tablet, but it can vary from person to person and some of the patients may notice improvement after 3 months. Consumption of medicine should not be stopped without consulting your doctor.

For how long do I need to take Sazomic 500 Tablet?

If you are able to tolerate Sazomic 500 Tablet which means the side effects do not bother you, then you have to continue Sazomic 500 Tablet till the disease remains in remission. It is better to take Sazomic 500 Tablet for the prescribed period.

Does the use of Sazomic 500 Tablet for the treatment of arthritis affect the kidney function?

Though it is uncommon, Sazomic 500 Tablet may affect your kidney function. Therefore, it is important that your kidney function remains normal before you start taking Sazomic 500 Tablet. If during treatment with Sazomic 500 Tablet your kidney functions become abnormal, you should consult your doctor.

Do I need to get any blood tests done while on Sazomic 500 Tablet therapy?

Your doctor will advise you blood tests to check your blood cell counts and your kidney function before starting your treatment and regularly during treatment. The tests should also be done to measure substances produced by your liver known as enzymes (liver function tests) and urine for protein and blood before you start treatment and at regular intervals.

Can Sazomic 500 Tablet affect my fertility?

Decreased sperm count and infertility have been reported in some males. These may disappear once Sazomic 500 Tablet is discontinued.

Can I take azathioprine along with Sazomic 500 Tablet?

You should avoid using Sazomic 500 Tablet with azathioprine since there are chances of decrease in blood cell count, which can be a serious side effect.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 632-33.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1295-97.
Sulfasalazine. Sandwich, Kent: Pfizer Limited; 2010 [revised Feb. 2014]. [Accessed 23 Jan. 2019] (online) Avaialble from:
Sulfasalazine. Uppsala, Sweden: Recipharm, Uppsala; 2018. [Accessed 18 Jun. 2019] (online) Available from:
Sulfasalazine. New York, New York: Pharmacia & Upjohn Co.; 2014. [Accessed 18 Jun. 2019] (online) Available from:
Oxford Radcliffe Hospitals: NHS Trust. Sulfasalazine. [Accessed 18 Jun. 2018] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
Drugs.com. Sulfasalazine Pregnancy and Breastfeeding Warnings. [Accessed 02 Apr. 2019] (online) Available from:

Country of origin: India

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