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MD (Pharmacology), MBBS
Last updated
17 Aug 2023 | 12:58 PM (IST)

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Stresnil 0.5 Tablet


Product introduction

Stresnil 0.5 Tablet is used to treat insomnia. It helps to calm the brain by decreasing the abnormal and excessive activity of the nerve cells. It also regulates the sleep cycle and helps the patient to fall asleep quickly.

Stresnil 0.5 Tablet should be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has high habit-forming potential. However, take it as advised by your doctor because it is not recommended for long-term use. Inform your doctor if you are suffering from any liver or kidney problems before taking this medicine. You should avoid smoking and alcohol while using this medicine. Regular monitoring of blood sugar levels is required while taking this medicine.

Some common side effects of this medicine include confusion, tiredness, and memory impairment. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. It may cause weight gain or weight loss depending upon person to person. To prevent weight gain, you can eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. However, weight loss can be managed by consulting a dietitian who can help you in increasing your food portions.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Stresnil Tablet

Benefits of Stresnil Tablet

In Treatment of Insomnia

Stresnil 0.5 Tablet is a combination of two medicines that helps treat insomnia (difficulty falling or staying asleep) in people who have problems related to their sleeping habits. Insomnia may cause you to wake up earlier than usual and you may find it difficult to go back to sleep. It works by slowing down the abnormal activity of nerves in the brain to allow sleep. It also improves the sleep-wake cycle and restores it to normal. This helps you relax, feel calm, and more energetic. It also helps you concentrate better and improves your quality of life.

Side effects of Stresnil Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Stresnil

  • Confusion
  • Drowsiness
  • Tiredness
  • Uncoordinated body movements
  • Depression
  • Memory impairment

How to use Stresnil Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Stresnil 0.5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Stresnil Tablet works

Stresnil 0.5 Tablet is a combination of two medicines: Alprazolam and melatonin, which helps you sleep. Alprazolam is a benzodiazepine. It works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain and induces sleep. Melatonin is a natural hormone which helps to regulate the sleep-wake cycle.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Stresnil 0.5 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Stresnil 0.5 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Stresnil 0.5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Stresnil 0.5 Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Stresnil 0.5 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Stresnil 0.5 Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Stresnil 0.5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Stresnil 0.5 Tablet may be needed. Please consult your doctor.
There is very limited experience on use of Stresnil 0.5 Tablet in patients with underlying liver disease.

What if you forget to take Stresnil Tablet?

If you miss a dose of Stresnil 0.5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Stresnil 0.5 Tablet
₹1.9/Tablet
Alprax Z 0.5 mg/3 mg Tablet
Torrent Pharmaceuticals Ltd
₹2.27/tablet
19% costlier
Bioclock 0.5mg/3mg Tablet
Valiant Healthcare Limited
₹0.95/tablet
50% cheaper
Zam MT 0.5mg/3mg Tablet
East West Pharma
₹1.55/tablet
18% cheaper

Quick tips

  • Stresnil 0.5 Tablet is prescribed for the treatment of insomnia.
  • It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
  • Do not stop taking Stresnil 0.5 Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • Inform your doctor if you have liver disease.
  • Inform your doctor if you are pregnant or breastfeeding.
  • Stresnil 0.5 Tablet is prescribed for the treatment of insomnia.
  • It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
  • Do not stop taking Stresnil 0.5 Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • Inform your doctor if you have liver disease.
  • Inform your doctor if you are pregnant or breastfeeding.

Fact Box

Habit Forming
Yes
Therapeutic Class
NEURO CNS

Patient concerns

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Suffering from insomnia Regularly taking stresnil 0.5 and clonil 0.5 Otherwise falling asleep.
Dr. Jyoti Kapoor Madan
Psychiatry
Sleep problems are often caused by underlying physical and/ or psychological cause. This requires examination of the patient so that proper treatment can be initiated. Often stress/ anxiety/ depression or mood disorder needs to be dealt with and sleeping pills are not adequate treatment. Please go through the link below - http://drjyotikapoor.com/2015/01/26/sleep-disorders/
Good evening sir, I am suffering from OCD and depression for the last 30 year and taking physiciatric medicine including nitrosun 5 mg and stresnil 0.5 mg 1 tab each every night after dinner but lately I have developed irritation anger and abusive language please suggest some remedy . I am taking following medicine dicorarate er 500 , sizodone 2 mg, nitrosun 5 mg and stresnil 0.5 mg apart from diabetes and hyper tension med and diabetic neuropathy med. Please suggest .
Dr. Jyoti Kapoor Madan
Psychiatry
Your list of medicine has no anti OCD drug. Sleeping pills like nitrosun are not advised continuously for more than few weeks or the effect wanes. Mood stabilization is achieved by Dicorate ER . Based in your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. To take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions.
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User feedback


FAQs

What are the instructions for the storage and disposal of Stresnil 0.5 Tablet?

Keep Stresnil 0.5 Tablet in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

In which conditions is the use of Stresnil 0.5 Tablet contraindicated?

The use of Stresnil 0.5 Tablet is considered to be harmful for patients with known allergy to alprazolam or melatonin. Its use should also be avoided in patients with myasthenia gravis, any breathing difficulties or chest diseases, liver diseases and sleep apnea.

Can the use of Stresnil 0.5 Tablet cause dependence?

Stresnil 0.5 Tablet contains alprazolam which can make you dependent on the medicine. Dependence can lead to withdrawal symptoms when you stop the treatment abruptly. This mainly happens if you have been taking high doses or have been using it for a very long time. Withdrawal symptoms can include a headache, muscle pain, anxiety, restlessness, confusion, mood changes, difficulty in sleeping, irritability, nausea, vomiting, stomach upset and many others.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Melatonin. Barcarena, Portugal: Iberfar - Indústria Farmacêutica S.A.; 2018 [Accessed 26 Apr. 2019] (online) Available from:External Link
  2. MedIndia. Alprazolam+Melatonin. [Accessed 22 Apr. 2019] (online) Available from:External Link
Country of origin: India

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