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Tenebite-M 20/500 Tablet SR


Introduction of Tenebite-M Tablet SR

Tenebite-M 20/500 Tablet SR is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may also reduce your chances of having a heart attack or stroke.

Tenebite-M 20/500 Tablet SR can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels, and what other medicines you are taking. Taking it with meals helps to reduce the chances of developing an upset stomach.

You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking this medicine include diarrhea, nausea, vomiting, upset stomach, headache, and sore throat. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it.

This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver, or heart disease, problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines can affect this one so tell your doctor about all the medicines you are taking to make sure you are safe. You should try to avoid drinking alcohol as it lowers blood glucose. Your doctor will check your kidney function and blood sugar levels before and during treatment.

Side effects of Tenebite-M Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tenebite-M

  • Diarrhea
  • Nausea
  • Vomiting
  • Upset stomach
  • Headache
  • Nasal congestion (stuffy nose)
  • Sore throat
  • Respiratory tract infection
  • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea

How to use Tenebite-M Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tenebite-M 20/500 Tablet SR is to be taken with food.

How Tenebite-M Tablet SR works

Tenebite-M 20/500 Tablet SR is a combination of two antidiabetic medicines: Metformin and Teneligliptin. Metformin is an antidiabetic medication (biguanide). It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Tenebite-M 20/500 Tablet SR.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Tenebite-M 20/500 Tablet SR during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Tenebite-M 20/500 Tablet SR during breastfeeding is not available. Please consult your doctor.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Tenebite-M 20/500 Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Tenebite-M 20/500 Tablet SR may be needed. Please consult your doctor.
Use of Tenebite-M 20/500 Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Tenebite-M 20/500 Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Tenebite-M 20/500 Tablet SR may be needed. Please consult your doctor.
Tenebite-M 20/500 Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Tenebite-M 20/500 Tablet SR
₹6.44/Tablet SR
₹6.52/tablet sr
1% costlier
₹6.39/tablet sr
1% cheaper
Dynaglipt-M Tablet SR
Mankind Pharma Ltd
₹5.23/tablet sr
19% cheaper
₹5.25/tablet sr
18% cheaper
₹8.13/tablet sr
26% costlier

Quick tips

Tenebite-M Tablet SR

  • You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
  • Take it in addition to regular exercise and a healthy diet to lower levels of blood sugar.
  • Take it with food to lower your chance of having an upset stomach.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
  • Monitor your blood sugar level regularly while you are taking this medicine.
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Tenebite-M 20/500 Tablet SR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Fact Box

Habit Forming
No
Therapeutic Class
ANTI DIABETIC

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FAQs

Tenebite-M Tablet SR

Is it safe to use Tenebite-M 20/500 Tablet SR?

Yes, it is safe to use Tenebite-M 20/500 Tablet SR if you take it for the prescribed duration and according to the dosage advised by the doctor. However, despite taking the prescribed dosage you might experience common side effects like nausea, diarrhea, vomiting, stomach upset, headache, nasal congestion, sore throat, respiratory tract infection and hypoglycemia (low blood sugar level). Hypoglycemia is relatively common in patients who are taking Tenebite-M 20/500 Tablet SR in combination with insulin or Sulfonylurea. Inform your doctor if you experience any persistent problem while taking this medicine.

Can the use of Tenebite-M 20/500 Tablet SR lead to hypoglycemia?

The use of Tenebite-M 20/500 Tablet SR does not usually cause hypoglycemia (low blood sugar level) on its own. But, it could occur if there is insufficient supplementation of calories while taking this medicine. Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. The symptoms are more likely to be noticed if you miss or delay your food, drink alcohol, over-exercise or take any other antidiabetic medicine along with it. Hence, regular monitoring of blood sugar level is important. It is recommended to always carry glucose tablets, honey or fruit juice with you.

Can the use of Tenebite-M 20/500 Tablet SR cause nausea and vomiting?

Yes, the use of Tenebite-M 20/500 Tablet SR can cause nausea and vomiting. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without consulting a doctor.

Are there any specific contraindications associated with the use of Tenebite-M 20/500 Tablet SR?

The use of Tenebite-M 20/500 Tablet SR should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also considered to be harmful for patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.

Can the use of Tenebite-M 20/500 Tablet SR cause lactic acidosis?

Yes, the use of Tenebite-M 20/500 Tablet SR can lead to lactic acidosis which is also known as MALA (Metformin-associated lactic acidosis). It is caused by increased levels of lactic acid in the blood. It is a very rare side effect associated with the use of metformin and therefore it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Tenebite-M 20/500 Tablet SR and immediately consult your doctor.

Can the use of Tenebite-M 20/500 Tablet SR lead to Vitamin B12 deficiency?

Yes, the use of Tenebite-M 20/500 Tablet SR can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. Deficiency of B12 may cause anemia and nerve problems. These may further cause a tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). Consult your doctor if you experience these symptoms. Your doctor may advise monitoring of B12 levels and prescribe a vitamin B12 supplement if required.

What is the storage condition for the Tenebite-M 20/500 Tablet SR?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Kishimoto M. Teneligliptin: A DPP-4 inhibitor for the treatment of type 2 diabetes. Diabetes Metab Syndr Obes. 2013;6:187-95. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 08 Apr. 2019] (online) Available from:External Link
Country of origin: India

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