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Tetglob 1000IU Injection
Prescription Required
Product introduction
Tetglob 1000IU Injection is recommended for treatment of tetanus following injury in patients whose tetanus immunization is incomplete or uncertain. Tetanus causes convulsions (seizures) and severe muscle spasms that can be strong enough to cause bone fractures of the spine.
Tetglob 1000IU Injection provides immediate, short-term protection against the bacteria that causes tetanus (lockjaw). A single intramuscular (IM) injection is generally recommended for children and adults, with part of the dose infiltrated around the wound if it can be identified. This protection lasts long enough to protect your body until your body can produce its own antibodies against tetanus. It is to be administered only by or under the supervision of your doctor or other healthcare professional.
You may experience reactions such as slight soreness, pain and swelling at the site of injection injections and and slight temperature elevation. If you experience any othe symptoms on receiving the injection, let your doctor know. They may be able to help ways to manage the side effects.
Before receiving this injection, let your doctor know if you have any bleeding disorders. Avoid receiving the injection if you have a known history of allergy with this medicine. Pregnant and breastfeeding women should consult their doctors before receiving this injection.
Uses of Tetglob Injection
Benefits of Tetglob Injection
In Treatment of Tetanus
Tetanus causes a locked jaw, thus making it impossible to breathe, open the mouth to eat or swallow. Tetglob 1000IU Injection helps the body produce substances that resist infection from bacteria causing tetanus. Consult your doctor if you have any doubts.
Side effects of Tetglob Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tetglob
- Injection site reactions (pain, swelling, redness)
- Increased body temperature
How to use Tetglob Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Tetglob Injection works
Tetglob 1000IU Injection contains tetanus antibodies. It works by giving your body the antibodies it needs to protect it against tetanus infection.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tetglob 1000IU Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Tetglob 1000IU Injection during pregnancy is not available. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Tetglob 1000IU Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Tetglob 1000IU Injection does not usually affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Tetglob 1000IU Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Tetglob 1000IU Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Tetglob Injection?
If you miss a dose of Tetglob 1000IU Injection, consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Tetglob 1000IU Injection is given to prevent tetanus infection.
- It is to be given by a doctor or nurse in a hospital setting.
- Inform your doctor if you are suffering from any blood disorders before taking Tetglob 1000IU Injection.
- Tell your doctor if you are pregnant, think you may be pregnant, or are breastfeeding before this medicine is injected.
Fact Box
Chemical Class
Vaccines
Habit Forming
No
Therapeutic Class
VACCINES
Action Class
Immunoglobulin
Patient concerns
FAQs
How is tetanus caused?
Tetanus is caused by a toxin (poison) produced by the bacterium Clostridium tetani. The C. tetani bacteria cannot grow in the presence of oxygen. They produce spores that are very difficult to kill as they are resistant to heat and many chemical agents.
How does tetanus spread?
C. tetani spores can be found in soil, dust and manure of many household and farm animals and humans. The bacteria usually enter the human body in the presence of anaerobic (low oxygen) conditions through an open wound or puncture in the skin . These are the only favourable conditions for C. tetani to grow. It must be noted that tetanus does not spread from person to person.
How long does it take to show signs of tetanus after being exposed?
It may take around 3 to 21 days for the first symptoms to develop (incubation period). On an average, the symptoms usually appear on day 8. However, the time depends upon the site of infection which means if the injury site is far from the central nervous system, the longer will be the incubation period. The rate of risk with tetanus increases with a shorter incubation period.
What are the symptoms of tetanus?
An early symptom of tetanus includes spasm of the jaw muscles which is then followed by stiffness of the neck, difficulty in swallowing and stiffness of the abdominal muscles. Other signs include fever, sweating, elevated blood pressure and rapid heart rate. Spasms often occur, which may last for several minutes and continue for 3–4 weeks. Complete recovery, if it occurs, may take months altogether.
Is tetanus fatal?
Yes, tetanus can be fatal. In recent years, tetanus has been fatal in about 10% to 20% of reported cases.
Is tetanus curable?
No, there is no cure for tetanus once a person develops symptoms, just supportive treatment and management of complications. The best treatment of tetanus is its prevention through immunization.
How is Tetglob 1000IU Injection given?
Tetglob 1000IU Injection is administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. It is given either in the thigh muscle (for infants and young toddlers) or in the deltoid muscle (for older children and adults). Follow your doctor’s instructions carefully to get maximum benefit from Tetglob 1000IU Injection.
Who should not be given Tetglob 1000IU Injection?
Tetglob 1000IU Injection should not be given to someone who is suffering from any blood disorders which interfere with clotting or if a person is allergic to any of the ingredients of Tetglob 1000IU Injection. Consult your doctor if you are not sure.
How is Tetglob 1000IU Injection stored?
Tetglob 1000IU Injection is stored in the refrigerator (2-8°C). However, it may be stored at room temperature (25°C), in the dark for a short span of time (about a week), and this will not damage the medicine usually. But, it should be protected from direct sunlight and must not be freezed either.
The solution looks discolored. Can I still use Tetglob 1000IU Injection?
No. You should not use Tetglob 1000IU Injection if the medicine has changed colors or has particles in it. Normally, Tetglob 1000IU Injection is a clear to slightly cloudy, colorless to pale yellow sterile solution, available as single dose vials. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better that you discard the solution and go for another vial.
Who should not be given Tetglob 1000IU Injection?
Tetglob 1000IU Injection should not be given to someone who is suffering from any blood disorders which interfere with clotting or if a person is allergic to any of the ingredients of Tetglob 1000IU Injection. Consult your doctor if you are not sure.
How is Tetglob 1000IU Injection stored?
Tetglob 1000IU Injection is stored in the refrigerator (2-8°C). However, it may be stored at room temperature (25°C), in the dark for a short span of time (about a week), and this will not damage the medicine usually. But, it should be protected from direct sunlight and must not be freezed either.
The solution looks discolored. Can I still use Tetglob 1000IU Injection?
No. You should not use Tetglob 1000IU Injection if the medicine has changed colors or has particles in it. Normally, Tetglob 1000IU Injection is a clear to slightly cloudy, colorless to pale yellow sterile solution, available as single dose vials. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better that you discard the solution and go for another vial.
How is tetanus caused?
Tetanus is caused by a toxin (poison) produced by the bacterium Clostridium tetani. The C. tetani bacteria cannot grow in the presence of oxygen. They produce spores that are very difficult to kill as they are resistant to heat and many chemical agents.
How does tetanus spread?
C. tetani spores can be found in soil, dust and manure of many household and farm animals and humans. The bacteria usually enter the human body in the presence of anaerobic (low oxygen) conditions through an open wound or puncture in the skin . These are the only favourable conditions for C. tetani to grow. It must be noted that tetanus does not spread from person to person.
How long does it take to show signs of tetanus after being exposed?
It may take around 3 to 21 days for the first symptoms to develop (incubation period). On an average, the symptoms usually appear on day 8. However, the time depends upon the site of infection which means if the injury site is far from the central nervous system, the longer will be the incubation period. The rate of risk with tetanus increases with a shorter incubation period.
What are the symptoms of tetanus?
An early symptom of tetanus includes spasm of the jaw muscles which is then followed by stiffness of the neck, difficulty in swallowing and stiffness of the abdominal muscles. Other signs include fever, sweating, elevated blood pressure and rapid heart rate. Spasms often occur, which may last for several minutes and continue for 3–4 weeks. Complete recovery, if it occurs, may take months altogether.
Is tetanus fatal?
Yes, tetanus can be fatal. In recent years, tetanus has been fatal in about 10% to 20% of reported cases.
Is tetanus curable?
No, there is no cure for tetanus once a person develops symptoms, just supportive treatment and management of complications. The best treatment of tetanus is its prevention through immunization.
How is Tetglob 1000IU Injection given?
Tetglob 1000IU Injection is administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. It is given either in the thigh muscle (for infants and young toddlers) or in the deltoid muscle (for older children and adults). Follow your doctor’s instructions carefully to get maximum benefit from Tetglob 1000IU Injection.
Can Tetglob 1000IU Injection be given to pregnant women?
Yes, Tetglob 1000IU Injection can be taken by a pregnant woman. Cases of any fetal abnormalities in pregnant women have not been reported with the use of Tetglob 1000IU Injection. All pregnant women should receive Tetglob 1000IU Injection combined with other vaccines during pregnancy, preferably early between 27 and 36 weeks’ gestation. If a new mother hasn’t been vaccinated with Tetglob 1000IU Injection, she should receive it before hospital discharge. She can take Tetglob 1000IU Injection even if she is breastfeeding.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Human tetanus immunoglobulin [EMC SmPC]. Elstree, Hertfordshire: Bio Products Laboratory Limited; 1992 [revised Oct. 2014]. [Accessed 31 Jan. 2020] (online) Available from:
- RxList. Tetanus Toxoid. [Accessed 31 Jan. 2020] (online) Available from:
- Tetanus Immunoglobulin I.P. (Human) [Prescribing Information]. Ambernath, Maharashtra: Serum Institute of India. [Accessed 19 Oct. 2023] (online) Available from:
Marketer details
Name: Bharat Serums & Vaccines Ltd
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.
Country of origin: India
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