Tofajak XR Tablet is used to treat moderate to severe rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. It helps decrease pain, tenderness, and swelling in the joints by reducing inflammation. It also helps slow the progression of bone and joint damage.

Tofajak XR Tablet

Uses of Tofajak Tablet XR

Benefits of Tofajak Tablet XR

In Treatment of Rheumatoid arthritis

Tofajak XR Tablet works by blocking the action of some chemicals which cause inflammation. It can help reduce pain, stiffness, and swelling in your joints and slow down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking the medicine even if you feel well because it is preventing future harm as well as improving your symptoms.

In Treatment of Psoriatic arthritis

Psoriatic arthritis is a form of arthritis that affects some people who have psoriasis, a condition where the skin cells in the body grow too quickly and form scales and dry patches. Psoriatic arthritis is a type of inflammatory arthritis. Symptoms include joint pain, stiffness and swelling, which may flare and subside. Tofajak XR Tablet helps reduce pain, stiffness, and swelling associated with the condition. It also helps improve flexibility and prevents the disease progression. This way it helps in the management of psoriatic arthritis and enhances patients' quality of life.

In Treatment of Ankylosing spondylitis

Ankylosing spondylitis is a rare type of arthritis that affects the spine or larger joints. It usually starts in your lower back and can spread up to your neck or damage joints in other parts of your body. Tofajak XR Tablet helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

In Treatment of Ulcerative colitis

Ulcerative colitis is a disease of the large intestine (colon) and rectum in which the lining of the bowel becomes red and swollen. This can lead to bleeding, frequent diarrhea and abdominal pain. It relieves these symptoms and also helps you to stay well by preventing them from coming back. Drink plenty of fluids while on treatment with this medicine and stay hydrated.

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Side effects of Tofajak Tablet XR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tofajak

Upper respiratory tract infection
Headache
Diarrhea
Nasopharyngitis (inflammation of the throat and nasal passages)

How to use Tofajak Tablet XR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tofajak XR Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Tofajak Tablet XR works

Tofajak XR Tablet is a Janus kinase inhibitor. It works by blocking the action of the enzyme, Janus kinase. This decreases the activity of the immune system and inflammation associated with rheumatic diseases and ulcerative colitis.

Safety advice

Alcohol

SAFE

Consuming alcohol with Tofajak XR Tablet does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Tofajak XR Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Tofajak XR Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Tofajak XR Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Tofajak XR Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Tofajak XR Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Tofajak XR Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Tofajak XR Tablet may be needed. Please consult your doctor.

What if you forget to take Tofajak Tablet XR?

If you miss a dose of Tofajak XR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Tofajak XR Tablet

₹30.0/Tablet XR

Tofanta 11mg Tablet XR

Ajanta Pharma Ltd

₹73.5/tablet xr

162% costlier

Quick tips

Tofajak XR Tablet is used alone or in combination with other medicines for the treatment of rheumatoid arthritis, that did not improve with other anti-rheumatic drugs.
It may take take 3 to 6 months to feel the maximum effect of this medication. Keep taking it as prescribed.
Your doctor may get regular blood tests done to monitor your liver function, kidney function, blood counts, or cholesterol levels.
Tofajak XR Tablet can make it a bit harder for people to fight off infections. Inform your doctor if you have symptoms of an infection such as fever, chills, cough, and muscle aches.
Your doctor may get TB (tuberculosis) skin test and a chest X-ray before starting treatment with this medication.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Fact Box

Chemical Class

Pyrrolo Pyrimidine Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Janus kinase inhibitors

Patient concerns

I have joint pain in my rt wrist since 6 yrs. What are the possible reasons?

Dr. Trilok Kumar Jha

Orthopaedics

It may be Tenosynovitis, or Rheumatoid arthritis or any other type of arthritis

What is gatheya. What is it solution

Dr. Akshat Goel

Orthopaedics

It is supposed to be Rheumatoid Arthritis

FAQs

Can I take Tofajak XR Tablet if I have liver problems?

Inform your doctor if you have liver problems, before starting Tofajak XR Tablet. This is done because in some cases Tofajak XR Tablet may cause an increase in liver enzymes. Therefore, your liver function needs to be investigated before starting Tofajak XR Tablet. Although, Tofajak XR Tablet can be given to patients with mild to moderate liver function impairment, but should not be prescribed to patients with severe liver impairment.

Can Tofajak XR Tablet cause cancer?

Tofajak XR Tablet may increase the chances of developing the risk of certain cancers (lymphoma and other cancers including skin cancers) by affecting the working of the immune system. Hence, inform your doctor if you ever had or have any type of cancer.

What is Tofajak XR Tablet used for?

Tofajak XR Tablet is approved for use in people with moderate to severe rheumatoid arthritis. It is an inflammatory disease of the joints. It is used if previous therapy did not work well or did not suit the patient. However, it can also be used earlier in treatment if the person does not respond well to the prescribed drugs. It can be used alone or together with some other medicines, such as methotrexate.

How long does it take for Tofajak XR Tablet to start working?

Tofajak XR Tablet usually takes about 2 to 8 weeks before you start feeling better, and it can take 3 to 6 months to feel the maximum effect of this medication.

Do I need to get any investigations done before starting Tofajak XR Tablet?

You may need to get your blood tests done before you start Tofajak XR Tablet or while you are taking it. Blood tests are done in order to check if you have a low red blood cell count (anemia), low white blood cell count (neutropenia or lymphopenia), high blood fat (cholesterol) or high levels of liver enzymes. It also helps to ensure that treatment with Tofajak XR Tablet is not causing problems. In addition to this, your doctor may advise you to get tested for tuberculosis before starting Tofajak XR Tablet, as using Tofajak XR Tablet may make an existing infection worse.

Can Tofajak XR Tablet cause infections?

Tofajak XR Tablet is a medicine that affects your immune system. This may reduce your ability to fight infection and may increase the risk of getting a serious infection including tuberculosis. It may also include infections caused by severe fungal, bacterial or viral infections that spread through the body. In some cases, these infections can be life-threatening and may even cause death. Hence, it is advised to treat these infections in a hospital.

If I am already taking tocilizumab, can I take Tofajak XR Tablet?

No, you should not take tocilizumab along with Tofajak XR Tablet. Tofajak XR Tablet affects the immune system, so you should avoid taking it with any other immunity-affecting medicine. Taking both medicines together can further increase the risk of infection and may lead to further complications.

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Related lab tests

Anti Neutrophilic Cytoplasmic Antibody - P

C- Reactive Protein Quantitative

Erythrocyte Sedimentation Rate

HLA - B27, PCR

Rheumatoid Factor - Agglutination

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Rheumatoid Factor IgG Antibody

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1373-74.
Tofacitinib. New York, New York: Pfizer Labs; 2012 [revised Nov. 2012]. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Tofacitinib. [Accessed 02 Apr. 2019] (online) Available from:
Tofacitinib [Prescribing Information]. New York, NY: Pfizer labs; 2022. [Accessed 07 Aug. 2023]. (online) Available from:

Marketer details

Name: Cipla Ltd

Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Tofajak XR Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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