Topenzo Tablet is a pain relieving medicine. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It may also be used to relieve fever, muscle pain, back pain, toothache, or pain in the ear and throat.

Topenzo Tablet should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for a longer duration than recommended by your doctor.

Some of the common side effects of this medicine include nausea, vomiting, heartburn, diarrhea, loss of appetite, and indigestion. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help you with ways to reduce or prevent the side effects.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, liver, or have stomach ulcers. To make sure it is safe for you, let your doctor know about all the other medicines you are taking. Pregnant and breastfeeding mothers should first consult their doctors before using this medicine.

Uses of Topenzo Tablet

Pain relief

Benefits of Topenzo Tablet

In Pain relief

Topenzo Tablet relieves pain, reduce swelling and ease inflammation in conditions like rheumatoid arthritis, osteoarthritis and ankylosing spondolytis. It also gives relief from muscle and back pain, toothache, or pain in the ear and throat. It works by reducing substances in the body that causes pain and swelling. Take it as prescribed to get the most benefit. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Topenzo Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Topenzo

Nausea
Vomiting
Heartburn
Indigestion
Diarrhea
Loss of appetite
Stomach pain

How to use Topenzo Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Topenzo Tablet is to be taken with food.

How Topenzo Tablet works

Topenzo Tablet is a combination of four medicines: Trypsin, Bromelain, Rutoside and Diclofenac. Trypsin and Bromelain are enzymes. They increase blood supply and make the body produce substances that fight pain and swelling. Rutoside is an antioxidant which protects the body from damage by chemicals (free radicals) and further reduces swelling. Diclofenac is a non-steroidal antiinflammatory drug (NSAID) which works by blocking the release of certain chemical messengers (prostaglandins) in the brain that cause pain and inflammation (redness and swelling).

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Topenzo Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Topenzo Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Topenzo Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Topenzo Tablet may cause side effects which could affect your ability to drive.
Topenzo Tablet may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Topenzo Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Topenzo Tablet may not be needed in these patients. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Topenzo Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Topenzo Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Topenzo Tablet?

If you miss a dose of Topenzo Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Topenzo Tablet

₹11.3/Tablet

Enzomac Plus Tablet

Macleods Pharmaceuticals Pvt Ltd

₹12.8/tablet

13% costlier

Rutoheal-D Tablet

Mankind Pharma Ltd

₹11.5/tablet

2% costlier

Xymoheal D Tablet

Corona Remedies Pvt Ltd

₹12.4/tablet

10% costlier

Flamar 3D Tablet

Indoco Remedies Ltd

₹10.8/tablet

4% cheaper

Thrize Plus Tablet

Pharmed Ltd

₹11.5/tablet

2% costlier

View all substitutes

Quick tips

Topenzo Tablet helps relieve pain and inflammation that may occur due to trauma, surgery or everyday activity.
It may also be used to relieve inflammation in rheumatic and degenerative conditions, such as rheumatoid arthritis and osteoarthritis.
Take it with plenty of fluids, an hour before or two hours after a meal.
It may increase the severity of your condition at the start of treatment. Continue using it as prescribed by your doctor.
It may cause dizziness and blurred vision. Do not drive or do anything requiring concentration until you know how it affects you.
It may change the color, consistency, and odor of your stool. This is harmless. Inform your doctor if this bothers you.

Fact Box

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Patient concerns

One of my teeth is sensitive. It some times pains

Dr. Abhijit Gambhir

Dental Surgery

sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

No take Crocin for pain relief

FAQs

What is Topenzo Tablet?

Topenzo Tablet is a combination of four medicines: Trypsin, Bromelain, Rutoside and Diclofenac. This medication helps in relieving pain and swelling (inflammation). It works by lowering the levels of those chemical substances in the body which cause pain and swelling (inflammation).

Can the use of Topenzo Tablet cause dizziness?

Yes, the use of Topenzo Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.

Are there any specific contraindications associated with the use of Topenzo Tablet?

The use of Topenzo Tablet is considered to be harmful for patients with known allergy to painkillers (NSAIDs) or any of the components or excipients of this medicine. The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer / bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.

Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Topenzo Tablet can increase the risk of side effects like nausea, vomiting, heartburn, indigestion, diarrhea and can also damage your kidneys on long-term use. If you are experiencing increased severity of pain and swelling which is not relieved by the recommended doses of this medicine, please consult your doctor for re-evaluation.

What is the recommended storage condition for Topenzo Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can Topenzo Tablet be stopped when my pain and swelling (inflammation) are relieved?

Topenzo Tablet is usually used for short term and can be discontinued when pain and swelling are relieved. However, Topenzo Tablet should be continued if the doctor has advised you to do so.

Can the use of Topenzo Tablet cause nausea and vomiting?

Yes, the use of Topenzo Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to a doctor.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Shah D, Mital K. The Role of Trypsin:Chymotrypsin in Tissue Repair. Adv Ther. 2018;35(1):31-42. [Accessed 22 Apr. 2019] (online) Available from:
ScienceDirect. Bromelain. [Accessed 02 Apr. 2019] (online) Available from:
Drugs.com. Rutin. [Accessed 22 Apr. 2019] (online) Available from:
Diclofenac. Daventry, Northamptonshire: Dexcel Pharma Ltd.; 1996 [revised 20 Dec. 2017]. [Accessed 22 Apr. 2019] (online) Available from:

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.