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Last updated
05 Dec 2023 | 06:14 PM (IST)

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Topotel 4mg Injection


Product introduction

Topotel 4mg Injection is used in the treatment of ovarian cancer. It shows its working by stopping or slowing down the growth of cancer cells.

Topotel 4mg Injection is used to treat various types of cancer

Uses of Topotel Injection

Benefits of Topotel Injection

In Ovarian cancer

Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Topotel 4mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. Consult your doctor to know about ways that can help you avoid these side effects.

Side effects of Topotel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Topotel

  • Tiredness
  • Vomiting
  • Weakness
  • Nausea
  • Abdominal pain
  • Indigestion
  • Decreased white blood cell count
  • Decreased blood cells (red cells, white cells, and platelets)
  • Diarrhea
  • Injection site reactions (pain, swelling, redness)

How to use Topotel Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol
SAFE
Consuming alcohol with Topotel 4mg Injection does not cause any harmful side effects.
Pregnancy
CONSULT YOUR DOCTOR
Topotel 4mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Topotel 4mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Topotel 4mg Injection may cause side effects which could affect your ability to drive.
Topotel 4mg Injection can make you feel tired and this may affect your ability to drive.
Kidney
CAUTION
Topotel 4mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Topotel 4mg Injection may be needed. Please consult your doctor.
Use of Topotel 4mg Injection is not recommended in patients with end-stage kidney disease.
Liver
SAFE IF PRESCRIBED
Topotel 4mg Injection is safe to use in patients with liver disease. No dose adjustment of Topotel 4mg Injection is recommended.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Topotel 4mg Injection
₹7172.0/Injection
Topocan 4mg Injection
Venus Remedies Ltd
₹2137.5/injection
70% cheaper

Quick tips

  • Topotel 4mg Injection helps treat ovarian cancer.
  • It is given by a drip into a vein (intravenous infusion).
  • Do not drive or operate machinery as Topotel 4mg Injection may cause tiredness, drowsiness or weakness.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Your doctor may get regular blood tests done to monitor your blood cells during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Fact Box

Chemical Class
Camptothecin Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Topoisomerase Inhibitor

Patient concerns

arrow
ovarian cancer stage 3 c surgery done chemotheraphy done
Dr. Aanchal Maheshwari
Ayurveda
C?se has to be seen in person before starting the treatment
My mother dignosis with stage4 ovarian cancer, 1st done on 24th of may 16, I need a alternative medicine parallelly
Dr. Manju Singh
Homeopathy
I would like to recommend you that please continue your treatment as advice by your doctor.
arrow

FAQs

How often is Topotel 4mg Injection given?

Generally Topotel 4mg Injection treatment is for 4 cycles of 21 day each, patient is given Topotel 4mg Injection for first 5 days of each cycle.

Does Topotel 4mg Injection cause hair loss?

Yes, Topotel 4mg Injection may cause temporary hair loss.

Does Topotel 4mg Injection cause flare reaction?

Yes, Topotel 4mg Injection may cause flare reaction.

How long does Topotel 4mg Injection take to work?

Topotel 4mg Injection may start its action once the infusion is started, however, the complete effect may be assessed only after completion of 4 cycles.

Is Topotel 4mg Injection a vesicant?

Topotel 4mg Injection is a vesicant (irritant).

Is Topotel 4mg Injection effective?

Yes Topotel 4mg Injection is effective if used at prescribed doses for the prescribed duration as advised by your doctor.

What is Topotel 4mg Injection chemotherapy?

It is a treatment therapy that includes Topotel 4mg Injection with or without combination of other drugs in treatment of cancer (Usually ovarian or lung cancer).

How is Topotel 4mg Injection administered?

Topotel 4mg Injection is either administered orally as a capsule or as an intravenous Infusion in the arm over a period of 30 min.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1711-12.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 951.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1383.
  4. Topotecan hydrochloride. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 1996 [revised 23 Apr. 2018]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  5. Topotecan. Unterach, Austria: Ebewe Pharma; 1996 [revised Feb. 2014]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
  7. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Topotecan. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:External Link

Marketer details

Name: Fresenius Kabi India Pvt Ltd
Address: Fresenius Kabi AG​ , Else-Kröner-Straße 1 ​ , 61352 Bad Homburg , Germany
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Topotel 4mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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4.0 ml in 1 vial
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